Medical catheterization is carried out by receiving a plurality of analog bioelectric signals in respective channels and multiplexing the bioelectric signals in respective selection events. The selection events comprise making a first connection with a reference voltage, thereafter breaking the first connection and making a second connection with one of the bioelectric signals. The method is further carried out by outputting the multiplexed bioelectric signals to an analog-to-digital converter.

Systems and methods are disclosed to determine an indication of a predicted response of a patient to at least one of cardiac resynchronization therapy (CRT) or multi-site pacing (MSP) therapy based on a patient metric determined using received physiologic information of the patient including at least one of heart sound information or respiration information from a first time period prior to the CRT or MSP therapy.

An analog front end system can include a filter bypass switch connected in a boot-strapped configuration to pull a control terminal of the filter bypass switch above or below a supply voltage. Using bootstrapped switches can allow both the charge injection and capacitive coupling of the bypass switches of a differential anti-alias filter (AAF) to be common mode. A differential input signal of the ADC is not affected by the charge injection and capacitive coupling of the bypass switches in the AAF filter to a first order.

A wireless patient monitor comprises a generic activator module having a universal connection port that connects with any one of multiple sensor devices, a battery, and a radio transmitter wirelessly connected to a host device. The generic activator module connects to any one of multiple sensor devices via the universal connection port to provide power from the battery to the sensor device and to receive digital physiological data from the sensor device. The radio transmitter transmits the digital physiological data received from the sensor device to a host device.

According to at least one example, an ambulatory medical device is provided. The device includes a plurality of electrodes disposed at spaced apart positions about a patient's body and a control unit. The control unit includes a sensor interface, a memory and a processor. The sensor interface is coupled to the plurality of electrodes and configured to receive a first ECG signal from a first pairing of the plurality of electrodes and to receive a second ECG signal from a second pairing of the plurality of electrodes. The memory stores information indicating a preferred pairing, the preferred pairing being either the first pairing or the second pairing. The processor is coupled to the sensor interface and the memory and is configured to resolve conflicts between interpretations of first ECG signal and the second ECG signal in favor of the preferred pairing.

A system for processing ECG recordings from multiple patients includes a preprocessing database containing unprocessed ECG records from multiple patients, a reporting database containing processed ECG records from multiple patients, a processor, and a triage module executable on the processor to assess each of the unprocessed ECG recordings from the multiple patients. The triage module is executable to detect a presence or absence of one or more known abnormalities and determines at least one abnormality identifier based on the detected known abnormality. One or more abnormality groups are then identified based on the abnormality identifiers. A normal group of ECG recordings from multiple patients is then identified from those ECG recordings that are not in the abnormality group. The normal group of ECG recordings is then stored in the reporting database then associated a normal identifier.

A wearable body composition measurement system includes: a sensor device including a first measurement circuitry configured to measure body composition; a second measurement circuitry configured to measure heart activity; and a strap arranged to attach the sensor device around a torso of a user; at least one processor coupled with the sensor device; and at least one memory storing a computer program code configured to cause the at least one processor to perform operations comprising: in a first measurement mode wherein the sensor device is attached around an abdominal area of the user, receiving body composition measurement data measured by the first measurement circuitry, computing a quantity of fat tissue in the abdominal area on the basis of the received body composition measurement data, and outputting the quantity of fat tissue via an interface; and in a second measurement mode wherein the sensor device is attached around a chest of the user, receiving heart activity measurement data from the second measurement circuitry, computing at least one heart activity parameter on the basis of the received heart activity measurement data, and outputting the at least one heart activity parameter via the interface.

A sensing unit includes a base, first electrodes, an insulating layer, second electrodes, and third electrodes. The first electrodes are arranged on the base, extend in a first direction, and are spaced apart from each other in a second direction different from the first direction. The first insulating layer is disposed on the first electrodes. The second electrodes are electrically insulated from the first electrodes by the insulating layer, extend in the second direction, and are spaced apart from each other in the first direction. The third electrodes are electrically insulated from the first electrodes by the insulating layer, extend in the second direction, and are electrically insulated from the second electrodes. The second electrodes and the third electrodes are alternately arranged in the first direction. The third electrodes may receive a driving signal or a sensing signal according to a sensing mode.

Detecting user contact with one or more electrodes of a physiological signal sensor can be used to ensure physiological signals measured by the physiological signal sensor meet waveform characteristics (e.g., of a clinically accurate physiological signal). In some examples, a mobile and/or wearable device can comprise sensing circuitry, stimulation circuitry, and processing circuitry. The stimulation circuit can drive one or more stimulation signals on one or more electrodes, the resulting signal(s) can be measured (e.g., by the sensing circuitry), and the processing circuitry can determine whether a user is in contact with the electrode(s). Additionally or alternatively, in some examples, mobile and/or wearable device can comprise saturation detection circuitry, and the processing circuitry can determine whether the sensing circuitry is saturated.

A coupled physiological signal measuring device is provided. The coupled physiological signal measuring device includes at least two measuring electrodes, a signal processing unit and a multiplex feedback circuit unit. The measuring electrodes are used to obtain a real-time physiological signal through measurement. The signal processing unit includes a discharge control element. If an electrostatic surge of the real-time physiological signal meets a condition, a discharge control signal is outputted. The multiplex feedback circuit unit is used to discharge the measuring electrodes according to the discharge control signal.