An implantable medical device (IMD) includes multiple stimulation engines (SEs) for independently stimulating respective electrode sets of a lead system. A voltage multiplier (VM) is configured to generate an adjustable target voltage at an output node. Each stimulation engine includes first switching circuitry to switchably connect an anodic node of the SE to the VM output node and second switching circuitry to switchably connect a cathodic node of the SE to a current sink circuit. Discharge switching circuitry may be disposed between the anodic and cathodic nodes of each SE. A selector and associated digital control logic block are operative to generate control signals for independently controlling respective SEs such that each SE may be activated to stimulate or discharge a corresponding select set of electrodes independently from or in concert with remaining SEs.

Disclosed herein are devices and methods of using a mobile or wearable device for the acquisition and spatial filtering of ECG signals from an electrode array. One variation of a mobile or wearable device comprises an array of electrodes, one or more reference electrodes, and a controller in communication with the electrodes. In one example, the one or more reference electrodes are located on a wrist-worn device (e.g., a watch), and the electrode array is located on an accessory device that may be contacted with a fingertip. One variation of a spatial filtering method comprises identifying the electrodes that have high levels of noise and excluding the ECG signals from those electrodes from further analyses. In another variation, a method of spatial filtering comprises identifying electrodes with low levels of noise and including only the ECG signals from those electrodes in further analyses.

Disclosed herein are devices and methods of using a mobile or wearable device for the acquisition and spatial filtering of ECG signals from an electrode array. One variation of a mobile or wearable device comprises an array of electrodes, one or more reference electrodes, and a controller in communication with the electrodes. In one example, the one or more reference electrodes are located on a wrist-worn device (e.g., a watch), and the electrode array is located on an accessory device that may be contacted with a fingertip. One variation of a spatial filtering method comprises identifying the electrodes that have high levels of noise and excluding the ECG signals from those electrodes from further analyses. In another variation, a method of spatial filtering comprises identifying electrodes with low levels of noise and including only the ECG signals from those electrodes in further analyses.

A wireless patient monitor comprises a generic activator module having a universal connection port that connects with any one of multiple sensor devices, a battery, and a radio transmitter wirelessly connected to a host device. The generic activator module connects to any one of multiple sensor devices via the universal connection port to provide power from the battery to the sensor device and to receive digital physiological data from the sensor device. The radio transmitter transmits the digital physiological data received from the sensor device to a host device.

A wireless patient monitor comprises a generic activator module having a universal connection port that connects with any one of multiple sensor devices, a battery, and a radio transmitter wirelessly connected to a host device. The generic activator module connects to any one of multiple sensor devices via the universal connection port to provide power from the battery to the sensor device and to receive digital physiological data from the sensor device. The radio transmitter transmits the digital physiological data received from the sensor device to a host device.

An apparatus includes a relay and sampling unit, a pacing unit, a pacing detection circuit, and a processor. The relay and sampling unit receives multiple electrocardiogram (ECG) signals that are sensed by respective electrodes in a heart of a patient, and digitize a first subset of the ECG signals, and forward a second subset of the ECG signals un-digitized over analog lines. The pacing unit outputs pacing signals, which the pacing detection circuit detects and outputs a trigger in response. The processor receives the trigger and identities of ones of the electrodes via which the pacing signals are to be applied, and, in response to identifying that the electrodes, via which the pacing signals are to be applied, are currently associated with the digitized ECG signals, instructs the relay and sampling unit to switch the identified electrodes to the analog lines for transferring the pacing signals.

An apparatus includes a relay and sampling unit, a pacing unit, a pacing detection circuit, and a processor. The relay and sampling unit receives multiple electrocardiogram (ECG) signals that are sensed by respective electrodes in a heart of a patient, and digitize a first subset of the ECG signals, and forward a second subset of the ECG signals un-digitized over analog lines. The pacing unit outputs pacing signals, which the pacing detection circuit detects and outputs a trigger in response. The processor receives the trigger and identities of ones of the electrodes via which the pacing signals are to be applied, and, in response to identifying that the electrodes, via which the pacing signals are to be applied, are currently associated with the digitized ECG signals, instructs the relay and sampling unit to switch the identified electrodes to the analog lines for transferring the pacing signals.

A system and method for measuring and monitoring charge states of one or more electrodes of an implanted stimulation lead system associated with an IPG. A Kelvin connection scheme operative with a switching circuit is provided for coupling select electrode terminals disposed in a Kelvin connection measurement loop in a switchable manner to sense and reference inputs of an analog-to-digital converter (ADC) configured as at least part of diagnostic circuitry for the IPG.

A method for wirelessly pairing a medical acquisition device and a host device. The method includes requesting an authentication key associated with the medical acquisition device to be entered into the host device, and producing a key pattern on the medical acquisition device representative of the authentication key, where the key pattern is non-numeric. The method further includes providing a plurality of targets on the host device, and receiving selections of the plurality of targets to form an entry pattern on the host device. The method further includes wirelessly pairing the medical acquisition device and the host device only when the entry pattern is determined to match the key pattern on the medical acquisition device.

A system and method for a multi-function remote ambulatory cardiac monitoring system. The system includes a housing and a microprocessor disposed within the housing. The microprocessor controls the remote ambulatory cardiac monitoring system. The system also includes an electrode for sensing ECG signals and the electrode being in communication with the microprocessor. An integrated cellular module also is included in the system, and the cellular module is connected to the microprocessor and disposed within the housing. The integrated cellular module transmits ECG signals to a remote center.