The present invention relates to a system and methods generally aimed at monitoring the angular orientation between two locations within a fluoroscopic image and especially for monitoring the angular orientation between two locations within a fluoroscopic image and a predetermined target angle.

The present disclosure relates to the field of denervation. Specifically, the present disclosure relates to systems and methods for preventing an electrical signal from travelling along a target nerve. In particular, the present disclosure relates to systems and methods for relieving a pulmonary symptom by denervating the internal branch of the superior laryngeal nerve.

The present disclosure relates to the field of neuromodulation. Specifically, the present disclosure relates to systems and methods for reversibly blocking an electrical signal from travelling along a target nerve. In particular, the present disclosure relates to systems and methods for relieving a pulmonary symptom by reversibly blocking an electrical signal from travelling along the vagus nerve or internal branch of the superior laryngeal nerve

The application relates to a hearing assistance system (a method and its use) for processing an input signal representative of sound according to a user's needs, the hearing assistance system comprising an implanted part adapted for being at least partially implanted in a user's head and comprising a sensing unit capable of measuring an endocochlear potential at one or more positions along the length of the cochlear partition. The hearing assistance system further comprises a decoder configured to receive said endocochlear potentials or signals derived therefrom and to transform the received signals into signals appropriately conditioned for use as control inputs to the signal processing unit, and wherein the signal processing unit is configured to process the electric input signal in dependence of said control inputs from said decoder. Thereby the processing of the audio signal of a hearing assistance device can be automatically adapted over time.

Methods are disclosed for treating a subject having a disease or disorder comprising providing the subject with an acoustic energy stimulus derived from a disease-specific, condition-specific, endogenous mediator-specific or pharmacologic agent-specific neurogram in an amount and manner effective to treat the disease or disorder.

Presented herein are objective techniques for determining the upper limit of the dynamic range (i.e., the comfort level) of implanted stimulating contacts through the use of electrocochleography (ECoG) measurements to indirectly detect the onset and duration of a recipient's stapedius reflex. In particular, stimulation is delivered to a recipient's cochlea to trigger the onset of the stapedius reflex and the resulting acoustic impedance change is detected by monitoring the acoustically evoked ECoG.

Systems, devices, and methods for using vagus nerve stimulation to treat demyelination disorders and/or disorder of the blood brain barrier are described. The vagus nerve stimulation therapy described herein is configured to reduce or prevent demyelination and/or promote remyelination to treat various disorders related to demyelination, such as multiple sclerosis. A low duty cycle stimulation protocol with a relatively short on-time and a relatively long off-time can be used.

Systems, devices, and methods for using vagus nerve stimulation to treat demyelination disorders and/or disorder of the blood brain barrier are described. The vagus nerve stimulation therapy described herein is configured to reduce or prevent demyelination and/or promote remyelination to treat various disorders related to demyelination, such as multiple sclerosis. A low duty cycle stimulation protocol with a relatively short on-time and a relatively long off-time can be used.

An intravascular catheter for peri-vascular and/or peri-urethral tissue ablation includes multiple needles advanced through supported guide tubes which expand around a central axis to engage the interior surface of the wall of the renal artery or other vessel of a human body allowing the injection an ablative fluid for ablating tissue, and/or nerve fibers in the outer layer or deep to the outer layer of the vessel, or in prostatic tissue. The system may also include a means to limit and/or adjust the depth of penetration of the ablative fluid into and beyond the tissue of the vessel wall. The catheter may also include structures which provide radial and/or lateral support to the guide tubes so that the guide tubes expand uniformly and maintain their position against the interior surface of the vessel wall as the sharpened injection needles are advanced to penetrate into the vessel wall. A method can involve injection/infusion of the ablative fluid over an extended time period of at least 10 seconds or with two injections at two different penetration depths to reduce or eliminate patient pain during ablation.

An intravascular catheter for peri-vascular and/or peri-urethral tissue ablation includes multiple needles advanced through supported guide tubes which expand around a central axis to engage the interior surface of the wall of the renal artery or other vessel of a human body allowing the injection an ablative fluid for ablating tissue, and/or nerve fibers in the outer layer or deep to the outer layer of the vessel, or in prostatic tissue. The system may also include a means to limit and/or adjust the depth of penetration of the ablative fluid into and beyond the tissue of the vessel wall. The catheter may also include structures which provide radial and/or lateral support to the guide tubes so that the guide tubes expand uniformly and maintain their position against the interior surface of the vessel wall as the sharpened injection needles are advanced to penetrate into the vessel wall. A method can involve injection/infusion of the ablative fluid over an extended time period of at least 10 seconds or with two injections at two different penetration depths to reduce or eliminate patient pain during ablation.