The present invention relates a novel system and method to diagnose and predict systemic disorders including brain disorders and mental states in early stage and more accurately. More particularly, this invention relates to a novel method of EEG recording and processing through which multiple output data streams are taken together from a system like brain and the structure of their correlation matrix is studied through its eigenvector, eigendirection and eigenspaces and other signal processing techniques including compression sensing, wavelet transform, fast fourier transform etc.

For the purpose of improving sleep satisfaction for different human subjects individually, a sound source control device (20) includes: an acquirer (202) configured to acquire a biorhythm of a human subject; an estimator (204) configured to estimate sleep depths of the human subject from the acquired biorhythm of the human subject; a controller (230) configured to control a sound source (240) to play a sound in accordance with the acquired biorhythm of the human subject, the sound being defined using a prescribed parameter set; and an evaluator (220) configured to evaluate a sleep state of the human subject based on the estimated sleep depths of the human subject, and based on the evaluation, instruct the controller (230) to change at least a part of contents of the parameter set.

Methods, devices, systems, and non-transitory processor-readable storage media are disclosed for determining one or more biometric properties of a subject using multiple sensors positioned along a flexible backing. At least one processor of the multi-sensor device may be configured to receive output signals from the multiple sensors, identify at least one output signal from the received output signals that exhibit measurements of a targeted biological structure, determine the one or more biometric properties of the subject based on the identified at least one output signal received from at least one of the multiple sensors, and provide the determined one or more biometric properties.

An apparatus and a method is provided for detecting biometric signals of a driver and classifying the driver into a normal state or a fatigued state based on the biometric signals. An apparatus may include: a biometric signal measuring part configured to measure the biometric signals including a blood flow rate of a brain of the driver using an electro-encephalography (EEG), an electro-cardiography (ECG), and a functional near-infrared spectroscopy (fNIRS) of the driver; a biometric signal integral part configured to integrate the measured biometric signals, to extract characteristics of the respective biometric signals from the measured biometric signals and to then integrate the extracted characteristics, or to classify the extracted characteristics of the biometric signals and to then integrate the classified characteristics; and a driver state detecting part configured to detect the state of the driver based on the integrated biometric signals.

An active skull replacement system including an implant having an area A, an upper surface, and a bottom surface, adapted to be implanted at least in part into a skull of a subject so to substitute a portion of the skull, the bottom surface arranged to face at least in part a cranial cavity, and having a first wireless bidirectional data communication device, a device operably connected to the bottom surface of the implant, the device adapted to at least one of stimulate a physiological response and record a physiological parameter of the subject, and an external reader adapted to be placed on the scalp of the subject and including a second wireless bidirectional data communication device configured to communicate with the first wireless bidirectional data communication device of the implant to operate the device, wherein the external reader and the implant are fixed and aligned among each other through a magnetic device.

An electric apparatus of a bio-signal measurement system comprising a front part and a back part. The front part comprises a compartment at a back side of the front part, the compartment housing the back part when inserted therein. The back part comprises an electric circuit conductors and an extension plate, which extends to the front part within the electric apparatus. The extension plate comprises first electric contacts of the electric circuit conductors, the first electric contacts residing within the front part when the back part is within the compartment, the first electric contacts acting as counter-electrodes or electrodes of a front flap of a disposable patch electrode structure. The electric apparatus receives the front flap of the disposable patch electrode structure into a volume of the front part for forming a contact between the first electric contacts and the electrodes of the front flap. At least one of the back part and the front part comprises resin holes, and the compartment contains resin received through the resin holes, the resin immobilizing the front part and the back part with respect to each other and attaching them together.

An electric apparatus of a bio-signal measurement system comprising a front part and a back part. The front part comprises a compartment at a back side of the front part, the compartment housing the back part when inserted therein. The back part comprises an electric circuit conductors and an extension plate, which extends to the front part within the electric apparatus. The extension plate comprises first electric contacts of the electric circuit conductors, the first electric contacts residing within the front part when the back part is within the compartment, the first electric contacts acting as counter-electrodes or electrodes of a front flap of a disposable patch electrode structure. The electric apparatus receives the front flap of the disposable patch electrode structure into a volume of the front part for forming a contact between the first electric contacts and the electrodes of the front flap. At least one of the back part and the front part comprises resin holes, and the compartment contains resin received through the resin holes, the resin immobilizing the front part and the back part with respect to each other and attaching them together.

A method for transmitting compressed brainwave physiological signals is provided and including detecting a plurality of brainwave physiological signals of a subject, and generating an electroencephalography based on a time sequence of the plurality of brainwave physiological signals; splitting the electroencephalography into a plurality of sub-images based on the time sequence; using a plurality of static feature tags and a plurality of dynamic displacement tags stored in a brainwave database to identify at least one static feature tag and a plurality of associated dynamic displacement tags based on the time sequence according to the plurality of sub-images; generating at least one superimposed group tag, the superposed group tag is used to integrate the identified static feature tag and the associated dynamic displacement tag according to the time sequence; and transmitting the identified static feature tag, the associated dynamic displacement tag, and the superimposed group tag to a remote cloud system according to the time sequence.

A method for transmitting compressed brainwave physiological signals is provided and including detecting a plurality of brainwave physiological signals of a subject, and generating an electroencephalography based on a time sequence of the plurality of brainwave physiological signals; splitting the electroencephalography into a plurality of sub-images based on the time sequence; using a plurality of static feature tags and a plurality of dynamic displacement tags stored in a brainwave database to identify at least one static feature tag and a plurality of associated dynamic displacement tags based on the time sequence according to the plurality of sub-images; generating at least one superimposed group tag, the superposed group tag is used to integrate the identified static feature tag and the associated dynamic displacement tag according to the time sequence; and transmitting the identified static feature tag, the associated dynamic displacement tag, and the superimposed group tag to a remote cloud system according to the time sequence.

Method and devices are provided for treating subjects with Transcranial Magnetic Stimulation (TMS). According to some approaches, the methods and devices are configured for the treatment of ongoing seizures. Other approaches relate to the use of TMS as an antiepileptogenic or for use in determining preferential placement of intracranial probes.