A method for predicting risk exposure can include receiving a set of data collected via a smart ring. The method also can include analyzing, via a trained machine learning (ML) model, the set of data collected via the smart ring to determine whether the set of data collected via the smart ring (a) represents an impairment pattern or (b) correlates to a high-risk pattern, wherein at least one of the impairment pattern or the high-risk pattern correlates to a risk exposure. The method for predicting risk exposure further can include generating a notification to alert a user of the risk exposure. Other embodiments are disclosed.

A flexible, multi-layered device for automatically sensing sweat biomarkers, storing and transmitting sensed data via wireless network to a computing device having software applications operable thereon for receiving and analyzing the sensed data. The device is functional in extreme conditions, including extremely hot temperatures, extremely cold temperatures, high salinity, high altitude, extreme pHs, and/or extreme pressures.

Physiological sign monitoring devices, and systems and computer-implemented methods of remote physiological monitoring of subjects. A monitoring device includes a plurality of physiological sign monitoring portions. Each physiological sign monitoring portion of the device is configured for deployment on a different, respective surface of a subject including a surface on the back of an ear of the subject, a surface over a mastoid region of the neck of the subject, and a surface over another region of the neck of the subject. Each physiological sign monitoring portion of the device includes a plurality of physiological sensors, where each sensor is configured to generate a respective electronic signal based on a respective monitored physiological parameter of the subject. At least one physiological sensor in each physiological sign monitoring portion of the device is configured to generate a respective electronic signal based on the same monitored physiological parameter of the subject.

Disclosed are reactive dyes and preparation methods thereof. The reactive dye may be prepared using heterocyclic primary amine as a diazo component, 4,4-diamino-2,2-stilbenedisulfonic acid, s-triazine, or ethylenediamine as a bridging group, and a dimonochlortriazine group as an active group. The color-changing compound is covalently bonded into the fiber chemical structure by nucleophilic substitution reaction between monochlorotriazine and the hydroxyl group in a textile structure, and the size of the conjugated system and the range of electron delocalization of the dye are changed by a reversible isomerization reaction of the hydroxyl group adjacent to the diazo group and the diazo group under different pH regulations. Moreover, the dye has a double color changing structure, which improves the capability of the dye combined with H/OH. The pH value range that can cause color changes in the dye is effectively expanded to include weak alkali, weak acid or even neutral conditions.

According to an aspect, there is provided an apparatus (100) comprising a sweat sensing component (102) for measuring a parameter relating to sweat generated by sweat glands of a subject; a sweat transport channel (104); and a sweat redirecting component (106) comprising a responsive material whose form is configured to change in response to a stimulus, so as to redirect sweat and control an amount of sweat able to be transported to the sweat sensing component (102) via the sweat transport channel (104), wherein the sweat redirecting component is positioned at an outlet of the sweat transport channel, such that, in a first configuration, the form of the responsive material is such that the sweat redirecting component prevents the passage of sweat through the outlet, and directs the passage of sweat to the sweat sensing component; and, in a second configuration, the form of the responsive material is such that the sweat redirecting component permits the passage of sweat through the outlet.

Described here are patches and methods for measuring glucose in sweat (and tears and the like). In general, the patches comprise an adhesive layer adapted to bond to skin of an individual, a substrate layer disposed over the adhesive layer and comprising a glucose sensing complex including a chromogen that changes color in the presence of certain concentrations of glucose, and a cover. In typical embodiments, the substrate layer has elements formed to direct and accumulate sweat that migrates from the skin of the individual to the glucose sensing complex. Methods of using the invention can comprise cleaning the skin surface, collecting sweat in a patch comprising this microfluidic constellation of elements, and observing concentrations of glucose collected in the sweat, for example either visually, or by using a smartphone or other computer processing device.

A wearable heat stress monitor (100) comprising: a first sensor (110). the first sensor (110) comprising an electrode (115) for sensing a sweat parameter (110A) and at least one further sensor (120) for sensing a body parameter or an environmental parameter (120A). The heat stress monitor (100) further comprises a processor (130) to determine a heat stress level based on the sweat parameter (110A) sensed by the first sensor (110) and the body parameter or environmental parameter (120A) sensed by the at least one further sensor (120) and an output module (140) for outputting information based on the heat stress level determined by the processor (130).

A multi-composite electrochemical cell substantially consists of a thin polymer membrane including three different adjacent sectors, which are made of the same appropriately seamlessly modified polymer, incorporating in the polymer one or more conductive phases, or conductive fillers, such as graphene, metal, or a combination thereof. In the first sector the polymer material incorporates graphene nanoplatelets and acts as a cathode; in the second sector, interposed between the other two, the polymer material acts as an insulating spacer; in the third sector the polymer material incorporates graphene nanoplatelets and a metal filler or immersed metal contact rheophore, with negative standard reduction potential, and acts as an anode; wherein the metal filler is in the form of dispersed powder or dispersed flakes, or of a thin sheet incorporated in the polymer.

The disclosure provides: a two-way communication means between a sweat sensing device and a user; at least one means of activating, deactivating, controlling the sampling rate, and controlling the electrical power applied to a particular sweat sensor or group of sensors; a means of isolating a sweat sensor from sweat until needed; a means of selectively stimulating sweat for a particular sweat sensor or group of sensors to manage sweat flow or generation rate; a means of monitoring the power consumption of a sensor device, individual sensors or groups of sensors; a means of monitoring an individual sweat sensor or group of sensors for optimal performance; a means of monitoring whether a sweat sensing patch is in adequate proximity to a wearer's skin to allow device operation; and the ability to use aggregated sweat sensor data correlated with external information to enhance the device's management capabilities.

A wearable sensing platform includes sensors and circuits to sense aspects of a user's state by analyzing bodily fluids, such as sweat and/or urine, and a user's temperature. A sensor array senses a plurality of different body fluid analytes, optionally at the same time. A signal conditioner is coupled to the sensor array. The signal conditioner conditions sensor signals. An interface is configured to transmit information corresponding to the conditioned sensor signals to a remote computing device. The wearable sensing platform may include a flexible printed circuit board to enable the wearable sensing platform, or a portion thereof, to conform to a portion of the user's body.