A basket-type EP catheter is described. The EP catheter comprises a catheter proximal end that is electrically connected to a controller by an electrical cable having a single voltage-out (Vout) conductor and a catheter distal end supporting a distal connector that is detachably connectable to a basket-shaped configuration of a plurality of splines. Each spline supports an array of electrodes. By sampling the voltage signal on each of the plurality of electrodes sequentially or consecutively, only one Vout conductor is needed to transmit the voltage sample to the controller. In comparison to conventional EP catheters, this greatly reduces the number of conductors extending along the catheter shaft. The use of a Vout conductor is implemented by connecting a polling circuit or a one-shot circuit and a signal pass-transistor or transmission gate to each electrode.

A system is configured for receiving force data including at least one value indicating the amount of the force applied to the portion of the user and at least one value indicating a direction of the force applied to the portion of the user; obtaining mapping data specifying at least one relation between values of force applied to the portion of the user and changes in a functional responsiveness, functional and/or structural integrity, or both the functional responsiveness and the functional and/or structural integrity of the brain at one or more locations in the brain; estimating, based on the mapping data and the force data, an amount of force loading at one or more particular locations in the brain; and generating, based on the estimating, output data representing an amount of the damage to the brain at the one or more particular locations in the brain.

A system is configured for receiving force data including at least one value indicating the amount of the force applied to the portion of the user and at least one value indicating a direction of the force applied to the portion of the user; obtaining mapping data specifying at least one relation between values of force applied to the portion of the user and changes in a functional responsiveness, functional and/or structural integrity, or both the functional responsiveness and the functional and/or structural integrity of the brain at one or more locations in the brain; estimating, based on the mapping data and the force data, an amount of force loading at one or more particular locations in the brain; and generating, based on the estimating, output data representing an amount of the damage to the brain at the one or more particular locations in the brain.

A device for detecting electric potentials of the body of a patient has measuring electrode inputs (Y.sub.1, . . . , Y.sub.n) connected with and a plurality of outputs (A.sub.1, . . . , A.sub.n) via amplifiers (Op.sub.1, . . . , Op.sub.n). A summing unit (13) is connected with the outputs and outputs a mean value of the signals (E.sub.1, . . . , E.sub.n) output by the amplifiers. Common mode signals are removed from the signals (E.sub.1, . . . , E.sub.n) by a subtracting unit (19) which subtracts the output of the summing unit, amplified by an amplification factor (1/), from at least a portion of the output of the subtracting unit. The output of the subtracting unit is connected with the inputs of the amplifiers. The subtracting unit amplification factor (1/) and an amplification () of the amplifiers for the output of the subtracting unit are adapted, such that the reciprocal value of the amplification factor (1/) corresponds to the amplifiers amplification ().

An electrocardiograph (ECG) patch including: a first electrode; a second electrode; a high pass filter configured to receive a bias voltage and provide the bias voltage to the first electrode and the second electrode; and a signal processing unit configured to generate the bias voltage and provide the bias voltage to the high pass filter.

The present disclosure facilitates capture of biosignal such as biopotential signals in microvolts, or sub-microvolts, resolutions that are at, or significantly below, the noise-floor of conventional electrocardiographic and biosignal acquisition instruments. In some embodiments, the exemplified system disclosed herein facilitates the acquisition and recording of wide-band phase gradient signals (e.g., wide-band cardiac phase gradient signals, wide-band cerebral phase gradient signals) that are simultaneously sampled, in some embodiments, having a temporal skew less than about 1 s, and in other embodiments, having a temporal skew not more than about 10 femtoseconds. Notably, the exemplified system minimizes non-linear distortions (e.g., those that can be introduced via certain filters) in the acquired wide-band phase gradient signal so as to not affect the information therein.

A multi-device connector for ECG signals permits multiple medical devices to share patient-connected surface electrodes, providing a patient-side terminal set having a direct connection to one device-side terminal set and buffered connections to multiple additional device-side terminal sets. Invasive blood-pressure sensor readings may also be shared by providing a direct connection between a patient-side terminal set and multiple device-side terminal sets for blood-pressure signals and a direct connection between the patient-side terminal set and only one device-side terminal set. Indirect, scaled connections between the remaining device-side terminal sets and the patient-side terminal set may be provided.

Systems, apparatuses, and methods for electroporation ablation therapy are disclosed, with a protection device for protecting electronic circuitry, devices, and/or other components from induced currents and voltages generated during a cardiac ablation procedure. A system can include an ablation device near cardiac tissue of a heart. The system can further include a signal generator configured to generate a pulse waveform, where the signal generator coupled to the ablation device and configured to repeatedly deliver the pulse waveform to the ablation device in synchrony with a set of cardiac cycles of the heart. The system can further include a protection device configured to suppress induced current and voltage in an electronic device coupled to the protection device.

The present disclosure facilitates capture of biosignal such as biopotential signals in microvolts, or sub-microvolts, resolutions that are at, or significantly below, the noise-floor of conventional electrocardiographic and biosignal acquisition instruments. In some embodiments, the exemplified system disclosed herein facilitates the acquisition and recording of wide-band phase gradient signals (e.g., wide-band cardiac phase gradient signals, wide-band cerebral phase gradient signals) that are simultaneously sampled, in some embodiments, having a temporal skew less than about 1 s, and in other embodiments, having a temporal skew not more than about 10 femtoseconds. Notably, the exemplified system minimizes non-linear distortions (e.g., those that can be introduced via certain filters) in the acquired wide-band phase gradient signal so as to not affect the information therein.

A system for coma evaluation is provided, including: a stimulation-generating module operably affixed to a comatose patient for generating controllable stimulation signals to be applied to a target area on the comatose patient; a biosignal collecting module for acquiring a first EEG signal and a first EOG signal of the comatose patient in temporal association with the stimulation signals; and a processing module communicatively coupled to the biosignal collecting module, for separately processing the first EEG signal to obtain a stimulation EEG signal and a composite EOG signal; for processing the composite EOG, according to a second EOG signal measured without application of stimulation signals, to obtain an EOG signal relating to the induced eye-movement response of the comatose patient; and comprehensively processing the induced EOG signal and the stimulation EEG signal, so as to obtain a second EEG signal and evaluate coma severity of the comatose patient.