Provided are a biomagnetic measuring device and a control method for a biomagnetic measuring device that can measure biomagnetism more accurately. A biomagnetic measuring device according to the present invention includes: a first magnetic sensor and a second magnetic sensor that each include a cell having an internal space, and detect biomagnetism utilizing an optical pumping action by plasma generated in the cell; a plasma generator that supplies electric power for generating plasma in the internal space of each of the cells included in the first magnetic sensor and the second magnetic sensor; and a power supply controller that controls the plasma generator to generate plasma in the first magnetic sensor from a first start time to a first end time and generate plasma in the second magnetic sensor from a second start time after the first start time to a second end time after the first end time.

Example systems, methods, and apparatus are provided for using data collected from the responses of an individual with the computerized tasks of a cognitive platform to derive performance metrics as an indicator of cognitive abilities, and applying predictive models to generate an indication of a neurodegenerative condition. The example systems, methods, and apparatus also can be configured to adapt the computerized tasks to enhance the individual's cognitive abilities, and for using data collected from the responses of an individual with the adapted computerized tasks to derive performance metrics and applying predictive models to generate the indication of neurodegenerative condition.

Apparatus for applying Transcranial Magnetic Stimulation (TMS) to a patient, wherein the apparatus comprises: a head mount for disposition on the head of a patient; and a plurality of magnet assemblies for releasable mounting on the head mount, wherein each of the magnet assemblies comprises a magnet for selectively providing a rapidly changing magnetic field capable of inducing weak electric currents in the brain of a patient so as to modify the natural electrical activity of the brain of the patient; wherein the number of magnet assemblies mounted on the head mount, their individual positioning on the head mount, and their selective provision of a rapidly changing magnetic field is selected so as to allow the spatial, strength and temporal characteristics of the magnetic field to be custom tailored for each patient, whereby to provide patient-specific TMS therapy, to assist in diagnosis or to map out brain function in neuroscience research. In one preferred form of the invention, each of the magnet assemblies comprises a magnet for selectively providing a rapidly changing magnetic field of at least 500-600 Tesla/second corresponding to a magnet movement speed of no less than 400 Hertz.

A method for detecting evidence of a stroke in a patient may involve securing a volumetric integral phase-shift spectroscopy (VIPS) device to the patient's head, transmitting a first signal from a first transmitter of the VIPS device through a left hemisphere of the patient's brain to a receiver of the VIPS device, transmitting a second signal from a second transmitter of the VIPS device through a right hemisphere of the patient's brain to the receiver, and detecting the evidence of the stroke, with the VIPS device.

The present invention introduces a method for adjusting interference signal estimates provided by multichannel biomagnetic field measurements. A so-called Signal Space Separation method (SSS) is applied in the calculatory analysis of the measurement signals, providing for the division of the sources causing the fields in objects of interest and external interferences. When the signal basis representing the interferences has been estimated, this interference signal estimate is adjusted by measuring the fields without the object to be measured and without changing the sensor assembly. Interference components obtained in this manner are analyzed in such a way as to include only the most significant interference components. An adjusted interference subspace is formed, by means of which signal processing and the analysis of the useful signals can be continued.

The gradiometers of the present invention are developed by applying GSR sensors to have the detectability of magnetic field same to that of SQUID without a cryogenic temperature retainer. Plural GSR elements are fitted on two parallel convex line guides of the gradiometer board using two parallel concave line guides of the GSR element board to keep the parallel among wires direction of GSR elements perfectly and to cancel the outside magnetic field noise without a magnetic shield room.

Electrical non-invasive brain stimulation (NIBS) delivers weak electrical currents to the brain via electrodes that are affixed to the scalp. NIBS can excite or inhibit the brain in areas that are impacted by that electrical current during and for a short time following stimulation. Electrical NIBS can be used to change brain structure in terms of increasing white matter integrity as measured by diffusion tensor imaging. Together the electrical NIBS can induce changes in brain structure and function. The present methods and devices are adaptable to and configurable for facilitating the enhancement of brain performance, and the treatment of neurological diseases and tissues. The present methods and devices are advantageously designed to utilize modern electrodes deployed with, inter alia, various spatial arrangements, polarities, and current strengths to target brain areas or networks to thereby enhance performance or deliver therapeutic interventions.

The present invention provides a method for identifying images of brain function. In the beginning, choosing one of the brain data collected by multichannel scalp EEG/MEG, and using a mode decomposition method to obtain a plurality of intrinsic mode functions for each brain data, transforming the intrinsic mode functions (IMFs) in the same frequency scale into a plurality of source IMFs across the cerebral cortex by a source reconstruction algorithm, and classifying each source IMF in the same frequency scale into a plurality of frequency regions corresponding to the different brain sites. Then, repeatedly choosing a source IMF, and obtaining an amplitude envelope line through each absolution value of the source IMF. Further to obtain a plurality of source first-layer amplitude IMFs decomposed from the function of the amplitude envelope line by the mode decomposition method. Until obtaining the source first-layer amplitude IMFs from each source IMF, classifying each source first-layer amplitude IMF in the same amplitude frequency scale into a plurality of amplitude frequency regions corresponding to the different brain sites. In the end, a brain amplitude modulation spectrum is provided for analyzing the relationship between each frequency region and each amplitude frequency region.

In a method for storing and recalling stored data, data to be stored is received and a first brain activity information from a user is received. The first brain activity is hashed to generate a first brain activity information hash value. The data is stored within a database and indexed. The indexing is done according to the first brain activity information hash value. The stored data is recalled when a request to recall the stored data is received along with a second brain activity information from a user. The received second brain activity is hashed to generate a second brain activity information hash value. The second brain activity information hash value is used to identify a location of the stored data, within the database, based on the indexing, by matching the second brain activity information hash value to the first brain activity information hash value. The stored data is then retrieved based on the identified location.

A mobile user borne brain activity data and surrounding environment data correlation system comprising a brain activity sensing subsystem, a recording subsystem, a measurement computer subsystem, a user sensing subsystem, a surrounding environment sensing subsystem, a correlation subsystem, a user portable electronic device, a non-transitory computer readable medium, and a computer processing device. The mobile user borne system collects and records brain activity data and surrounding environment data and statistically correlates and processes the data for communicating the data into a recipient biological, mechanical, or bio-mechanical system.