Intravascular devices, systems, and methods are disclosed. In some embodiments, a medical imaging system for imaging vasculature of a patient is provided. The imaging system includes a console that has one or more processors with a medical imaging system interface running thereon, an acquisition card in communication with the one or more processors and in communication with a patient interface module (PIM), and an intravascular imaging component in communication with the PIM and disposed on a distal end of a flexible elongate member. The medical imaging system interface provides a plurality of settings groups for selection by a user, each of the settings groups having pre-acquisition parameters and post-acquisition parameters that are optimal for imaging a desired viewing target within the vasculature. Associated methods and computer-readable media are provided.

Method and apparatus can be provided according to an exemplary embodiment of the present disclosure. For example, with at least one first section of an optical enclosure, it is possible to provide at least one first electro-magnetic radiation. In addition, with at least one second section provided within the enclosure, it is possible to cause, upon impact by the first radiation, a redirection of the first radiation to become at least one second radiation. Further, with at least one third section of the optical enclosure, it is possible to cause at least one second radiation to be provided to a tissue. For example, the redirection of the first radiation causes, at least approximately, a uniform optical illumination on of a surface of the tissue.

Method and apparatus can be provided according to an exemplary embodiment of the present disclosure. For example, with at least one first section of an optical enclosure, it is possible to provide at least one first electro-magnetic radiation. In addition, with at least one second section provided within the enclosure, it is possible to cause, upon impact by the first radiation, a redirection of the first radiation to become at least one second radiation. Further, with at least one third section of the optical enclosure, it is possible to cause at least one second radiation to be provided to a tissue. For example, the redirection of the first radiation causes, at least approximately, a uniform optical illumination on of a surface of the tissue.

A surgical system includes a tubular shaft having a wall defining an outer surface and an inner surface disposed about an inner space, the tubular shaft having a proximal end and a distal end. The surgical system also includes at least one light emitter and at least one light sensor disposed at the distal end of the tubular shaft, and one or more leads or conductors electrically coupled to the at least one light emitter or the at least one light sensor. The one or more leads may be disposed in clearances defined by first and second jaws. Alternatively or in addition, the one or more conductors may be formed on a flexible substrate, and the flexible substrate may have a deformed state in which the substrate is disposed in the inner space.

Corona Phase Molecular Recognition (CoPhMoRe) utilizing a template heteropolymer adsorbed onto and templated by a nanoparticle surface to recognize a specific target analyte can be used for macromolecular analytes, including proteins.

A process for calibrating a glucose sensor under sterile conditions includes providing separate, sterile, glucose-containing calibration fluids, each having a different glucose concentration, and in turn providing these fluids to a sensing zone containing a sensing probe of a glucose sensor. Each solution is typically, in turn, propelled into the sensing zone, thus flushing out used fluid already present in the sensing zone. The process provides rapid calibration of a glucose sensor in a sterile fashion and is therefore appropriate for point-of-use calibration.

A process for calibrating a glucose sensor under sterile conditions includes providing separate, sterile, glucose-containing calibration fluids, each having a different glucose concentration, and in turn providing these fluids to a sensing zone containing a sensing probe of a glucose sensor. Each solution is typically, in turn, propelled into the sensing zone, thus flushing out used fluid already present in the sensing zone. The process provides rapid calibration of a glucose sensor in a sterile fashion and is therefore appropriate for point-of-use calibration.

An image acquisition unit sequentially acquires a medical image. A recognition processing unit applies a recognition process to the medical image. A recognition result display determination unit determines to display or not display the result of the recognition process on a display according to blur in the medical image. A display control unit controls the display of the recognition process according to the determination by the recognition result display determination unit.

A sensor implanted in tissues and including a sensing layer is fabricated by mixing the signal transduction enzyme with non-reactive components including buffer salts and fillers, and spin coating the enzyme onto a substrate. The signal transduction enzyme is crosslinked by introducing the coated substrate in a vacuum chamber. In the chamber, a crosslinker evaporates and is deposited onto the enzyme, therefore crosslinking the enzyme.

A sensor implanted in tissues and including a sensing layer is fabricated by mixing the signal transduction enzyme with non-reactive components including buffer salts and fillers, and spin coating the enzyme onto a substrate. The signal transduction enzyme is crosslinked by introducing the coated substrate in a vacuum chamber. In the chamber, a crosslinker evaporates and is deposited onto the enzyme, therefore crosslinking the enzyme.