A61B5/388

Systems and methods for preventing noise in an electric waveform for neural stimulation, block, or sensing
11376436 · 2022-07-05 · ·

One aspect of the present disclosure relates to a system that can prevent unintended signal components (noise) in an electric waveform that can be used for at least one of neural stimulation, block, and/or sensing. The system can include a signal generator to generate a waveform that includes an intended electric waveform and unintended noise. The system can also include a signal transformer device (e.g., a very long wire) comprising a first coil and a second coil. The first coil can be coupled to the signal generator to receive the waveform and remove the unintended noise from the electric waveform. The second coil can pass the electric waveform to an electrode. The second coil can be coupled to a capacitor that can prevent the waveform from developing noise at an electrode/electrolyte interface between an electrode and a nerve.

Methods of recording responses of and stimulating bioelectric tissue

Aspects of the disclosure relate to methods of conducting an intraoperative procedure including providing an electrode assembly having a pledget substrate having a surface that is hydrophilic, at least one electrode supported by and positioned within the pledget substrate, and a lead wire assembly interconnected to the at least one electrode. Methods can further include creating an incision to access bioelectric tissue of a patient and applying the pledget substrate to the tissue, such as a nerve, for example. The pledget substrate conforms and fixates to the tissue to secure the electrode assembly in position. The electrode is then activated to record bioelectric responses of or stimulate the tissue. In some embodiments, the pledget substrate includes two bodies, each including at least one electrode, the two bodies being selectively separable so that the bodies can be repositioned with respect to one another.

METHOD AND DEVICE FOR GENERATING HEART MODEL REFLECTING ACTION POTENTIAL DURATION RESTITUTION
20220211330 · 2022-07-07 ·

A method for generating a heart model reflecting action potential duration restitution is provided, which can visually output the maximum slope of the correlation between a relaxation period and an action potential duration at every point included in a three-dimensional heart model.

HYBRID CONTROL POLICY FOR ECAP-SERVOED NEUROMODULATION
20220218996 · 2022-07-14 ·

Systems, devices, and techniques for adjusting electrical stimulation are described. For example, processing circuitry is configured to receive, via a sensing electrode located at a target region of a patient, a plurality of evoked compound action potential (ECAP) signals elicited from respective electrical stimuli delivered to the patient; determine, based on the plurality of ECAP signals, an aggressor category for at least some ECAP signals of the plurality of ECAP signals, the aggressor category determined from a plurality of aggressor categories; determine, based on the aggressor category, a set of control policy parameters that at least partially define closed-loop control of stimulation therapy; and controlling delivery of the stimulation therapy according to at least the set of control policy parameters and one or more subsequent ECAP signals.

NEUROMONITORING DEVICE

The present disclosure relates to a neuromonitoring device. The neuromonitoring device may include a probe, an operation part, and a display part. The probe may include a probe head, an elastic piece, and an elastic measuring piece. The probe head may be connected to the elastic piece. The elastic measuring piece may be connected to the elastic piece and may be used to measure an elasticity value of the elastic piece and convert the elasticity value into a first electrical signal. The display part may be configured to display prompt information. The prompt information may include prompt information regarding the elasticity value determined based on the first electrical signal.

NEUROMONITORING DEVICE

The present disclosure relates to a neuromonitoring device. The neuromonitoring device may include a probe, an operation part, and a display part. The probe may include a probe head, an elastic piece, and an elastic measuring piece. The probe head may be connected to the elastic piece. The elastic measuring piece may be connected to the elastic piece and may be used to measure an elasticity value of the elastic piece and convert the elasticity value into a first electrical signal. The display part may be configured to display prompt information. The prompt information may include prompt information regarding the elasticity value determined based on the first electrical signal.

Biometric information display device, biometric information display method, and computer-readable recording medium, extracting current components at positions along a neural pathway based on current information reconstructed based on magnetic field measurement data generated by subject

A biometric information display device includes a display controller configured to display a morphological image indicative of a morphology of a subject, on a display, an input controller configured to receive a designation of a specified position on the morphological image, a pathway generating section configured to generate a pathway based on the specified position on the morphological image, and a current extracting section configured to extract current components at a plurality of positions along the pathway, based on current information reconstructed based on magnetic field measurement data generated by the subject. The display controller displays the current components extracted along the pathway on the display.

STIMULATION SYSTEM

A method for detecting and identifying a patient physiological response includes stimulating, via a stimulating electrode coupled to a patient, one or more nerves of the patient. The method includes recording, via a recording electrode coupled to the patient, a plurality of resultant electrical waveforms. The method includes determining, based on the plurality of resultant electrical waveforms, whether at least a subset of the plurality of resultant electrical waveforms includes a patient physiological response. The determining includes comparing the subset of resultant electrical waveforms of the plurality of resultant electrical waveforms to a model waveform from a database of a plurality of model waveforms. The determining includes determining, based on the comparison, a comparison feature. The comparison feature indicates whether the patient physiological response exists in the subset. The method includes displaying, via a display, an indication that the patient physiological response exists in the subset of resultant electrical waveforms.

STIMULATION SYSTEM

A method for detecting and identifying a patient physiological response includes stimulating, via a stimulating electrode coupled to a patient, one or more nerves of the patient. The method includes recording, via a recording electrode coupled to the patient, a plurality of resultant electrical waveforms. The method includes determining, based on the plurality of resultant electrical waveforms, whether at least a subset of the plurality of resultant electrical waveforms includes a patient physiological response. The determining includes comparing the subset of resultant electrical waveforms of the plurality of resultant electrical waveforms to a model waveform from a database of a plurality of model waveforms. The determining includes determining, based on the comparison, a comparison feature. The comparison feature indicates whether the patient physiological response exists in the subset. The method includes displaying, via a display, an indication that the patient physiological response exists in the subset of resultant electrical waveforms.

Systems and methods for treating cancer and/or augmenting organ function
11272877 · 2022-03-15 · ·

Systems, methods and devices for controlled sympathectomy procedures for neuromodulation in the treatment of subjects having neoplastic conditions are disclosed. Systems, methods, and devices for interventionally treating a cancerous tumor and cancer related pain are disclosed.