A system and method for improving a sleep disorder is provided. The system includes an oral appliance having a mandibular occlusal plate operably coupled to a maxillary occlusal plate, the plates molded to fit an individual's jaw; an actuator and one or more sensors in communication therewith for sensing physiologic parameters of a user, the actuator operably coupled to the maxillary occlusal plate for linearly advancing or retracting the mandibular occlusal plate based on commands received from a processing device.

A method of predicting substance levels from EEG data is disclosed. The method includes analyzing EEG data to obtain the average power for each of a plurality of predetermined frequency bands and calculating a value from the average powers derived for each frequency band, said value being calculated by combining the average powers for each frequency band by dividing and/or multiplying according to a predetermined order. The method further includes obtaining an estimate of the hormone level from the equation Y=bX+C, where Y is the substance level to be predicted, X is the value and b and C are constants, wherein the substance is selected from hormones, neuro transmitters and bio markers.

This invention is a mobile wearable electromagnetic brain activity monitor comprising a frame worn on a person's head, electromagnetic energy sensors which collect data concerning the person's electromagnetic brain activity, and a control unit. The electromagnetic energy sensors can be electroencephalogram (EEG) electrodes. In an example, the frame can be circular. In an example, the frame can loop around the person's head from one ear to the other ear. In an example, the frame can be an eyewear frame which also includes light-transmitting optical members.

A method and apparatus for locating tracts of electrical brain activity. A source localization procedure may be performed including solving the inverse problem subject to one or more constraints resulting from a tractographic procedure, and a tractographic procedure may be performed that includes obtaining a probabilistic assessment of tract connectivity that takes account of the results of a source localization procedure.

During a sEEG (stereo-electroencephalography) intervention into the skull of a patient, there is requirement to drill a large number of trajectories. Typically, instrument stabilisation platforms and robots for protocols requiring only one or two trajectories are rigidly fixed to the skull using surgical anchor members fixed into the skull around the one or two trajectories. However, because sEEG interventions require a large number of trajectories, an impractical number of surgical anchor members need to be fixed into the skull resulting in patient discomfort. Attachment of an intervention platform to all surgical anchor members is not required at once. Accordingly, it is proposed to search for intersection points of the maximum extent of an intervention platform between at least two trajectory entry points on an object of interest of patient, so that at least one surgical anchor member can be shared when the intersection point is at first and the second trajectories. Any reduction in the number of surgical anchor members inserted into a patient reduces risk and discomfort. The positioning of the shared anchor members can be optimised to enable good mechanical stability, and/or optical registration performance. Furthermore, the number of surgical anchor members required for intervention can be reduced. Because the surgical anchor members are sterilised and made from high quality metal, a cost for performing the procedure can also be reduced.

Systems and methods are disclosed for monitoring a patient by positioning the patient for a predetermined medical mission; sensing biometric and physical conditions of a patient during the mission, and displaying a multimedia interaction with the patient to keep the patient in a predetermined position to improve efficacy of a medical mission.

A biological signal acquirer is attached to a subject and acquires a biological signal of the subject. A transmitter carried by the subject transmits the biological signal. A first communication port and a first camera are installed in a first location and connectable to a network. A second communication port and a second camera are installed in a second location and connectable to the network. A biological information acquiring device is connectable to the network and provided with a switcher. The switcher acquires, when communication establishment between the transmitter and the first communication port is detected, the biological signal through the first communication port as well as a first image taken by the first camera, and acquires, when communication establishment between the transmitter and the second communication port is detected, the biological signal through the second communication port as well as a second image taken by the second camera.

A system and a method for generating stress level information for an individual and stress level resilience information for an individual, which includes a stress information processing module configured to process stress information for the individual, the stress information for the individual comprising at least two of psychometric information for the individual, physiological information for the individual, behavioural information for the individual, and cognitive function information for the individual.

Provided is a sleep guidance device that serves to control a stimulus imparter for imparting stimuli to a human subject. The sleep guidance device acquires a biorhythm of the human subject; estimates sleep depths of the human subject from the acquired biorhythm of the human subject; and controls the stimulus imparter to impart a stimulus to the human subject in accordance with the acquired biorhythm of the human subject, and from among the sleep depths, a current sleep depth estimated for the human subject.

Apparatuses (including devices, kits, and systems) and methods to non-invasively and chemically (rather than thermally) activate thermoreceptors to modulate sleep. For example, described herein are apparatuses including topical compositions that stimulate thermoreceptors on the subject's skin (e.g., forehead, hands, and/or feet) for a period of time to induce a sensation of temperature (heat or cold) without significantly altering the person's actual skin temperature to improve sleep quality, including reducing sleep-onset latency, enhancing depth of sleep, and/or extending the amount of time a subject sleeps. The subject may be suffering from insomnia or some other sleep disorder.