An electrode carrier system includes one or more electrode assemblies having an electrode body. One or more tubular members extend from the electrode body and define a lumen terminating in a distal opening. The electrode assemblies carry a reservoir containing a conductive fluid or gel. The reservoir is in fluid communication with the lumens in the tubular members, and the electrode assemblies are typically supported on a backing which may optionally be configured as a headband. Systems are for tracking patient movement may be used in combination with the electrode carrier system.

A sensor array includes a base for providing a probe signal and a plurality of modular recording sites. Each modular recording site of the plurality of modular recording sites is configured for receiving a signal and for converting the signal into a digital sensor signal using an in-situ analog-to-digital converter. Additionally, the sensor array includes a data compression unit configured for reducing a data rate of the digital sensor signal obtained by a modular recording site of the plurality of modular recording sites. The base is configured to provide the probe signal based on digital sensor signals provided by the plurality of modular recording sites.

A system for performing fluid level measurements on a biological subject, the system including at least one substrate including a plurality of microstructures configured to breach a stratum corneum of the subject, at least some microstructures including an electrode, a signal generator operatively connected to at least one microstructure to apply an electrical stimulatory signal to the at least one microstructure and at least one sensor operatively connected to at least one microstructure, the at least one sensor being configured to measure electrical response signals from at least one microstructure. The system also includes one or more electronic processing devices that determine measured response signals, the response signals being at least partially indicative of a bioimpedance and perform an analysis at least in part using the measured response signals to determine at least one indicator at least partially indicative of fluid levels in the subject.

A system for performing fluid level measurements on a biological subject, the system including at least one substrate including a plurality of microstructures configured to breach a stratum corneum of the subject, at least some microstructures including an electrode, a signal generator operatively connected to at least one microstructure to apply an electrical stimulatory signal to the at least one microstructure and at least one sensor operatively connected to at least one microstructure, the at least one sensor being configured to measure electrical response signals from at least one microstructure. The system also includes one or more electronic processing devices that determine measured response signals, the response signals being at least partially indicative of a bioimpedance and perform an analysis at least in part using the measured response signals to determine at least one indicator at least partially indicative of fluid levels in the subject.

An electrode carrier system includes one or more electrode assemblies having an electrode body. One or more tubular members extend from the electrode body and define a lumen terminating in a distal opening. The electrode assemblies carry a reservoir containing a conductive fluid or gel. The reservoir is in fluid communication with the lumens in the tubular members, and the electrode assemblies are typically supported on a backing which may optionally be configured as a headband. Systems are for tracking patient movement may be used in combination with the electrode carrier system.

Disclosed herein are embodiments of a conductive polymer doped with silica nanoparticles. In several embodiments, a coated electrode comprising a coating of the conductive polymer on a conductive surface of the electrode is provided. In some embodiments, the silica nanoparticles of the conductive polymer are mesoporous and are loaded with a pharmaceutical agent. Methods of using the conductive polymer doped with silica nanoparticles are also provided, including methods of recording or stimulating a bioelectric signal and methods of administering a pharmaceutical agent to a subject.

An electrode carrier system includes one or more electrode assemblies having an electrode body. One or more tubular members extend from the electrode body and define a lumen terminating in a distal opening. The electrode assemblies carry a reservoir containing a conductive fluid or gel. The reservoir is in fluid communication with the lumens in the tubular members, and the electrode assemblies are typically supported on a backing which may optionally be configured as a headband. Systems are for tracking patient movement may be used in combination with the electrode carrier system.

A high-density bioprobe array is provided comprising conductive or optical shanks. A method of making high-density bioprobe arrays also is provided. A bioprobe system using the array also is provided.

An electrode device for a living body includes: an electrode sheet including at least a pair of electrodes that receives a bioelectrical signal, a wiring member that transmits the bioelectrical signal received, a sensor module that outputs a signal relating to the bioelectrical signal to an exterior, a connector that connects the bioelectrical signal transmitted, to the sensor module, and a sheet member that supports the electrodes, the wiring member, the sensor module, and the connector; and an adhesive sheet that can be attached to a living body while covering the electrode sheet.

An electrode device for a living body includes: an electrode sheet including at least a pair of electrodes that receives a bioelectrical signal, a wiring member that transmits the bioelectrical signal received, a sensor module that outputs a signal relating to the bioelectrical signal to an exterior, a connector that connects the bioelectrical signal transmitted, to the sensor module, and a sheet member that supports the electrodes, the wiring member, the sensor module, and the connector; and an adhesive sheet that can be attached to a living body while covering the electrode sheet.