A system to determine medication adherence may include a chemical marker sensor, a verification sensor, and a processor. The chemical marker sensor may be configured to detect one or more markers in sweat vapor of a user. The verification sensor may be configured to detect whether the system is in use. The processor may be communicatively coupled to the chemical marker sensor and the verification sensor and may be configured to determine whether the user has taken a therapeutic agent that includes the one or more markers based on signals generated by the chemical marker sensor and the verification sensor.

Systems and methods are disclosed that provide smart alerts to users, e.g., alerts to users about diabetic states that are only provided when it makes sense to do so, e.g., when the system can predict or estimate that the user is not already cognitively aware of their current condition, e.g., particularly where the current condition is a diabetic state warranting attention. In this way, the alert or alarm is personalized and made particularly effective for that user. Such systems and methods still alert the user when action is necessary, e.g., a bolus or temporary basal rate change, or provide a response to a missed bolus or a need for correction, but do not alert when action is unnecessary, e.g., if the user is already estimated or predicted to be cognitively aware of the diabetic state warranting attention, or if corrective action was already taken.

The present disclosure provides systems and methods for the determining a rate of change of one or more analyte concentrations in a target using non invasive non contact imaging techniques such as OCT. Generally, OCT data is acquired and optical information is extracted from OCT scans to quantitatively determine both a flow rate of fluid in the target and a concentration of one or more analytes. Both calculations can provide a means to determine a change in rate of an analyte over time. Example methods and systems of the disclosure may be used in assessing metabolism of a tissue, where oxygen is the analyte detected, or other functional states, and be generally used for the diagnosis, monitoring and treatment of disease.

A portable communication device (100) automatically determines user hydration levels while the device is being transmitted. The portable communication device comprises a humidity sensor (120) located by a microphone and touch sensors (124) located on a push-to-talk (PTT) button (110). Data is gathered during PTT switch activation (112). No additional steps are required by the user. Alerts (140) are provided when predetermined dehydration thresholds are approached.

A device and method for determining an excretion flow rate of a body fluid of a person or an animal. The device includes an absorbent element equipped with at least three electrodes connected to a measuring system for measuring at least one electric parameter so as to be electrically coupled two by two and to form at least two pairs of electrodes, separating systems which include an inlet opening exposing a part of the absorbent element so as to create a diffusion path. At least two of the electrodes are first electrodes placed along the diffusion path in such a way that each of the first electrodes is at a distance from the inlet opening representative of a volume of absorbed fluid.

The present disclosure relates to the field of electronic engineering. The present disclosure envisages a multifunction modular strap that integrates multiple health monitoring devices. The multifunction modular strap comprises a health sensing module, an activity tracking module, a signal conditioning unit, a processing unit, a notification module, and a communication module. The health sensing module has a plurality of health sensors configured to sense a plurality of health parameters associated with a user. The activity tracking module comprises a pedometer, a sleep detection module, and a gesture detection module. The signal conditioning unit co-operates with the health sensing module and the activity tracking module. The processing unit co-operates with the signal conditioning unit, the health sensing module and the activity tracking module. The notification module co-operates with the processing unit and notifies the user. The communication module receives at least one communication signal from the processor and enables bi-directional communication with communicatively coupled device.

The invention disclosed generally relates to sensors, systems and methods for the detection of an analyte in a complex sample.

A wearable sensor decal may include a flexible wrapper layer, an intermediate layer, and a porous film layer. A first plurality of electrodes may be deposited on the wrapper layer. A heating element may be conductivity coupled to the first plurality of electrodes. A second plurality of electrodes may be deposited on the intermediate layer. A biosensor may be conductively coupled to the second plurality of electrodes. The flexible film may be hydrophilic to allow biofluids pass to the biosensor and the wrapper layer may be hydrophobic to provide waterproofing to the biosensor and heating element. The heating element may be powered to reduce thermal variance in biosensor measurements.

Devices and methods are provided for continuous measurement of an analyte concentration. The device can include a sensor having a plurality of sensor elements, each having at least one characteristic that is different from other sensor(s) of the device. In some embodiments, the plurality of sensor elements are each tuned to measure a different range of analyte concentration, thereby providing the device with the capability of achieving a substantially consistent level of measurement accuracy across a physiologically relevant range. In other embodiments, the device includes a plurality of sensor elements each tuned to measure during different time periods after insertion or implantation, thereby providing the sensor with the capability to continuously and accurately measure analyte concentrations across a wide range of time periods. For example, a sensor system 180 is provided having a first working electrode 150 comprising a first sensor element 102 and a second working electrode 160 comprising a second sensor element 104, and a reference electrode 108 for providing a reference value for measuring the working electrode potential of the sensor elements 102, 104.

A dehydration estimation device includes one or more processors and a storage device storing a program to be executed by the one or more processors, the program including instructions for estimating a blood electrolyte concentration of a measurement subject, and determining presence or absence of dehydration of the measurement subject on a basis of the blood electrolyte concentration.