The pulsed pump magnetometer (PPM) is a new type of magnetometer with much higher dynamic range, linearity, and sensitivity than all other types of magnetometers. These features allow more faithful subtracting and cancelling sources of magnetic noise, enabling high quality biomagnetic measurements. Using an array of PPM sensors enables high quality measurements of biomagnetic signals even in magnetically noisy, real-world conditions like medical offices. Arrays of PPM sensors improve upon pulsed magnetic gradiometers in providing higher sensitivity per sensor and superior noise rejection through noise decorrelation and covariance modeling. Arrays of PPM sensors enable localization and imaging of biomagnetic sources.

The pulsed pump magnetometer (PPM) is a new type of magnetometer with much higher dynamic range, linearity, and sensitivity than all other types of magnetometers. These features allow more faithful subtracting and cancelling sources of magnetic noise, enabling high quality biomagnetic measurements. Using an array of PPM sensors enables high quality measurements of biomagnetic signals even in magnetically noisy, real-world conditions like medical offices. Arrays of PPM sensors improve upon pulsed magnetic gradiometers in providing higher sensitivity per sensor and superior noise rejection through noise decorrelation and covariance modeling. Arrays of PPM sensors enable localization and imaging of biomagnetic sources.

An ultrasound device for modulating brain activity may include a body and components for activating the brain. Such components include ultrasound transducers. The devices are used to provide ultrasound waves to brain structures in a subject wearing a device for methods to treat traumatic brain injury, affect postural control, affect wakefulness, attention, and alertness, to provide memory control, to alter cerebrovascular hemodynamics, to minimize stress, and to reinforce behavioral actions.

An ultrasound device for modulating brain activity may include a body and components for activating the brain. Such components include ultrasound transducers. The devices are used to provide ultrasound waves to brain structures in a subject wearing a device for methods to treat traumatic brain injury, affect postural control, affect wakefulness, attention, and alertness, to provide memory control, to alter cerebrovascular hemodynamics, to minimize stress, and to reinforce behavioral actions.

The present application is drawn to a system and method, as well as method for manufacture of a device and system for determining the position and orientation of at least one magnetic field sensor comprising: a rigid structure comprising an array of at least five electromagnetic coils; at least one wire that connects to and powers the electromagnetic coils; wherein the placement and orientation of the electromagnetic coils on the rigid structure are predetermined; wherein the electromagnetic coils, each having a predefined magnetic moment per unit current, are constructed with a printed circuit board (PCB) comprising at least one conductive layer; and wherein the system is configured such that a stray magnetic field emanating from the at least one, as measured at the location of the at least one magnetic field sensor, generates substantially lower magnetic field intensity than that produced by each of the at least five electromagnetic coils.

The present application is drawn to a system and method, as well as method for manufacture of a device and system for determining the position and orientation of at least one magnetic field sensor comprising: a rigid structure comprising an array of at least five electromagnetic coils; at least one wire that connects to and powers the electromagnetic coils; wherein the placement and orientation of the electromagnetic coils on the rigid structure are predetermined; wherein the electromagnetic coils, each having a predefined magnetic moment per unit current, are constructed with a printed circuit board (PCB) comprising at least one conductive layer; and wherein the system is configured such that a stray magnetic field emanating from the at least one, as measured at the location of the at least one magnetic field sensor, generates substantially lower magnetic field intensity than that produced by each of the at least five electromagnetic coils.

The invention provides a method of determining whether a subject has a neurological dysfunction associated with a signal in a particular electroencephalogram (EEG) or magnetoencephalogram (MEG) frequency range, the method comprising: obtaining an EEG power spectrum from the subject; and obtaining a metric quantifying the magnitude of power in particular frequency range metric quantifying the power in the power spectrum in the particular frequency range, wherein the metric summarises the power in said frequency range corrected using an estimate of the power in said frequency range that is attributable to background signal that is specific to said frequency range, wherein the metric is indicative of the presence and/or severity and/or direction of a neurological dysfunction. Related methods and devices are also described.

The invention provides a method of determining whether a subject has a neurological dysfunction associated with a signal in a particular electroencephalogram (EEG) or magnetoencephalogram (MEG) frequency range, the method comprising: obtaining an EEG power spectrum from the subject; and obtaining a metric quantifying the magnitude of power in particular frequency range metric quantifying the power in the power spectrum in the particular frequency range, wherein the metric summarises the power in said frequency range corrected using an estimate of the power in said frequency range that is attributable to background signal that is specific to said frequency range, wherein the metric is indicative of the presence and/or severity and/or direction of a neurological dysfunction. Related methods and devices are also described.

Neural imaging helmets include the placement of a number of sensors, such as in a sensor array on and around the helmet. The placement and orientation of the sensors puts them close to the participant's head for best neural image capturing. As people's head size and shape varies, moving the sensors from one helmet to another can be onerous. Therefore, connecting the sensors and associated cables together allows for efficient removal and replacement of the sensors and cables. The use of sensor holders connected to another will aid in ensuring proper orientation and location, regardless of the helmet used. This will allow different sized helmets to be readily prepared for use with neural imaging devices.

Neural imaging helmets include the placement of a number of sensors, such as in a sensor array on and around the helmet. The placement and orientation of the sensors puts them close to the participant's head for best neural image capturing. As people's head size and shape varies, moving the sensors from one helmet to another can be onerous. Therefore, connecting the sensors and associated cables together allows for efficient removal and replacement of the sensors and cables. The use of sensor holders connected to another will aid in ensuring proper orientation and location, regardless of the helmet used. This will allow different sized helmets to be readily prepared for use with neural imaging devices.