An apparatus for measuring magnetic fields from a subject's organ comprises a plurality of unshielded magnetometers in a three-dimensional arrangement. A respective pair of magnetometers, in the plurality of magnetometers, has a respective known separation. Each magnetometer in the plurality of magnetometers is configured to simultaneously detect a biomagnetic field from at least a portion of the subject's organ and a background magnetic field and output a signal indicative of the detected biomagnetic field and the background magnetic field.

A current source estimation time determination method includes: determining an analysis interval in which a characteristic waveform is obtained with respect to one or more pieces of waveform data acquired by a sensor; estimating a current source with respect to a signal in the analysis interval determined at the determining; detecting a continuous movement interval in which the current source continuously moves in the analysis interval, using coordinates of the current source estimated at the estimating; and determining a single current source estimation time from the continuous movement interval detected at the detecting.

A current source estimation time determination method includes: determining an analysis interval in which a characteristic waveform is obtained with respect to one or more pieces of waveform data acquired by a sensor; estimating a current source with respect to a signal in the analysis interval determined at the determining; detecting a continuous movement interval in which the current source continuously moves in the analysis interval, using coordinates of the current source estimated at the estimating; and determining a single current source estimation time from the continuous movement interval detected at the detecting.

Methods are for determining whether a subject who does not present clinical symptoms associated with Alzheimer's disease (AD) or mild cognitive impairment (MCI) is in a process of developing AD or MCI, or at risk for developing post-anesthesia delirium or cognitive dysfunction, by detecting the presence of epileptiform spikes in the brain of the subject during diagnostic anesthesia. Additional methods are for preventing, reducing likelihood of, or treating AD or MCI, or post-anesthesia delirium or cognitive dysfunction.

Methods are for determining whether a subject who does not present clinical symptoms associated with Alzheimer's disease (AD) or mild cognitive impairment (MCI) is in a process of developing AD or MCI, or at risk for developing post-anesthesia delirium or cognitive dysfunction, by detecting the presence of epileptiform spikes in the brain of the subject during diagnostic anesthesia. Additional methods are for preventing, reducing likelihood of, or treating AD or MCI, or post-anesthesia delirium or cognitive dysfunction.

A helmet-like medical diagnostic apparatus that is fixed or worn has motorized gimbals that automatically swivel to positions around a patient's head. An end effector extends radially from the gimbals toward the head to place a coil or other directional sensor snugly against the scalp. A coil sensor can be part of a sensitive circuit to measure eddy currents within the brain. Accelerometers, or other tilt-measuring gauges, are compared between those on the sensor and those on the apparatus's base to determine the precise 3D orientation of the sensor when resting against the head. The orientation can compensate coil measurements, find an exact spot again, or map opposing sides of the patient's cranium, even with a fidgeting unconscious patient. The head can be scanned in its entirety, or a spot scan may be prompted from other diagnostic data.

A helmet-like medical diagnostic apparatus that is fixed or worn has motorized gimbals that automatically swivel to positions around a patient's head. An end effector extends radially from the gimbals toward the head to place a coil or other directional sensor snugly against the scalp. A coil sensor can be part of a sensitive circuit to measure eddy currents within the brain. Accelerometers, or other tilt-measuring gauges, are compared between those on the sensor and those on the apparatus's base to determine the precise 3D orientation of the sensor when resting against the head. The orientation can compensate coil measurements, find an exact spot again, or map opposing sides of the patient's cranium, even with a fidgeting unconscious patient. The head can be scanned in its entirety, or a spot scan may be prompted from other diagnostic data.

Systems and methods for predictive glucose in accordance with embodiments of the invention are illustrated. One embodiment includes glucose management device, including a brain signal recorder, and a controller, including a processor, and a memory, the memory containing a glucose monitoring application configured to direct the processor to record a brain activity signal of a user's brain using the brain signal recorder, and decode the brain activity signal to predict future glucose levels of the patient.

A biosignal measuring device that can include at least one Super-conducting Quantum Interference Device (SQUID) array (SQA) of High Temperature Superconducting (HTS) Josephson Junctions (JJs). The HTS JJs operating parameters can be adjusted to establish an anti-peak response for the SQA, that can be at a maximum along a defined response axis, for detection of extremely small biomagnetic fields. For operation, the SQA can be maneuvered around a target area of a stationary subject that is emitting biomagnetic signals using a stand with three degrees of freedom, so that the response axis remains orthogonal to the subject target area. The device can further include a radome with an atomic layer deposition (ALD) window on the radome surface. The radome ALD surface can allow for passage of magnetic signals through the ALD window and radome, while simultaneously preventing passage of infrared radiation therethrough.

An information displaying system according to an embodiment of the present disclosure includes a first display section configured to display a time axis of detected signals along a first direction, a second display section configured to display a plurality of signal waveforms based on the detected signals in parallel so that the signal waveforms are arranged side by side in a second direction different from the first direction, and a controller configured to control the first display section and the second display section. When, in the second display section, a location on at least one of the plurality of the signal waveforms or near the at least one of the plurality of the signal waveforms is designated, the controller highlights the designated location, and displays a designated result on a time location in the first display section corresponding to the designated location.