Methods and systems are disclosed for radiating a moving object. The method may comprise acquiring a plurality of indicators of the phase of a physiological cycle of a patient and a plurality of images of the patient that include a target. Each image may be taken at a different phase of the physiological cycle and may be registered to the phase at which the image was taken. The method may also include identifying the target in each of the plurality of images, calculating a dose of radiation required to treat the target, calculating the number, orientation, and dwell time of one or more radiation beams required to deliver the calculated required dose of radiation to the target, and calculating a position of each of the one or more radiation beams required to achieve the calculated orientation. Each position may be a function of the phase of the physiological cycle to which each of the plurality of images is registered.

An ultrasound cardiac stimulation system includes: a system for measuring the heart electrical activity; a system for generating a beam of focussed ultrasound signals focussed on a targeted zone, the signals being calibrated to generate electrical stimulation in a zone of the heart, the beam generation being synchronised with a first selected time of the electrocardiogram, the generation of the beam corresponding to a pulse with a duration of less than 80 ms; a system for locating the targeted zone coupled with a system for positioning the system for generating the focussed beam to control the beam of focussed ultrasound signals in the targeted zone, the location system being synchronised with the system for generating the beam of focussed signals; a single monitoring system following in real time a temperature and tissue deformation in the targeted zone, the monitoring system taking measurements in synchronisation with the rhythm of the electrocardiogram.

An ultrasound cardiac stimulation system includes: a system for measuring the heart electrical activity; a system for generating a beam of focussed ultrasound signals focussed on a targeted zone, the signals being calibrated to generate electrical stimulation in a zone of the heart, the beam generation being synchronised with a first selected time of the electrocardiogram, the generation of the beam corresponding to a pulse with a duration of less than 80 ms; a system for locating the targeted zone coupled with a system for positioning the system for generating the focussed beam to control the beam of focussed ultrasound signals in the targeted zone, the location system being synchronised with the system for generating the beam of focussed signals; a single monitoring system following in real time a temperature and tissue deformation in the targeted zone, the monitoring system taking measurements in synchronisation with the rhythm of the electrocardiogram.

Devices and methods for monitoring physiologic parameters are described where an airway device, in one embodiment, may comprise a mouthpiece section and an opening section defining one or more airway lumens therethrough with a first sensor in fluid communication with the one or more airway lumens and a second sensor positioned upon a hand-piece for contact against a portion of the user. The first sensor may be configured to detect an airway pressure when a user inhales or exhales through the one or more airway lumens, and the second sensor may be configured to detect a physiological signal from the user. Additionally, a controller may be in communication with the first and second sensors where the controller is programmed to correlate pressure oscillations in the airway pressure with heartbeats.

Methods of measuring biometric characteristics using a sensor positioned in an ear canal of a user are provided. The sensor is positioned on or connected to an ear tip, a contact hearing device, or one or more components thereof. One or more biometric signals may be sensed from the sensor. The biometric characteristic of the user is measured or derived from these sensed signals, and include but are not limited to the temperature of the user, acoustic signal(s) from the user, movement(s) of the user, a ballistocardiogram, an electrocardiogram, oxygen saturation, and blood pressure.

Methods of measuring biometric characteristics using a sensor positioned in an ear canal of a user are provided. The sensor is positioned on or connected to an ear tip, a contact hearing device, or one or more components thereof. One or more biometric signals may be sensed from the sensor. The biometric characteristic of the user is measured or derived from these sensed signals, and include but are not limited to the temperature of the user, acoustic signal(s) from the user, movement(s) of the user, a ballistocardiogram, an electrocardiogram, oxygen saturation, and blood pressure.

Methods and systems implement a pain assessment regularizing system to autonomously observe pained expressions and physiological measurements of a patient, in order to systematically collect data inputs which may be converted to pain assessment factors. The pain assessment regularizing system, by collecting this data, may combine it with clinical appraisals of pain intensity and patient self-reporting of pain intensity, weighing each factor appropriately in a manner sensitive to the progression of a patient care program, so as to lessen confounding effects of subjective pain assessment. The pain assessment regularizing system may generate a time series of regularized pain assessment factors, and further forecast a regularized pain assessment trend. A clinician may further operate the pain assessment regularizing system to review a visualization of both the time series and the forecast, providing the clinician with rigorously sampled and analytically predicted data which cannot be derived through manual and mental efforts.

Disclosed are a multiple physiological data collection device and system that collect, manually mark, sampling—physiological data for machine learning and AI analyses in a single operation background. Physiological data uploaded by sensing devices of different type and function, described in different formation, recorded at different times and/or pertaining to different person can be processed in one system. The invented system comprises a data uploading device, a data storage device and a data edition device and, optionally, an automated data analysis device.

Disclosed are a multiple physiological data collection device and system that collect, manually mark, sampling—physiological data for machine learning and AI analyses in a single operation background. Physiological data uploaded by sensing devices of different type and function, described in different formation, recorded at different times and/or pertaining to different person can be processed in one system. The invented system comprises a data uploading device, a data storage device and a data edition device and, optionally, an automated data analysis device.

An electrocardiogram electrode application system includes electrodes that detect electrical signals connected by a single connecting wire and transmitters capable of wirelessly transmitting the detected electrical signals to a computing device for analysis.