The invention relates to a drug abuse prevention device and a method thereof, said device comprising a sweat analysis system configured to determine content of drugs from sweat of a user; an air quality determination unit configured to determine the presence of drug contents in the air, a processor configured to compare the determined content of drugs in air and sweat of user with pre determined drug levels; and an auto trigger unit configured to trigger one or more registered users regarding the presence of drugs upon violation of predetermined drug levels.

Provided is a system for correcting a sweat analyte measurement for temperature. The system comprises a sweat collector (106) for collecting sweat from skin (102). The collected sweat is drawn from the sweat collector to an outlet (110) via a capillary (108). The sweat is drawn through the capillary by capillary action and evaporation of the sweat from the outlet. The evaporation of the sweat from the outlet depends on the temperature. A flow sensor (112) measures a flow rate of the sweat being drawn through the capillary. An analyte sensor (114) obtains the sweat analyte measurement. The system further comprises a controller which is configured to determine a temperature from the measured flow rate. The sweat analyte measurement is then corrected using the determined temperature. Further provided is a method for correcting a temperature-dependent sweat analyte measurement

Disclosed are novel compositions, devices, patches, systems and methods that are useful for estimating, determining, modulating and/or improving the sleep/wake and/or circadian phase of a subject (e.g., a human subject) by the dispensing of measured quantities of agents to a subject or into an environment of the subject and the continuous monitoring and/or tracking of the subject's consciousness (e.g., sleep/wake) patterns. In certain aspects, the compositions, devices, patches, systems and methods disclosed herein are capable of delivering one or more agents to a subject in response to measured consciousness patterns estimations and circadian phase estimations, thereby aligning the subject's circadian biology to the external environment and improving the quality and duration of sleep.

Provided is a method (400) of positioning a sweat sensor device (100), the method comprising: determining (410) a first skin location (i) of a mammalian subject, which first skin location (i) contains apocrine and eccrine sweat glands; determining (420) a second skin location (ii), adjacent to the first skin location (i), and having a different sweat gland composition than the first skin location, wherein at the second skin location (ii), predominantly eccrine sweat glands are present, and wherein the determining (410, 420) of the first (i) and second (it) skin locations is achieved by detecting differences between the first (i) and second (ii) skin locations; and positioning (430) the sweat sensor device (100) such that a first part of the sweat sensor device (100) is present on the first skin location (i), while a second part of the sweat sensor device (100) is present on the second skin location (ii).

The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

An allergy test kit including a housing, a biosensor supported by the housing, the biosensor operable to detect a presence of immunoglobin A (IgA) in a sample of sweat of a user and to generate IgA presence data, an allergen sensor supported by the housing, the allergen sensor operable to detect a presence of an allergen in a substance sample provided by the user and to generate allergen presence data, a processor operable to receive the IgA presence data from the biosensor and the allergen presence data from the allergen sensor, and a memory operable to store the IgA presence data and the allergen presence data.

Techniques and systems are disclosed for implementing textile-based screen-printed amperometric or potentiometric sensors. The chemical sensor can include carbon based electrodes to detect at least one of NADH, hydrogen peroxide, potassium ferrocyanide, TNT or DNT, in liquid or vapor phase. In one application, underwater presence of chemicals such as heavy metals and explosives is detected using the textile-based sensors.

The present invention relates to body fluid monitoring. It is proposed to incorporate a reagent-free calibration method into a patch or wearable. The method comprises capturing molecules of interest, i.e. calibration molecules inside the bioliquid of the patient, and release them when needed for calibration. This eliminates the need for onboard reagent storage. Because the calibration is done in the same bioliquid, any matrix effects are corrected for.

A device for increasing a concentration of at least one analyte in an advective flow of biofluid includes an agent for enhancing a paracellular permeability of an epithelial tissue; and an iontophoresis electrode and a counter electrode, which are adapted to increase the concentration of said analyte in the advective flow of the biofluid. A method of sensing an analyte in a biofluid includes increasing a paracellular permeability of an epithelial tissue layer; and inducing electro-osmotic flow by reverse iontophoresis to increase a concentration of said analyte in an advective flow of the biofluid, wherein said advective flow is driven by at least one of saliva generation, sweat generation, or reverse iontophoresis.

A wearable monitoring system includes a first flexible substrate encapsulating a current ramping system to provide a current to an electrode in direct contact with a predetermined location of skin of a user to promote bodily fluid secretion, and a second flexible substrate placed over the predetermined location, the second flexible substrate having an integrated electrochemical sensor to determine bodily fluid concentration levels secreted through the skin.