To provide an in-vivo visualization device able to identify local changes in time and space.

An in-vivo visualization device according to an embodiment is provided with a current/voltage injection measurement unit which has a sensor provided with a plurality of electrodes arrangeable on a subject's skin at intervals from each other and which injects a current or applies a potential difference between each of the electrodes in a state where each of the electrodes is in contact with the skin and measures first measurement data, which is a potential difference and phase, based on a current injection/voltage measurement pattern when injecting the current, or measures second measurement data, which is a current and phase, based on a voltage injection/current measurement pattern when applying the potential difference between each of the electrodes, an image reconstruction unit which creates an electrical property distribution inside the subject's body based on the first measurement data or the second measurement data and predetermined parameters, and a region of interest identification unit that performs an identification process on the electrical property distribution to identify a region of interest and creates a post-identification electrical property distribution.

The present invention relates to an assembled, downward-pressing, multifunctional electroencephalogram (EEG) cap, at least comprising: a cap body, configured to be worn on a head of a patient, and formed by a plurality of constituent blocks, wherein each of the constituent blocks comprises a first unit and a second unit that carry extracranial electrodes for detecting EEG signals from corresponding areas of the head of the patient, in which the first unit and the second unit are configured to perform relative movements and thereby change their relative positions, the first unit and the second unit being shaped to fit a curved surface of the head of the patient; the first unit of the constituent block being movably connected to the second unit by means of a drive system provided between at least a part of the first unit and a part of the second unit, wherein the extracranial electrodes located on the first unit and on the second unit are configured to at least follow the relative movements between the first unit and the second unit in a first direction so as to move toward and/or away from an EEG measuring area on the head of the patient.

The present invention relates to an assembled, downward-pressing, multifunctional electroencephalogram (EEG) cap, at least comprising: a cap body, configured to be worn on a head of a patient, and formed by a plurality of constituent blocks, wherein each of the constituent blocks comprises a first unit and a second unit that carry extracranial electrodes for detecting EEG signals from corresponding areas of the head of the patient, in which the first unit and the second unit are configured to perform relative movements and thereby change their relative positions, the first unit and the second unit being shaped to fit a curved surface of the head of the patient; the first unit of the constituent block being movably connected to the second unit by means of a drive system provided between at least a part of the first unit and a part of the second unit, wherein the extracranial electrodes located on the first unit and on the second unit are configured to at least follow the relative movements between the first unit and the second unit in a first direction so as to move toward and/or away from an EEG measuring area on the head of the patient.

A system for performing fluid level measurements on a biological subject, the system including at least one substrate including a plurality of microstructures configured to breach a stratum corneum of the subject, at least some microstructures including an electrode, a signal generator operatively connected to at least one microstructure to apply an electrical stimulatory signal to the at least one microstructure and at least one sensor operatively connected to at least one microstructure, the at least one sensor being configured to measure electrical response signals from at least one microstructure. The system also includes one or more electronic processing devices that determine measured response signals, the response signals being at least partially indicative of a bioimpedance and perform an analysis at least in part using the measured response signals to determine at least one indicator at least partially indicative of fluid levels in the subject.

A system for performing fluid level measurements on a biological subject, the system including at least one substrate including a plurality of microstructures configured to breach a stratum corneum of the subject, at least some microstructures including an electrode, a signal generator operatively connected to at least one microstructure to apply an electrical stimulatory signal to the at least one microstructure and at least one sensor operatively connected to at least one microstructure, the at least one sensor being configured to measure electrical response signals from at least one microstructure. The system also includes one or more electronic processing devices that determine measured response signals, the response signals being at least partially indicative of a bioimpedance and perform an analysis at least in part using the measured response signals to determine at least one indicator at least partially indicative of fluid levels in the subject.

An electrode assembly (preferably in the form of a nerve cuff) comprises a base with first and second arms extending from opposite sides of the base, and which, in combination, define an arc. First and second electrically conductive electrodes extend along the inner surface of the first and second arms. Each electrode can comprise a single length of foil can or can comprise multiple discrete foil segments. The foils are electrically isolated from each other. Electrical wires, which are in electrical communication with the each of the foils, extend from the nerve cuff and are adapted to be electrically connected to a signal monitor. When the nerve cuff is applied to a nerve, the foils, in combination, substantially surround the nerve, with the first and second electrodes being on opposite sides of the nerve from each other. Also disclosed is a method of using the nerve cuff to monitor a nerve during a lumbar spinal surgery while the patient is anesthetized and paralyzed.

An electrode assembly (preferably in the form of a nerve cuff) comprises a base with first and second arms extending from opposite sides of the base, and which, in combination, define an arc. First and second electrically conductive electrodes extend along the inner surface of the first and second arms. Each electrode can comprise a single length of foil can or can comprise multiple discrete foil segments. The foils are electrically isolated from each other. Electrical wires, which are in electrical communication with the each of the foils, extend from the nerve cuff and are adapted to be electrically connected to a signal monitor. When the nerve cuff is applied to a nerve, the foils, in combination, substantially surround the nerve, with the first and second electrodes being on opposite sides of the nerve from each other. Also disclosed is a method of using the nerve cuff to monitor a nerve during a lumbar spinal surgery while the patient is anesthetized and paralyzed.

A perineal probe (10) having a probe body which includes electronic members (110, 111, 112) configured to interact with perineal muscles of the patient. The probe body has a cylindrical portion (12) configured to be positioned at the opening of the body cavity of a patient, and a flared portion (13) which extends from one end (121) of the cylindrical portion (12). The flared portion (13) extends widening from the cylindrical portion (12) as far as a free upper end (130), with the flared portion (13) being elastically deformable between a retracted position and a deployed position. The electronic members (110, 111, 112) are arranged on the flared portion (13) and/or on the cylindrical portion (12).

A perineal probe (10) having a probe body which includes electronic members (110, 111, 112) configured to interact with perineal muscles of the patient. The probe body has a cylindrical portion (12) configured to be positioned at the opening of the body cavity of a patient, and a flared portion (13) which extends from one end (121) of the cylindrical portion (12). The flared portion (13) extends widening from the cylindrical portion (12) as far as a free upper end (130), with the flared portion (13) being elastically deformable between a retracted position and a deployed position. The electronic members (110, 111, 112) are arranged on the flared portion (13) and/or on the cylindrical portion (12).

One aspect relates to a medical electrode, having a conductor, an insulation, which surrounds the conductor at least in some sections over its entire circumference, protrusions in the insulation, electrode segments arranged between the protrusions, and insulating areas arranged between the electrode segments, wherein the electrode segments have steps, wherein the steps engage with the insulating areas.