A transcutaneous electrical stimulation system is provided that can include a number of features. In one implementation, the system can include a plurality of electrodes configured to be in contact with a skin surface of a patient. The system can further include a flexible hub electrically connected to the electrodes and configured to be in contact with the patient. A bend sensor can be disposed in the hub and configured to measure a curvature of the hub. The system can include a signal processing device electrically coupled to the plurality of electrodes and the bend sensor, the signal processing device being configured to change stimulation settings of the plurality of electrodes based on the curvature of the hub. In some implementations, the system can include a multi-channel stimulator. Methods of use are also provided.

A method for dispensing a personalized beverage mixture includes receiving a predicted volume of fluid lost by a user through sweat based on activity data indicating a type of activity performed and one or more parameters for the activity, receiving a measurement of an amount of electrolytes lost by the user through sweat, generating a recipe for the personalized beverage mixture based on the predicted volume of fluid and the measured amount of electrolytes lost by the user, the recipe including a second volume of fluid to replenish at least a portion of the predicted volume of fluid lost by the user and an amount of electrolyte additive to replenish at least a portion of the measured amount of electrolytes lost by the user, and dispensing the personalized beverage mixture according to the recipe.

A sweat extraction and monitoring system comprises a triboelectric nanogenerator (TENG) for inducing localized sweating for a human skin to generate sweat, iontophoresis electrodes electrically connected to the TENG and configured to be operably electrically contacting the human skin, at least one microfluidic channel for receiving the sweat, at least one biosensor for sensing the sweat received in the at least one microfluidic channel, and at least one sweat-activated battery configured to be actuatable by the sweat for powering the at least one biosensor.

Systems and methods of analyzing biological fluid biomarkers, calculating biomarker data, transmitting data to a transceiver device, and storing the data and/or analytics in a database and/or on at least one remote computer server.

Among others, the present invention provides devices each including a micro-filter, a shutter, a cell counter, a selector, a micro-surgical kit, a timer, and a data processing circuitry, wherein the micro-filter is capable of detecting or filtering circulating tumor cells.

A wireless colorimetric sensor for detecting, quantifying, or both detecting and quantifying, at least one analyte in a sample, the sensor including a light transparent chemochromic layer applied onto the photoactive surface of an image sensor, or attached thereto via an optic coupler, wherein the chemochromic layer comprises a chemochromic material that is optically altered when contacted with the analyte. A method for detecting at least one analyte with a colorimetric sensor.

The present invention relates to an OECT sensor (1) for determining biochemical parameters in a subject's perspiration, comprising a filament (2) coated with a first layer (3) made of a conductive polymer, wherein the ends of the filament (2) are connected to two electrodes (4, 4), wherein a first electrode (4) is grounded (V.sub.0), while a negative potential (V) is applied to the second electrode (4), the sensor (1) further comprising a control electrode (5), to which a positive potential (V+) is applied, wherein the filament (2) comprises a second layer (6) comprising an enzyme which catalyzes a transformation reaction of an analyte present in the liquid to be analyzed with generation of cations.

Among others, the present invention provides apparatus for interacting with a biological subject to detect circulating tumor cells therein, comprising one device for sending a signal to the biological subject and optionally receiving a response to the signal from the biological entity.

Techniques for measuring ion related metrics at a user's skin surface are disclosed. In one aspect, a method for operating a wearable device may involve determining, based on output of one or more ion selective field effect transistor sensors, various physiological conditions such as a state of hydration, a state of skin health, or the cleanliness of the wearable device or an associated garment.

Techniques for measuring ion related metrics at a user's skin surface are disclosed. In one aspect, a method for operating a wearable device may involve determining, based on output of one or more ion selective field effect transistor sensors, various physiological conditions such as a state of hydration, a state of skin health, or the cleanliness of the wearable device or an associated garment.