A method, apparatus and computer program, the method comprising: receiving a first biopotential signal obtained by a first capacitive sensor; receiving a second biopotential signal obtained by a second capacitive sensor, the first capacitive sensor and the second capacitive sensor being positioned at different locations on a subject; synchronising biopotential signals obtained by the first capacitive sensor and the second capacitive sensor by applying a time adjustment to biopotential signals obtained by at least one of the first capacitive sensor or the second capacitive sensor; wherein features in at least one of the first biopotential signal and the second biopotential signal are used to synchronise the biopotential signals obtained by the first capacitive sensor and the second capacitive sensor.

The present disclose generally relates to systems and methods for active titration of one or more cranial or peripheral nerve stimulators to treat obstructive sleep apnea. The active titration can be accomplished in an automated fashion by a closed-loop process. The closed-loop process can be executed by a computing device that includes a non-transitory memory storing instructions and a processor to execute the instructions to perform operations. The operations can include defining initial parameters for the one or more cranial or peripheral nerve stimulators for a patient; receiving sensor data from sensors associated with the patient based on a stimulation with the one or more cranial or peripheral stimulators programmed according to the initial parameters; and adjusting the initial parameters based on the sensor data.

The present disclose generally relates to systems and methods for active titration of one or more cranial or peripheral nerve stimulators to treat obstructive sleep apnea. The active titration can be accomplished in an automated fashion by a closed-loop process. The closed-loop process can be executed by a computing device that includes a non-transitory memory storing instructions and a processor to execute the instructions to perform operations. The operations can include defining initial parameters for the one or more cranial or peripheral nerve stimulators for a patient; receiving sensor data from sensors associated with the patient based on a stimulation with the one or more cranial or peripheral stimulators programmed according to the initial parameters; and adjusting the initial parameters based on the sensor data.

A method is implemented by a computing device for helping a particular user use a user interface (UI). Electroencephalography (EEG) data is obtained that indicates brain activity of a particular user during a period in which that user views the UI and/or interprets help information that describes how to use the UI. Based on the EEG data, the computing device selects, from among multiple predefined cognitive states, the one or more cognitive states that characterize the particular user during the period. The computing device assists the particular user to use the UI by customizing the help information for the particular user based on the one or more selected cognitive states. A complementary computing device and computer program product are also disclosed.

A method is implemented by a computing device for helping a particular user use a user interface (UI). Electroencephalography (EEG) data is obtained that indicates brain activity of a particular user during a period in which that user views the UI and/or interprets help information that describes how to use the UI. Based on the EEG data, the computing device selects, from among multiple predefined cognitive states, the one or more cognitive states that characterize the particular user during the period. The computing device assists the particular user to use the UI by customizing the help information for the particular user based on the one or more selected cognitive states. A complementary computing device and computer program product are also disclosed.

A system and method provides closed-loop sedation, anesthesia, or analgesia by monitoring EEG and automatically adjusting the delivery of sedative, anesthetic, and/or analgesic drugs to maintain that desired level of cortical activity for transportation or evacuation of the injured, and for closed-loop anesthesia during surgical care, and at all echelons of care.

A system and method provides closed-loop sedation, anesthesia, or analgesia by monitoring EEG and automatically adjusting the delivery of sedative, anesthetic, and/or analgesic drugs to maintain that desired level of cortical activity for transportation or evacuation of the injured, and for closed-loop anesthesia during surgical care, and at all echelons of care.

Brain computer interface BCI comprising an input adapted to be connected to at least one electroencephalography EEG sensor to receive EEG signals, the BCI further comprising a processor running an associative model trained to simulate electrocorticography ECoG signal features from EEG signals received via the input, the BCI comprising an output to transmit the simulated ECoG signal features.

A computer-implemented method for voxelizing a 3D structural medical image of a human's brain. The method including obtaining a 3D structural medical image of the human's brain, including a reference frame, generating a voxelized 3D structural medical image, obtaining parameters of at least one EEG electrode sensor and, for each EEG electrode sensor: a localization in the voxelized 3D structural medical image's reference frame, and a sensor detection distance, obtaining a regular 3D grid of voxels, and for each voxel of the 3D grid, iteratively subdividing the voxel while the distance between the voxel and the localization of any electrode sensor is smaller than or equal to the sensor detection distance and while a size of the voxel is greater than a predetermined length, each subdivided voxel joining a finite number of voxels of the voxelized 3D structural medical image.

A computer-implemented method for voxelizing a 3D structural medical image of a human's brain. The method including obtaining a 3D structural medical image of the human's brain, including a reference frame, generating a voxelized 3D structural medical image, obtaining parameters of at least one EEG electrode sensor and, for each EEG electrode sensor: a localization in the voxelized 3D structural medical image's reference frame, and a sensor detection distance, obtaining a regular 3D grid of voxels, and for each voxel of the 3D grid, iteratively subdividing the voxel while the distance between the voxel and the localization of any electrode sensor is smaller than or equal to the sensor detection distance and while a size of the voxel is greater than a predetermined length, each subdivided voxel joining a finite number of voxels of the voxelized 3D structural medical image.