A teething apparatus includes a water-resistant housing containing a controller and a power source and communication means and a plurality of sensors in communication with the surface of the housing arranged and configured to detect at least pH and at least one volatile organic compound. Each of the plurality of sensors is in data communication with the controller and the controller is capable of communication with an external device via communication means. The apparatus may be a component of a larger system and may be used in a method including the steps of providing a teething apparatus to an oral cavity of an infant, establishing a data connection between the teething apparatus and a remote device, and relaying information from the teething apparatus to the remote device, the information comprising the qualitative measurement of one or more volatile organic compounds and the quantitative value of pH in the oral cavity.

The present disclosure provides an oral data collection device comprising a mouthguard and at least two sensors, a medical analytics system comprising the device, and methods of using the device and system to provide a personalized treatment protocol, stage a health condition, measure a response to therapy, phenotype for selection to participate in drug trials, measure stability of an anatomical structure, or predict a rate of change of a health condition in a subject in need thereof.

Intraoral neuromodulation for the treatment clinical conditions such as, e.g., dysphagia, migraines, or speech problems can be achieved with a neuromodulation system that includes an intraoral neural stimulator, e.g., integrated into a wearable device to be positioned in the oral cavity, that is controlled based on one or more measured signals associated with an intraoral organ or nerve related to the clinical condition.

A liquid mixture obtained by mixing a bolus and an adjusting agent is poured into a tray-shaped container, and during spreading of bolus particles constituting the bolus along the bottom surface, the tray-shaped container is placed in a first inclined state in which the bottom surface is inclined by increasing the height of one edge side in the left-right direction of the tray-shaped container relative to the other edge side thereof, and the liquid mixture in the tray-shaped container is moved toward the other edge side, after which the tray-shaped container is placed in a second inclined state in which the bottom surface is inclined in the reverse direction by reducing the height of one edge side of the tray-shaped container relative to the other edge side thereof, after which the bottom surface is placed in a horizontal state, and the bolus particles are thereby spread.

The invention relates to devices, systems and methods exploiting capacitive means for monitoring and analysing teeth-related parameters in a subject, such as the dental occlusion profile and/or the load/force applied upon clenching. The device comprises a body such as a bite fork or bite splint, capacitive sensor(s) incorporated within a soft substrate reversibly deformable once bitten by a subject and a micro-controller unit. The teeth contact points and forces applied upon occlusion are measured via the sensors, delivered to and re-elaborated by the micro-controller unit and possibly sent and visualized in a graphical/numerical fashion on e.g. a display screen.

A system and method are described for assessing muscle parameters (e.g., force(s) exerted, force dynamics, strength, voluntary muscle movement, etc.) in a diagnostic or therapeutic environment. The muscle parameter assessment system includes a force-gauging device and a computing device. The force-gauging device includes at least one pressure-sensing component (e.g., transducer, pressure sensor, etc.) configured to respond to a force applied by a subject and produce one or more output signals. The force-gauging device can further include electronic circuitry configured to convert the output signals into data indicative of a muscle parameter. The computing device is configured to build a muscle assessment protocol based on one or more patient characteristics and/or user input. The computing device is further configured to execute one or more muscle assessments via the force-gauging device, receive data from the force-gauging device, and determine one or more muscle measurements for a subject.

An apparatus for evaluating the tongue strength and coordination of a subject includes an intermediate device such as a lever which is pivotably attached to a coupling device and extends into a cavity of a nipple element. The lever is detached from the nipple and pivotable in response to deformation of the nipple element by a tongue force exerted on the nipple element by a subject during a suck-swallow-breathe sequence. The coupling device includes a sensing device to wirelessly transmit sensor outputs to a mobile device paired to the sensing device. The sensing device includes at least one sealed chamber defined by a membrane and a sensor. In one example, a first membrane and sensor senses pressure change in a fluid in the apparatus, and a second membrane and sensor is actuated by the intermediate device to sense deformation of the nipple element. A method using the apparatus is provided.

This invention presents an intraoral device for generation of contact perception between teeth, the device being configured for application to the upper or lower dental arch of a user and comprising a contact means (20, 20′) configured to be associated with at least a portion of one to four posterior teeth (D1) of the upper or lower dental arch, the device (10) being configured to generate a perception of contact to the user upon the contact between the contact means (20, 20′) and at least a portion of the opposing arch to at least a portion of one to four posterior teeth (D1), offering the option of an accessible intraoral device for practical use to the user, and that does not impair the mouth functions of the user during its use in the waking period. This invention further comprises a method of applying the device which allows the user to apply the device without assistance of a skilled professional, and a method for determining the thickness of the aforesaid device.

The invention relates to an adaptation system (500), comprising a mouthpiece (10), configured to be positioned in a mouth of a person, and an external sensoring device (20). The external sensoring device (20) is configured to be positioned at the person, wherein the external sensoring device (20) comprises at least one sensor (22) configured to sense at least one measurable quantity when the mouthpiece (10) is positioned in the person's mouth and the external sensoring device (20) is positioned at the person. Further, the adaptation system (500) comprises an analysis device (30) configured to determine a compliance of the adaptation system and/or to determine an orientation of an upper jaw (100) and a lower jaw (200) to each other derived from the at least one sensed measurable quantity.

Embodiments of the present invention provide an oral device. According to one embodiment of the present invention, a mouthpiece suitable to detachably engage teeth of an upper jaw is provided. The mouthpiece comprises an adhesive layer configured to attach a hermetically sealed chamber to the mouthpiece. The hermitically sealed chamber fits within a concave space created by the mouthpiece. The hermitically sealed chamber comprises two layers and embedded between those two layers are a pressure sensor, a microphone, an optical sensor, a temperature sensor, a communications module, a storage enclosure, and a biosensor. Each of the pressure sensor, the microphone, the optical sensor, the temperature sensor, the communications module, the storage enclosure, and the biosensor are operably connected within the hermetically sealed chamber.