An initial set of parameters for operating one or more detection tools is automatically derived and subsequently adjusted so that each detection tool is more or less sensitive to signal characteristics in a region of interest. Detection tool(s) may be applied to physiological signals sensed from a patient (such as EEG signals) and may be configured to run in an implanted medical device that is programmable with the parameters to look for rhythmic activity, spiking, and power changes in the sensed signals, etc. A detection tool may be selected and parameter values derived in a logical sequence and/or in pairs based on a graphical representation of an activity type which may be selected by a user, for example, by clicking and dragging on the graphic via a GUI. Displayed simulations allow a user to assess what will be detected with a derived parameter set and then to adjust the sensitivity of the set or start over as desired.

An initial set of parameters for operating one or more detection tools is automatically derived and subsequently adjusted so that each detection tool is more or less sensitive to signal characteristics in a region of interest. Detection tool(s) may be applied to physiological signals sensed from a patient (such as EEG signals) and may be configured to run in an implanted medical device that is programmable with the parameters to look for rhythmic activity, spiking, and power changes in the sensed signals, etc. A detection tool may be selected and parameter values derived in a logical sequence and/or in pairs based on a graphical representation of an activity type which may be selected by a user, for example, by clicking and dragging on the graphic via a GUI. Displayed simulations allow a user to assess what will be detected with a derived parameter set and then to adjust the sensitivity of the set or start over as desired.

A neuromodulation system for treatment of physiological disorders. The system includes one or more stimulators for stimulating one or more cranial nerves; one or more detectors configured for detecting a predetermined physiological state; and a control unit that controls nerve stimulation by the one or more stimulators so that it is synchronized with the at least one predetermined physiological state detected by the one or more detectors. A method of neuromodulating a patient for treatment of physiological disorder. The method includes the steps of detecting a predetermined physiological state and applying stimulation to one of the cranial nerves during the predetermined physiological state by one or more stimulators of a neuromodulation system.

The present disclosure provides methods for the treatment of autism spectrum disorders. More particularly, the present disclosure relates to methods of using cord blood for the treatment of autism spectrum disorders.

The present disclosure provides methods for the treatment of autism spectrum disorders. More particularly, the present disclosure relates to methods of using cord blood for the treatment of autism spectrum disorders.

Various embodiments of a hearing device and a method of forming such device are disclosed. The device includes a housing adapted to be worn on or behind an ear of a wearer and includes a housing body and a top plate connected to the housing body. The hearing device further includes a sensor disposed on at least one of a first side surface and a second side surface of the housing body. The sensor is adapted to be in contact with either a pinna or a skull of the wearer. The sensor is further adapted to detect a physiological characteristic of the wearer and generate a sensor signal based on the physiological characteristic.

Various embodiments of a hearing device and a method of forming such device are disclosed. The device includes a housing adapted to be worn on or behind an ear of a wearer and includes a housing body and a top plate connected to the housing body. The hearing device further includes a sensor disposed on at least one of a first side surface and a second side surface of the housing body. The sensor is adapted to be in contact with either a pinna or a skull of the wearer. The sensor is further adapted to detect a physiological characteristic of the wearer and generate a sensor signal based on the physiological characteristic.

A method for generating sleep apnea information for a portion of body sensor data. The method of generating sleep apnea information is made dependent upon a determined presence or absence of arrhythmia within the portion of body sensor data. A first sleep apnea detection methodology is used in response to an absence of arrhythmia being detected within the portion of body sensor data.

A system includes a respiratory therapy system, a memory device, and a control system. The respiratory therapy system includes a respiratory therapy device supplying pressurized air, and a user interface coupled to the respiratory therapy device via a conduit to direct the pressurized air to an airway of a user. The memory device stores machine-readable instructions. The control system includes a processor(s) to execute the machine-readable instructions to: generate data, during a current sleep session, associated with a user of a respiratory therapy system; analyze the generated data to determine a value of a first metric that is associated with a sleep disordered breathing (SDB) condition; analyze the generated data to determine a value of a second metric that is associated with a health condition other than the SDB condition; and based at least in part on the determined value of the second metric, cause an action to be performed.

The present invention provides systems, methods, and articles for stress reduction and sleep promotion. A stress reduction and sleep promotion system includes at least one remote device, at least one body sensor, and at least one remote server. In other embodiments, the stress reduction and sleep promotion system includes machine learning.