A vapor cell which can increase the S/N ratio of light as a signal and has high accuracy and a vapor cell manufacturing method are provided. The vapor cell includes: a reflection space (14) provided so as to be able to store a gas containing an alkali metal atom; and an incident light reflection surface, an in-plane reflection portion (17), and an emission light reflection surface provided inside the reflection space (14). The incident light reflection surface has an elevation angle of 45° from an optical path plane so that the incident light incident from a predetermined external direction is reflected in the optical path plane that is perpendicular to the incident light. The in-plane reflection portion (17) has a reflection surface that reflects the reflected light from the incident light reflection surface, the reflection surface being substantially perpendicular to the optical path plane so that the reflected light from the incident light reflection surface is reflected in the optical path plane once or multiple times. The emission light reflection surface has an elevation angle 45° from the optical path plane so that the reflected light from the in-plane reflection portion (17) is reflected in a direction substantially perpendicular to the optical path plane and an emission light is emitted to the outside.

A shielding arrangement for a magnetoencephalography (MEG) system includes a passively shielded enclosure having a plurality of walls defining the passively shielded enclosure, each of the plurality of walls including passive magnetic shielding material to reduce an ambient background magnetic field within the passively shielded enclosure; a vestibular wall extending from a first vertical wall to define, and at least partially separate, a vestibular area of the passively shielded enclosure adjacent the doorway and a user area of the passively shielded enclosure; and active shield coils distributed within the passively shielded enclosure and configured to further reduce the ambient background magnetic field within the user area of the passively shielded enclosure.

A shielding arrangement for a magnetoencephalography (MEG) system includes a passively shielded enclosure having a plurality of walls defining the passively shielded enclosure, each of the plurality of walls including passive magnetic shielding material to reduce an ambient background magnetic field within the passively shielded enclosure; a vestibular wall extending from a first vertical wall to define, and at least partially separate, a vestibular area of the passively shielded enclosure adjacent the doorway and a user area of the passively shielded enclosure; and active shield coils distributed within the passively shielded enclosure and configured to further reduce the ambient background magnetic field within the user area of the passively shielded enclosure.

A device, system, and method for facilitating a sleep cycle in a subject during a pandemic or peri COVID vaccination period, comprising determining a current awake or sleep stage of a person; automatically defining a desired sleep cycle pattern, dependent on the current awake or sleep stage of the person; generating an audio or optical stimulation pattern by an automated processor; and entraining brainwaves of the brain of the person with the stimulation pattern corresponding to the desired sleep cycle pattern, to thereby induce a sleep cycle in the person according to the sleep cycle pattern. When sleep patterns are normalized, a SARS-Cov-2 vaccination may be administered to the person.

The exemplified technology facilitates de-noising of magnetic field-sensed signal data (e.g., of an electrophysiological event) using signal reconstruction processes that fuse the magnetic field-sensed signal data with another sensed signal data (e.g., voltage gradient signal data) captured simultaneously with the magnetic field-sensed signal data. To this end, the purely algorithmic processing technique beneficially facilitates removal and/or filtering of noise from a sensor lead of a noisy captured source and rebuilds the signal for that lead from information simultaneously obtained from other leads of a different source. In some embodiments, a data are fused via a sparse approximation operation that uses candidate terms based on Van der Pol differential equations.

The exemplified technology facilitates de-noising of magnetic field-sensed signal data (e.g., of an electrophysiological event) using signal reconstruction processes that fuse the magnetic field-sensed signal data with another sensed signal data (e.g., voltage gradient signal data) captured simultaneously with the magnetic field-sensed signal data. To this end, the purely algorithmic processing technique beneficially facilitates removal and/or filtering of noise from a sensor lead of a noisy captured source and rebuilds the signal for that lead from information simultaneously obtained from other leads of a different source. In some embodiments, a data are fused via a sparse approximation operation that uses candidate terms based on Van der Pol differential equations.

The present invention is designed such that, even when inward currents cannot be calculated properly, it is possible to generate current waveforms that can appropriately evaluate the action of a target body tissue by calculating currents that are equivalent to inward currents. A biomagnetic field measurement system includes circuitry and a memory storing executable instructions which, when executed by the circuitry, cause the circuitry to: based on current components extracted from current signals calculated from a biomagnetic field signal, add up current waveforms of current components along a conduction pathway of an action current in a body tissue that is targeted for evaluation, and generate a current waveform for evaluating an intra-cellular current flowing in the conduction pathway, locations of the current components of the added current waveforms being predetermined set distances apart on the conduction pathway, in front of and behind a location of interest on the conduction pathway.

A device for stimulating neurons that includes a stimulation unit that applies mechanically tactile and/or thermal stimuli to the body surface of a patient that stimulate neurons with a pathologically synchronous and oscillatory neural activity. The device includes a measuring unit that records measurement signals of neural activity of the stimulated neurons, and a controller that controls the stimulation unit and analyzes the measurement signals. The controller actuates the stimulation unit to scan at least one part of the body surface of the patient along a path and thereby periodically applies stimuli and also selects two regions or more regions on the patient's body surface along the path where the phase synchronization between the periodic application of the stimuli and the neural activity of the stimulated neurons have a local maximum using the measurement signals. The stimuli are then applied in a delayed manner in the two regions.

A device for stimulating neurons that includes a stimulation unit that applies mechanically tactile and/or thermal stimuli to the body surface of a patient that stimulate neurons with a pathologically synchronous and oscillatory neural activity. The device includes a measuring unit that records measurement signals of neural activity of the stimulated neurons, and a controller that controls the stimulation unit and analyzes the measurement signals. The controller actuates the stimulation unit to scan at least one part of the body surface of the patient along a path and thereby periodically applies stimuli and also selects two regions or more regions on the patient's body surface along the path where the phase synchronization between the periodic application of the stimuli and the neural activity of the stimulated neurons have a local maximum using the measurement signals. The stimuli are then applied in a delayed manner in the two regions.

A method of operating an optically pumped magnetometer (OPM) includes directing a light beam through a vapor cell of the OPM including a vapor of atoms; applying RF excitation to cause spins of the atoms to precess; measuring a frequency of the precession; for each of a plurality of different axes relative to the vapor cell, directing a light beam through the vapor cell, applying a magnetic field through the vapor cell along the axis, applying RF excitation to cause spins of the atoms to precess, and measuring a frequency of the precession in the applied magnetic field; determining magnitude and components of an ambient background magnetic field along the axes using the measured frequencies; and applying a magnetic field based on the components around the vapor cell to counteract the ambient background magnetic field to facilitate operation of the OPM in a spin exchange relaxation free (SERF) mode.