Independent component analysis may be performed on a plurality of detected electronic signals to separate signals within the detected electronic signals that are contributed by different sources. Each of the plurality of detected electronic signals may be received from a separate detector and may correspond to a detected optical signal emanating from a pregnant mammal's abdomen and a fetus contained therein. The detected optical signals may correspond to light that is projected into the pregnant mammal's abdomen from a light source. The separated signals may be analyzed to determine a separated signal that corresponds to light incident upon the fetus, which may be analyzed to determine a fetal hemoglobin oxygen saturation level of the fetus. An indication of the fetal hemoglobin oxygen saturation level may then be provided to the user.

Independent component analysis may be performed on a plurality of detected electronic signals to separate signals within the detected electronic signals that are contributed by different sources. Each of the plurality of detected electronic signals may be received from a separate detector and may correspond to a detected optical signal emanating from a pregnant mammal's abdomen and a fetus contained therein. The detected optical signals may correspond to light that is projected into the pregnant mammal's abdomen from a light source. The separated signals may be analyzed to determine a separated signal that corresponds to light incident upon the fetus, which may be analyzed to determine a fetal hemoglobin oxygen saturation level of the fetus. An indication of the fetal hemoglobin oxygen saturation level may then be provided to the user.

A method for detecting fetal blood oxygen saturation, including: using at least two detection light of different wavelengths, to irradiate a fetus in an examined pregnant woman's abdomen in a time-sharing manner and acquiring first photoplethysmography signals corresponding to the abdomen under irradiation of the respective wavelengths of detection light, and to irradiate a detection site except the examined pregnant woman's abdomen in a time-sharing manner and acquiring second photoplethysmography signals corresponding to the detection site under irradiation of the respective wavelengths of the detection light; determining a target photoplethysmography signal of the fetus that corresponds to the detection light of each wavelength, according to the first photoplethysmography signals and the second photoplethysmography signals that correspond to the detection light of each wavelength; and determining the fetal blood oxygen saturation, according to respective target photoplethysmography signals determined.

A method for detecting fetal blood oxygen saturation, including: using at least two detection light of different wavelengths, to irradiate a fetus in an examined pregnant woman's abdomen in a time-sharing manner and acquiring first photoplethysmography signals corresponding to the abdomen under irradiation of the respective wavelengths of detection light, and to irradiate a detection site except the examined pregnant woman's abdomen in a time-sharing manner and acquiring second photoplethysmography signals corresponding to the detection site under irradiation of the respective wavelengths of the detection light; determining a target photoplethysmography signal of the fetus that corresponds to the detection light of each wavelength, according to the first photoplethysmography signals and the second photoplethysmography signals that correspond to the detection light of each wavelength; and determining the fetal blood oxygen saturation, according to respective target photoplethysmography signals determined.

Light reflected from a pregnant woman's abdomen and fetus contained therein that has been received by a detector and converted into a reflected electronic signal may be received by a processor. A portion of the reflected electronic signal that is reflected from the fetus may be isolated and the isolated portion of the reflected electronic signal may be analyzed to determine a fetal hemoglobin oxygen saturation level of the fetus. The isolation may be achieved by synchronizing the reflected electronic signal with a fetal heartbeat signal and multiplying the synchronized reflected electronic signal by the synchronized fetal heartbeat signal.

Light reflected from a pregnant woman's abdomen and fetus contained therein that has been received by a detector and converted into a reflected electronic signal may be received by a processor. A portion of the reflected electronic signal that is reflected from the fetus may be isolated and the isolated portion of the reflected electronic signal may be analyzed to determine a fetal hemoglobin oxygen saturation level of the fetus. The isolation may be achieved by synchronizing the reflected electronic signal with a fetal heartbeat signal and multiplying the synchronized reflected electronic signal by the synchronized fetal heartbeat signal.

A plurality of sets of simulated optical inputs that is simulated to travel through an animal model of tissue, thereby generating simulated light transmission data, and corresponding oximetry vales may be used to train a simulated fetal oximetry model to predict, or calculate, oximetry values for subsequently received sets of simulated light transmission data. The simulated fetal oximetry model may be adapted to train an in vivo fetal oximetry model that may be configured to predict, or calculate, fetal oximetry values for subsequently received sets of light transmission data received from an in vivo study of a pregnant mammal and her fetus.

A plurality of sets of simulated optical inputs that is simulated to travel through an animal model of tissue, thereby generating simulated light transmission data, and corresponding oximetry vales may be used to train a simulated fetal oximetry model to predict, or calculate, oximetry values for subsequently received sets of simulated light transmission data. The simulated fetal oximetry model may be adapted to train an in vivo fetal oximetry model that may be configured to predict, or calculate, fetal oximetry values for subsequently received sets of light transmission data received from an in vivo study of a pregnant mammal and her fetus.

In one aspect, an apparatus for monitoring a physiological condition of a patient is disclosed. The apparatus includes a body having an attachment portion configured to be inserted into the skin of a patient to affix the body to the patient. The apparatus includes a sensor coupled to the body that is configured to generate sensor data corresponding to a physiological condition of the patient when the body is secured to the skin of the patient. The apparatus further includes a reference sensor that is remote from the sensor coupled to the body and is configured to engage an outer surface of skin to generate reference data against which the sensor data is compared.

The present invention relates to a device for monitoring a concentration of an analyte in a foetus. The device comprises a biosensor for electrochemically measuring a concentration of an analyte in the foetus, a protrusion configured to be at least partially inserted into foetal tissue, and a device body supporting the biosensor and the protrusion. The device is configured such that when the device body contacts the surface area of the foetal tissue, the device body can be anchored to the foetal tissue and the protrusion can be inserted into the tissue so that the reactive substance of the biosensor electrochemically reacts with the analyte in the foetal tissue and in response to the electrochemical reaction the electrode of the biosensor detects an electronic signal, a strength of the electronic signal being indicative of the concentration of the analyte.