An electronic sweat sensor (300) includes a plurality of porous substrates (310, 312), each porous substrate (310, 312) having an electrically conductive surface (320, 322). The porous substrates (310, 312) have a generally planar surface. The generally planar surface may be adapted to be positioned on skin (12) generally coplanar with the skin. The electronic sweat sensor (300) further includes a porous spacer (315) layer defining a gap between at least two of the porous substrates (310, 312). When an analyte flow (305), which may be from skin (12), is moving perpendicular to the planar surface and through at least one of the porous substrates (310, 312), at least one of the conductive surfaces (320, 322) provides an electrical response to the presence of the analyte flow (305).

The concentration of an administered compound, such as a drug (D), in an organ or a bodily fluid, such as blood, is determined directly through detecting the drug (D) or its metabolites (DM) in sweat. The concentration may be determined indirectly by administering the drug (D) together with one or more tracer compounds (T, T2) or metabolites thereof (TM, T2M) or by detecting concentrations and trends of other analytes present in the body that react to the presence of the drug (D). By determining tracer concentration in sweat, the concentration of the drug (D) in blood or an organ can be determined. The tracer (T, T2) is a compound selected for ease of detection in sweat, known metabolic and solubility profiles that correspond to those of the drug (D), and safety of use. A smart transdermal delivery patch (300) is used to administer a dosage of drug to a wearer in coordination with at least one sweat sensor (324) reading conveying information about the wearer.

The present invention is directed to a wearable system wherein elements of the system, including various sensors adapted to detect biometric and other data and/or to deliver drugs, are positioned proximal to, on the ear or in the ear canal of a person. In embodiments of the invention, elements of the system are positioned on the ear or in the ear canal for extended periods of time. For example, an element of the system may be positioned on the tympanic membrane of a user and left there overnight, for multiple days, months, or years. Because of the position and longevity of the system elements in the ear canal, the present invention has many advantages over prior wearable biometric and drug delivery devices.

The present invention is directed to a wearable system wherein elements of the system, including various sensors adapted to detect biometric and other data and/or to deliver drugs, are positioned proximal to, on or in the ear canal of a person. In embodiments of the invention, elements of the system, including drug delivery devices, are positioned on or in the ear canal for extended periods of time. For example, an element of the system may be positioned on the tympanic membrane of a user and left there overnight, for multiple days, months, or years. Because of the position and longevity of the system elements in the ear canal, the present invention has many advantages over prior wearable biometric and drug delivery devices.

A set of biometric data about the athlete and a set of environmental data about a sporting event in which the athlete is to compete are received at a first time. Using previously saved data, a relationship is determined between a biometric factor of another athlete, an environmental factor of a previous sporting event, and an outcome of the previous sporting event. Using a subset of the set of biometric data and a subset of the set of environmental data, in conjunction with the relationship, a probability of a desired outcome of the athlete's performance in the sporting event is determined. A composition of the sports nutrition, a dosage of the composition, and a time of administering the dosage are computed and recommended for administering to the athlete to change the probability of the desired outcome to a second probability.

A biosensor is for sensing analytes in a fluid. The biosensor may include a first structural layer having a first hydrogel, a second structural layer having a second hydrogel, and a bioactive region extending between the first structural layer and the second structural layer and having a third hydrogel. The biosensor may include a first electrode coupled to the bioactive region, and a second electrode coupled to the first structural layer and being spaced apart from the bioactive region. The second structural layer may have a through opening adjacent the bioactive region, and the bioactive region may be configured to be in fluid communication with an environment external to the biosensor for receiving the fluid comprising the analytes.

The present invention includes a flexible sensor suitable for contact with skin comprising: a nanocomposite; and a top layer; where the sensor provides in-situ detection in sweat or other aqueous body fluids at the skin surface of at least one physiological parameter selected from the group consisting of a physiological salt component, temperature, moisture, humidity, or combinations thereof. The present invention further includes a method of fabricating a flexible sensor suitable for contact with skin comprising: electrospinning at least one polyamide-producing monomer to form a non-conductive polyamide substrate; attaching at least one plurality of conductive nanoscale attachments, wherein the nanoscale attachments are selected from nanotubes, nanoparticles, or combinations thereof, to form an intermediate layer; and functionalizing the intermediate layer to form a top layer.

A wearable consumer electronic product includes at least a housing arranged to catty operational components comprising a processor and a band having a pliable band body and a securing means arranged to secure the band body to the housing. In one embodiment, the pliable band body has a size and shape suitable for wrapping around an individual appendage and that includes an opening that leads to a cavity within the band body suitable for accumulating an amount of water and a band sensor embedded within the band body in communication with the cavity.

A three-dimensional conductive patch is provided herein, the three-dimensional conductive patch comprising: a layer having a plurality of interlaced fibres including conductive fibres and non-conductive fibres, the layer having: a base fabric surface as a first portion extending from a first side of the layer to a second side of the layer and extending from a first end of the layer to a second end of the layer, and a group of conductive fibres as a second portion, a first base fibre of the layer positioned at a first end of the second portion and a second base fibre of the layer positioned at a second end of the second portion such that the second portion is positioned relative to the first portion via first base fibre and the second base fibre, the second portion interlaced with the first base fibre at the first end of the second portion and interlaced with the second base fibre at the second end of the second portion; wherein the second portion forms a loop extending from the base fabric surface, the loop having an apex spaced apart from the first portion, a first part of the loop extending from the first base fibre towards the apex and a second part of the loop opposed to the first part and extending from the second base fibre towards the apex; the second portion integral with the first portion.

Technologies and implementations for wearable healthcare devices are generally disclosed.