The present invention relates to methods for modulating bursts of oscillatory brain activity, such as sleep spindles, in a subject. The invention further relates to methods of improving memory or cognitive function in a subject and method of modulating or enhancing the frequency of occurrence, structure, amplitude, and/or synchronization of sleep spindles in a subject by detecting a burst of oscillatory brain activity in the subject and passing an oscillating current through the skull of the subject.

A computer-implemented method can include determining an amplitude for each of a plurality of input channels, corresponding to respective nodes. A measure of similarity can be computed between the input channel of each node and the input channel of its neighboring nodes. The method can also include comparing an amplitude for each node relative to other nodes to determine temporary bad channels. For each of the temporary bad channels, a measure of similarity can be computed between the input channel of each node and the input channel of its neighboring nodes. Channel integrity can then be identified based on the computed measures of similarity.

A wearable safety device assembly is disclosed. The assembly includes at least one sensor configured to obtain one or more signals from a user. One of the at least one sensors comprises a vestibular (and startling/surprise related) motion sensor specially configured to obtain vestibular (and startling/surprise related) signals. Vestibular (and startling/surprise related) data indicative of a user's vestibular (and startling/surprise related) state is extracted from the one or more signals and used to determine whether a user is undergoing an event such as a fall or a startling movement. When it is determined that a user is undergoing an event, the processor of the wearable safety device transmits an activation signal to the safety device. Optionally, the processor may transmit data and information related to the vestibular (and startling/surprise related) system and recorded signals to a data repository.

Systems and methods of the present disclosure are directed to systems and methods for treating cognitive dysfunction in a subject in need thereof. The system can include a neural stimulation system that receives an indication of an ambient audio signal detected by a microphone. The system selects, from a profile, an audio signal including a fixed parameter and a variable parameter. The system sets the variable parameter to a first value. The system generates an output signal based on the fixed parameter and the first value, and provides the output signal to the speaker. The system measures a physiological condition of the subject, adjusts the variable parameter to a second value, generates a second output signal based on the fixed parameter and the second value of the variable parameter, and provides the output signal to the speaker to cause the speaker to provide modified sound to the subject.

Systems and methods of the present disclosure are directed to systems and methods for treating cognitive dysfunction in a subject in need thereof. The system can include eyeglasses, a photodiode positioned to detect ambient light, light sources, and an input device. The system can include a neural stimulation system that retrieves a profile and selects a light pattern having a fixed parameter and a variable parameter. The neural stimulation system can set a value of the variable parameter of the light pattern, construct an output signal, and then provide the output signal to the light sources to direct light towards the fovea.

Systems and methods of the present disclosure are directed to systems and methods for treating cognitive dysfunction in a subject in need thereof. The system can include a light source and a speaker. A visual neural stimulation system provides, via the light source, visual stimulation having a first value of a first parameter. An auditory neural stimulation system provides, via the speaker, audio stimulation having a second value of the second parameter. A stimuli orchestration component selects, for a first time interval, one of the visual stimulation or the audio stimulation to vary based on a policy, selects, for the first time interval, the other of the visual stimulation or the audio stimulation to keep constant based on the policy, and provides causes the one of the visual neural stimulation system or the auditory neural stimulation system to vary the one of the visual stimulation or the audio stimulation.

Electronic devices are provided that can determine a head movement. A method comprises: acquiring, in response to a head movement performed by a user, myoelectricity information of an eye of the user; and determining information related to the head movement according to the myoelectricity information and at least one piece of reference information. A head movement can be identified according to the myoelectricity information, which helps improve accuracy of head movement identification.

Embodiments of the present disclosure relate to an electrode device to acquire, process and transmit physiological signals. The device eliminates the need for inconvenient wires attached at different locations on patient's body. The device comprises a sensor patch comprising plurality of sensors/electrodes, configured to be in contact with a skin surface of a human body, to measure physiological of the patient. Also, the, device comprises a wire-free module,, embedded in the sensor patch, comprising an auto-orientation module to detect the orientation of the sensor patch on the human body using a plurality of sensors. The wire-free module comprises a processing module to process one or more signals received from the plurality of sensors/electrodes. Further, the wire-free module comprises a detection module to detect one or more processed signals as a predefined physiological signal and a transmission module to transmit the detected physiological signal to a mobile device.

A apparatus for detecting electrooculograph (EOG) signals, comprising: a pair of temple pieces connected to a bridging structure; at least one electrode on each temple piece configured to contact the skin at the temple, and to receive an EOG signal from a proximate orbital socket; a reference electrode displaced from each temple; and a processor configured to process signals from the sensors to detect saccade movements of the eyes. A wavelet-based algorithm permits analysis and coding of the saccade movements.

The present invention refers to the field of ophthalmology, and in particular to that of devices and methods for supporting the diagnosis of important eye pathologies such as Age-related Macular Degeneration (AMD), Diabetic Retinopathy (DR), anomalies and dysfunctions of the retina and of sight in general such as degeneration of the retinal structure of the optical nerve and of the visual cortex. More specifically, the invention concerns a new device and method for recording the electroretinogram (so-called ERG) of an eye, i.e. the bioelectric response of the retina induced by a light stimulus, through the eyelid.