A system comprises an ultrasound subsystem and a magnetic resonance imaging (MRI) subsystem. The ultrasound subsystem applies pulses of focused ultrasound having one or more parameters to an identified location in a subject that is to receive treatment. The parameters are determined in accordance with a magnetic resonance guided focused ultrasound (MRgFUS) treatment plan. The MRI subsystem acquires functional image data corresponding to the identified location concurrently with the applied pulses of focused ultrasound. The MRI subsystem obtains a reconstructed series of functional images of the subject using the functional image data. The functional images are indicative of a first region within the identified location in which neuronal activity has been modified by the applied pulses. The system is configured to adjust one or more parameters of the MRgFUS treatment plan using the reconstructed series of functional images.

A system comprises an ultrasound subsystem and a magnetic resonance imaging (MRI) subsystem. The ultrasound subsystem applies pulses of focused ultrasound having one or more parameters to an identified location in a subject that is to receive treatment. The parameters are determined in accordance with a magnetic resonance guided focused ultrasound (MRgFUS) treatment plan. The MRI subsystem acquires functional image data corresponding to the identified location concurrently with the applied pulses of focused ultrasound. The MRI subsystem obtains a reconstructed series of functional images of the subject using the functional image data. The functional images are indicative of a first region within the identified location in which neuronal activity has been modified by the applied pulses. The system is configured to adjust one or more parameters of the MRgFUS treatment plan using the reconstructed series of functional images.

The present invention relates to an electrode comprising a conductive pressure sensitive adhesive layer and a conductive layer. Furthermore, the invention refers to a method of manufacturing the electrode and to the use of the electrode for monitoring biosignals.

Disclosed are a method and a device for providing a mental massage to help treat anxiety and depression. According to one embodiment of the present disclosure, a massage device for providing a mental massage to help treat anxiety and depression is disclosed, the device including: a mental state determination unit for determining a mental state on the basis of a biosignal of a user; a mental massage pattern determination unit for determining a mental massage pattern on the basis of the determined mental state; and a mental massage provision unit for providing a massage on the basis of the mental massage pattern.

The invention relates to a method for the real-time monitoring and evaluation of the state of a patient with a neurological condition from the indicative parameters of the state of the patient obtained by means of an EEG, comprising a step of measuring the EEG by means of at least one sensor, a step of processing the measured values, a step of extracting at least one set of values of the indicative parameters of the state of the patient, each set of values being extracted from time segments of the EEG, a step of calculating for each time segment the risk level of the patient suffering a crisis due to the neurological condition, the risk level being calculated by applying at least one mathematical classification model to each corresponding set of values, and a step of classifying the state of the patient between at least an alert or preictal state and a non-alert or non-preictal state, depending on a threshold level.

The invention relates to a method for the real-time monitoring and evaluation of the state of a patient with a neurological condition from the indicative parameters of the state of the patient obtained by means of an EEG, comprising a step of measuring the EEG by means of at least one sensor, a step of processing the measured values, a step of extracting at least one set of values of the indicative parameters of the state of the patient, each set of values being extracted from time segments of the EEG, a step of calculating for each time segment the risk level of the patient suffering a crisis due to the neurological condition, the risk level being calculated by applying at least one mathematical classification model to each corresponding set of values, and a step of classifying the state of the patient between at least an alert or preictal state and a non-alert or non-preictal state, depending on a threshold level.

This disclosure is related to methods of objectively detecting and measuring neuropathic pain in a subject.

The present disclosure relates to a pair of intelligent glasses and a glasses box. The intelligent glasses can include a frame assembly having an inner frame portion and an outer frame portion that is arranged around the inner frame portion, a detection component configured to detect physiological characteristics of a wearer, a control component connected with the detection component and configured to acquire a control signal generated according to the physiological characteristics and a treatment component, connected with the control component and configured to output treatment signals according to the control signal. One or more accommodating spaces are formed between the inner frame portion and the outer frame portion. The treatment signals include at least one of a phototherapy signal, a sonic wave signal, a sound wave signal, magnetic waves, or electromagnetic waves. The detection component, the control component and the treatment component are located in the accommodating spaces.

The present invention provides systems and methods for management and orchestration of a fleet of remote Internet-of-Things (IoT) devices. The present invention includes a platform for onboarding, provisioning, and managing remote IoT devices throughout their lifetime. The platform includes portals for manufacturers, vendors, and consumers to access device data and sensor data collected by the devices. The data collected by the portal is used to control the fleet of remote IoT devices as well as make recommendations, e.g., for sleep promotion and stress reduction.

A system monitors fatigue of a user. The system (100) may include one or more data sources, such as a non-obtrusive sleep sensor, configured to generate objective sleep measures of the user. The system may also include a fatigue monitoring module, which may be configured to generate an assessment, such as in one or more processors, of the fatigue state of the user based on the data from the one or more data sources.