Described herein are embodiments of methods and apparatus for diagnosing neuromuscular diseases using an impedance-EMG needle, and for generating electrical impedance images using an impedance needle. Some embodiments provide an apparatus including an impedance-EMG needle, including both EMG electrodes and impedance electrodes, to measure both active and passive electrical properties of muscle. Other embodiments provide an apparatus including an impedance needle, including a plurality of impedance electrodes to measure impedance in tissue surrounding the impedance needle to generate an electrical impedance image. Use of such methods and apparatus may be advantageous in improving the accuracy of assessing and diagnosing neuromuscular disease.

Described herein are embodiments of methods and apparatus for diagnosing neuromuscular diseases using an impedance-EMG needle, and for generating electrical impedance images using an impedance needle. Some embodiments provide an apparatus including an impedance-EMG needle, including both EMG electrodes and impedance electrodes, to measure both active and passive electrical properties of muscle. Other embodiments provide an apparatus including an impedance needle, including a plurality of impedance electrodes to measure impedance in tissue surrounding the impedance needle to generate an electrical impedance image. Use of such methods and apparatus may be advantageous in improving the accuracy of assessing and diagnosing neuromuscular disease.

In various examples, a method of conductor management within a medical device includes providing a flexible substrate. The flexible substrate includes at least one routing feature. A hole is cut in the at least one routing feature with a cutting device. A conductor is passed through the hole in the at least one routing feature. The routing feature acts to maintain and manage positioning of the conductor within the medical device. The medical device, in some examples, includes a lead, with the conductor connected to an electrode of the lead after being routed through the routing feature.

In various examples, a method of conductor management within a medical device includes providing a flexible substrate. The flexible substrate includes at least one routing feature. A hole is cut in the at least one routing feature with a cutting device. A conductor is passed through the hole in the at least one routing feature. The routing feature acts to maintain and manage positioning of the conductor within the medical device. The medical device, in some examples, includes a lead, with the conductor connected to an electrode of the lead after being routed through the routing feature.

The present invention provides a device and methods of use related to the use of electrodes to continuously detect the presence and abundance of various biochemical compounds of interest with high spatial and temporal resolution, comprising the steps of inserting one or more electrodes in one or more locations selected from the group consisting of a tissue, an organ, a neural structure, a lymphatic vessel, a lymphatic node, an extravascular fluid compartment, and a peripheral blood vessel; applying a voltage scan to the electrode; an detecting a current indicative of the presence and abundance of the compound.

A system for monitoring a patient includes one or more processors and a sensor device implemented in circuitry. The system is configured to measure, using the sensor device, an impedance of tissue of the patient and determine, using one or more processors, a physiological parameter comprising at least one of a heart rate, cardiac output, vascular tone, perfusion level, fluid status, respiration effort, or respiration rate of the patient based on the impedance of the tissue of the patient. The system is configured to facilitate therapy, using the one or more processors, based on the determined physiological parameter.

An electrode carrier system includes one or more electrode assemblies having an electrode body. One or more tubular members extend from the electrode body and define a lumen terminating in a distal opening. The electrode assemblies carry a reservoir containing a conductive fluid or gel. The reservoir is in fluid communication with the lumens in the tubular members, and the electrode assemblies are typically supported on a backing which may optionally be configured as a headband. Systems are for tracking patient movement may be used in combination with the electrode carrier system.

A computer method for managing, processing and handling sensor signals from an in-ear monitor for immersive reality applications is provided. The method includes receiving, from a first electrode, a first electronic signal from a skin in a first ear canal of a user of an in-ear device, receiving, from a first microphone, a first acoustic signal from the first ear canal of the user of the in-ear monitor, and a second acoustic signal from a second ear canal of the user (binaural data capture), forming an acoustic waveform with the first acoustic signal, forming an electronic waveform with the first electronic signal, and identifying a health condition of the user based on the acoustic waveform and the electronic waveform. A device including a memory storing instructions and processors to execute the instructions to perform the above method are also provided.

A head stage designed for non-surgical placement of EEG electrodes in small animals is disclosed. The head stage is connected to thin barbed pin electrodes of multiple lengths, such that they can be placed into the brain at the chosen depth. A miniature device comprising a wireless transmitter or data logger can be attached using magnets or connectors to the stage. When the head stage is placed on the head of a small animal and pressure is applied on the stage, the set of pin electrodes penetrate the skull, such that the stage becomes firmly fixed to the skull. Further, the device includes electrodes on its body that eliminate the need of wires for EEG recordings. When the capsule including sharp electrodes is pressed toward the skull, the electrodes penetrate the bone and fixes the capsule onto the skull for recording biopotential signals from the brain.

A head stage designed for non-surgical placement of EEG electrodes in small animals is disclosed. The head stage is connected to thin barbed pin electrodes of multiple lengths, such that they can be placed into the brain at the chosen depth. A miniature device comprising a wireless transmitter or data logger can be attached using magnets or connectors to the stage. When the head stage is placed on the head of a small animal and pressure is applied on the stage, the set of pin electrodes penetrate the skull, such that the stage becomes firmly fixed to the skull. Further, the device includes electrodes on its body that eliminate the need of wires for EEG recordings. When the capsule including sharp electrodes is pressed toward the skull, the electrodes penetrate the bone and fixes the capsule onto the skull for recording biopotential signals from the brain.