Various embodiments of the present disclosure describe a diversion device that traps an initial flow of blood in a diversion chamber of the diversion device. The diversion chamber may be defined, in part, by a housing shell, a housing base, and a filter. The filter may be a porous material that allows air, but not blood, to flow through it. After the diversion chamber is filled, a subsequent flow of blood may be directed into a collection vessel through an internal conduit of the diversion device.

A system for confirmation of fluid delivery to a patient at the clinical point of use is provided. The system includes a wearable electronic device. The wearable electronic device has a housing; at least one imaging sensor associated with the housing; a data transmission interface; a data reporting accessory for providing data to the user; a microprocessor for managing the at least one imaging sensor, the data transmission interface, and the data reporting accessory; and a program for acquiring and processing images from the at least one imaging sensor. The system further includes a fluid delivery apparatus; and one or more identification tags attached to or integrally formed with the fluid delivery apparatus. The program processes an image captured by the at least one imaging sensor to identify the one or more identification tags and acquires fluid delivery apparatus information from the one or more identification tags.

The present invention generally relates to systems and methods for delivering and/or receiving a substance or substances such as blood from subjects. In one aspect, the present invention is directed to devices and methods for receiving or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a substance transfer component (for example, one or more needles or microneedles) and a reduced pressure or vacuum chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some embodiments, the device may contain a “snap dome” or other deformable structure, which may be used, at least in part, to urge or move needles or other suitable substance transfer components into the skin of a subject. In some cases, for example, the device may contain a flexible concave member and a needle mechanically coupled to the flexible concave member such that the needle may be urged or moved into the skin using the flexible concave member. Other aspects of the present invention are directed at other devices for receiving blood (or other bodily fluids, e.g., interstitial fluid), kits involving such devices, methods of making such devices, methods of using such devices, and the like.

An instrument advancement device includes a housing comprising a fluid path, a distal end, and a proximal end, an instrument disposed within the housing, an advancement element, where in response to movement of the advancement element with respect to the housing, the instrument is configured to advance distal to the distal end of the housing, a small sample dispense device connected to the proximal end of the housing, and a blood collection device connected to a proximal end of the small sample dispense device. The blood collection device is configured to receive an evacuated blood collection container, where the small sample dispense device is detachable from the housing and configured to dispense a blood sample.

An instrument advancement device may include a housing comprising a distal end and a proximal end; an instrument disposed within the housing; an advancement element, wherein in response to movement of the advancement element with respect to the housing, the instrument is configured to advance distal to the distal end of the housing, and a blood sample collection tube inserted into the distal end of the housing, wherein the blood sample collection tube is configured to receive a small volume blood sample.

A biological fluid collection device that receives a sample and provides flow-through blood stabilization technology and a precise sample dispensing function for point-of-care and near patient testing applications is disclosed. A biological fluid collection device of the present disclosure is able to effectuate distributed mixing of a sample stabilizer within a blood sample and dispense the stabilized sample in a controlled manner. In this manner, a biological fluid collection device of the present disclosure enables blood micro-sample management, e.g., passive mixing with a sample stabilizer and controlled dispensing, for point-of-care and near patient testing applications.

The invention relates to a blood pricking head (8) for a mechatronic assembly such as a robot-controlled arm of an automatic or semi-automatic blood collection machine configured to enable movement of the mechatronic assembly below the limb of a patient, the pricking head comprising: a frame (10) provided with removable attachment means (11) that can be moved from the frame to the mechatronic assembly; a holder (12) for collection needles, means (16) for linearly moving the needle holder; a motorised device (25) for fluidically linking the needle mounted on the needle holder with a collection tube; and an electromechanical device (21, 22) configured to enable, on command, withdrawal of the pricking needle from the patient's arm.

A package for a needle assembly includes a tray defining a compartment in a first configuration for receiving the needle assembly. The tray can be reconfigured in a second configuration to form a holder configured to hold the needle assembly during fluid collection.

A syringe-based device includes a housing, a pre-sample reservoir, and an actuator. The housing defines an inner volume between a substantially open proximal end portion and a distal end portion that includes a port couplable to a lumen-defining device. The pre-sample reservoir is fluidically couplable to the port to receive and isolate a first volume of bodily fluid. The actuator is at least partially disposed in the inner volume and has a proximal end portion that includes an engagement portion and a distal end portion that includes a sealing member. The engagement portion is configured to allow a user to selectively move the actuator between a first configuration such that bodily fluid can flow from the port to the pre-sample reservoir, and a second configuration such that bodily fluid can flow from the port to a sample reservoir defined at least in part by the sealing member and the housing.