A system for measuring magnetic fields from a subject's organ comprises a plurality of unshielded magnetometers in a three-dimensional arrangement and an electromagnetic source. The system is configured to simultaneously collect, via each magnetometer of the plurality of magnetometers, (i) a biomagnetic field from at least a portion of the subject's organ, (ii) an electromagnetic signal from the electromagnetic source, and (iii) a background magnetic field. The system is configured to synchronize a plurality of magnetic signals collected by the plurality of magnetometers according to the electromagnetic signal from the electromagnetic source. The system is configured to output a signal indicative of the collected biomagnetic field and the background magnetic field in accordance with the synchronizing. The system is configured to operate without magnetic shielding.

A system for measuring magnetic fields from a subject's organ comprises a plurality of unshielded magnetometers in a three-dimensional arrangement and an electromagnetic source. The system is configured to simultaneously collect, via each magnetometer of the plurality of magnetometers, (i) a biomagnetic field from at least a portion of the subject's organ, (ii) an electromagnetic signal from the electromagnetic source, and (iii) a background magnetic field. The system is configured to synchronize a plurality of magnetic signals collected by the plurality of magnetometers according to the electromagnetic signal from the electromagnetic source. The system is configured to output a signal indicative of the collected biomagnetic field and the background magnetic field in accordance with the synchronizing. The system is configured to operate without magnetic shielding.

Methods using measuring alpha activity in the brain are provided for the detection and/or diagnosis of a mild traumatic brain injury in a subject. The methods comprise measuring an alpha activity in the brain of a subject, wherein an increase in the alpha activity in the brain of the subject compared to control subjects without a brain injury or to a baseline of the subject is indicative of the subject having the mild traumatic brain injury. The alpha activity may be measured when the subject is in a resting state. The methods may further comprise administering a therapy such as a pain or headache medication to the subject with a mild traumatic brain injury.

Methods using measuring alpha activity in the brain are provided for the detection and/or diagnosis of a mild traumatic brain injury in a subject. The methods comprise measuring an alpha activity in the brain of a subject, wherein an increase in the alpha activity in the brain of the subject compared to control subjects without a brain injury or to a baseline of the subject is indicative of the subject having the mild traumatic brain injury. The alpha activity may be measured when the subject is in a resting state. The methods may further comprise administering a therapy such as a pain or headache medication to the subject with a mild traumatic brain injury.

Provided herein are, inter alia, methods for identifying subjects suffering from depression that will respond to treatment with an antidepressant.

Provided herein are, inter alia, methods for identifying subjects suffering from depression that will respond to treatment with an antidepressant.

Provided herein are, inter alia, methods for identifying subjects suffering from depression that will respond to treatment with an antidepressant.

Provided herein are, inter alia, methods for identifying subjects suffering from depression that will respond to treatment with an antidepressant.

A method for predicting a development level difference of language and communication capability normality of a healthy infant or toddler. The method comprises obtaining electroencephalogram (EEG) or magnetoencephalogram (MEG) waveform data of a healthy infant or toddler caused by external auditory stimulus; obtaining, from the EEG or MEG waveform data, quantitative data that represents measurement index data of a central nervous system caused by the external auditory stimulus; and using a data set to train a machine learning classifier, so as to obtain a prediction result. Further provided are a relevant tool and an integrated system.

A helmet-like medical diagnostic apparatus that is fixed or worn has motorized gimbals that automatically swivel to positions around a patient's head. An end effector extends radially from the gimbals toward the head to place a coil or other directional sensor snugly against the scalp. A coil sensor can be part of a sensitive circuit to measure eddy currents within the brain. Accelerometers, or other tilt-measuring gauges, on the sensor determine the precise 3D orientation of the sensor when resting against the head. The orientation can compensate coil measurements, find an exact spot again, or map opposing sides of the patient's cranium, even with a fidgeting unconscious patient. The head can be scanned in its entirety, or a spot scan may be prompted from other diagnostic data.