Disclosed in various embodiments of the present invention are a method and a device comprising: a first electrode, a second electrode and a third electrode which make contact with the body of a user; an instrumentation amplifier for differentially amplifying signals received from the first electrode and the second electrode; a feedback amplifier for feeding back feedback noise to the body of the user through the third electrode; and a control circuit, wherein the control circuit is configured to analyze a noise level by using a biosignal obtained from the instrumentation amplifier, and control the gain of the feedback amplifier on the basis of the result of the analysis. Various embodiments are possible.

Disclosed in various embodiments of the present invention are a method and a device comprising: a first electrode, a second electrode and a third electrode which make contact with the body of a user; an instrumentation amplifier for differentially amplifying signals received from the first electrode and the second electrode; a feedback amplifier for feeding back feedback noise to the body of the user through the third electrode; and a control circuit, wherein the control circuit is configured to analyze a noise level by using a biosignal obtained from the instrumentation amplifier, and control the gain of the feedback amplifier on the basis of the result of the analysis. Various embodiments are possible.

The invention relates to a sensor for measuring a physiological parameter of a subject, comprising: a body (32) in an electrically insulating material, the body (32) comprising a base (31) and a plurality of protrusions (34) projecting from the base (31), and a plurality of capacitive elements (37) in an electrically conductive material, embedded inside the body (32), each capacitive element (37) being positioned inside the body (32), at an end of a respective protrusion (34), so that when the ends of the protrusions (34) are in contact with the skin of the subject, the capacitive elements are at a predefined distance from the skin.

Electrodes that can be formed in a flexible band of a wrist-worn device to detect hand gestures are disclosed. Multiple rows of electrodes can be configured to detect electromyography (EMG) signals produced by activity of muscles and tendons. The band can include removable electrical connections (e.g., pogo pins) to enable the electrode signals to be routed to processing circuitry in the housing of the wrist-worn device. Measurements between signals from the active electrodes and one or more reference electrodes can be obtained to capture EMG signals at a number of locations on the band. The measurement method and mode of operation (lower power coarse detection or higher power fine detection) can determine the location and number of electrodes to be measured. These EMG signals can be processed to identify hand movements and recognize gestures associated with those hand movements.

Electrodes that can be formed in a flexible band of a wrist-worn device to detect hand gestures are disclosed. Multiple rows of electrodes can be configured to detect electromyography (EMG) signals produced by activity of muscles and tendons. The band can include removable electrical connections (e.g., pogo pins) to enable the electrode signals to be routed to processing circuitry in the housing of the wrist-worn device. Measurements between signals from the active electrodes and one or more reference electrodes can be obtained to capture EMG signals at a number of locations on the band. The measurement method and mode of operation (lower power coarse detection or higher power fine detection) can determine the location and number of electrodes to be measured. These EMG signals can be processed to identify hand movements and recognize gestures associated with those hand movements.

A sensor for recording bioelectrical signals directly from hairy skin regardless of the amount or density of hair is fabricated using a polymer with an electrically conductive filler. The sensors have a stemmed conical microstructure array (CMSA) on the sensor surface that interfaces with and adheres to the skin between the hairs. The CMSA sensors are fabricated using a viscosity-controlled dip-pull process (VCDP), including dipping a mold into an electrically conductive polymer precursor having a selected viscosity that is optimized for formation of the conical microstructures upon a controlled pulling of the mold from the polymer precursor.

A sensor for recording bioelectrical signals directly from hairy skin regardless of the amount or density of hair is fabricated using a polymer with an electrically conductive filler. The sensors have a stemmed conical microstructure array (CMSA) on the sensor surface that interfaces with and adheres to the skin between the hairs. The CMSA sensors are fabricated using a viscosity-controlled dip-pull process (VCDP), including dipping a mold into an electrically conductive polymer precursor having a selected viscosity that is optimized for formation of the conical microstructures upon a controlled pulling of the mold from the polymer precursor.

The invention refers to a system for delivering a machine-learning based behavioral intervention for the care of withdraw symptoms such as Neonatal Abstinence Syndrome in neonates. The system obtains biosensor or behavioral information about a patient from a wearable device on the patient and makes a determinative recommendation or takes appropriate action based on its evaluation. The biosensor and behavioral information is collected by way of a wearable device over progressive periods of time. When the data is indicative of a need for treatment because the patient is exhibiting symptoms or indicating relapse traits, this information is sent to the system for evaluation. When the data is indicative of a need for treatment, action is taken in the form of a recommendation or when the device is configured to support direct treatment, direct action can be taken to modify alleviate the patient.

The invention refers to a system for delivering a machine-learning based behavioral intervention for the care of withdraw symptoms such as Neonatal Abstinence Syndrome in neonates. The system obtains biosensor or behavioral information about a patient from a wearable device on the patient and makes a determinative recommendation or takes appropriate action based on its evaluation. The biosensor and behavioral information is collected by way of a wearable device over progressive periods of time. When the data is indicative of a need for treatment because the patient is exhibiting symptoms or indicating relapse traits, this information is sent to the system for evaluation. When the data is indicative of a need for treatment, action is taken in the form of a recommendation or when the device is configured to support direct treatment, direct action can be taken to modify alleviate the patient.

Described herein is an implantable device having a sensor configured to detect an amount of an analyte, a pH, a temperature, strain, or a pressure; and an ultrasonic transducer with a length of about 5 mm or less in the longest dimension, configured to receive current modulated based on the analyte amount, the pH, the temperature, or the pressure detected by the sensor, and emit an ultrasonic backscatter based on the received current. The implantable device can be implanted in a subject, such as an animal or a plant. Also described herein are systems including one or more implantable devices and an interrogator comprising one or more ultrasonic transducers configured to transmit ultrasonic waves to the one or more implantable devices or receive ultrasonic backscatter from the one or more implantable devices. Also described are methods of detecting an amount of an analyte, a pH, a temperature, a strain, or a pressure.