A personal monitoring device has a sensor assembly configured to sense physiological signals upon contact with a user's skin. The sensor assembly produces electrical signals representing the sensed physiological signals. A converter assembly, integrated with, and electrically connected to the sensor assembly, converts the electrical signals generated by the sensor assembly to a frequency modulated physiological audio signal having a carrier frequency in the range of from about 6 kHz to about 20 kHz.

This disclosure describes, among other embodiments, systems and related methods for selecting electrode combinations to be used during nerve pacing procedures. A first set of electrode combinations of a nerve pacing system, such as a phrenic nerve pacing system for diaphragm activation, may be mapped (or tested) to determine the location of the electrode combinations relative to a target nerve. Once the general location of the target nerve is known, a more localized second set of electrode combinations may be tested to determine the most suitable electrode combinations for nerve stimulation. At various stages of the mapping process, electrode combinations that are non-optimal may be discarded as candidates for use in a nerve pacing procedure. The systems and methods described herein may allow for the selection of electrode combinations that are most suitable for stimulation of the left and right phrenic nerves during diaphragm pacing.

The disclose describes a stationary dilator with one or more electrodes in the distal region that are rotatable around the longitudinal axis of the dilator. The one or more electrodes are operable to deliver electrical stimulation signals to tissue through which the dilator is passed. The stimulation signals can be used for determining nerve directionality and optionally nerve proximity during surgical procedures involving the presence of neural structures.

The disclose describes a stationary dilator with one or more electrodes in the distal region that are rotatable around the longitudinal axis of the dilator. The one or more electrodes are operable to deliver electrical stimulation signals to tissue through which the dilator is passed. The stimulation signals can be used for determining nerve directionality and optionally nerve proximity during surgical procedures involving the presence of neural structures.

Detection of placement of dental aligners in patient mouth on teeth for indication of wearing compliance. Described herein are apparatuses and methods for detecting wearing, including compliance. In some variations these apparatuses and methods may include a sensor configured to detect deflection of the one or more deflectable structures. In some variations, these apparatuses and methods may include a proximity sensor coupled to the appliance shell and configured to generate sensor data when in proximity with intraoral tissue.

Detection of placement of dental aligners in patient mouth on teeth for indication of wearing compliance. Described herein are apparatuses and methods for detecting wearing, including compliance. In some variations these apparatuses and methods may include a sensor configured to detect deflection of the one or more deflectable structures. In some variations, these apparatuses and methods may include a proximity sensor coupled to the appliance shell and configured to generate sensor data when in proximity with intraoral tissue.

A device for performing blood flow restriction training during the day, integrated with a garment, and controllable to apply a desired compression level to a range of muscles with the intent on improving the health and fitness of a user doing normal daily activities.

A display device and a method of manufacturing the same are disclosed. In one aspect, the display device includes a substrate including a separation area and a plurality of pixel formed over the substrate. The separation area is formed between adjacent pixels, and a plurality of through holes are respectively defined by a plurality of surrounding inner surfaces of the separation area, and wherein each of the inner surfaces passes through the substrate. The display device also includes an encapsulation layer formed over the substrate and covering the inner surfaces of the separation area.

The circuit for measuring a bio-stimulating and bio-signal according to an embodiment of the inventive concept may include a bio-stimulating signal generating circuit, a bio-signal electrode, a switch block, first and second resistors, and a bio-signal measuring circuit. The bio-stimulating signal generating circuit may generate a bio-stimulating signal in a bio-stimulating mode. The bio-signal electrode may to deliver the bio-stimulating signal generated in the bio-stimulating mode and receive a bio-signal in a bio-signal measuring mode. The switch block may be turned on in a case where a voltage of the bio-stimulating signal is greater than a first reference voltage or lower than a second reference voltage. The first and second resistors may be serially connected between the bio-signal electrode and the switch block and divide a voltage of a signal of the bio-signal electrode according to whether the switch block is turned on. The bio-signal measuring circuit may measure voltage signals divided by the first and second resistors or measure a signal of the bio-signal electrode, according to whether the switch block is turned on. The first reference voltage may be greater than the second reference voltage.

The present invention relates to systems and methods for planning and/or providing neurostimulation for a patient. An example system includes a pathological spinal cord map storage module for storing at least one pathological spinal cord map describing activation of a spinal cord of a patient, a healthy spinal cord map storage module for storing at least one reference map describing physiological activation of the spinal cord of at least one healthy subject, an analysis module for generating a deviation map, the deviation map describing an activation difference between the pathological spinal cord map and the reference map, and a compensation module for calculating, based on the deviation map, a neurostimulation protocol for compensating the activation difference.