A method and a system are disclosed for extracting important signal information. The method examines a group of signals obtained from testing of a patient's nervous system and finds a signal area of interest. Once a cluster of signals that all have the area of interest is found—the system concludes that the area of interest is located and validated. Signals that are not within the cluster are rejected and the signals within the cluster are signal-averaged to yield a signal-averaged waveform. The signal averaged waveform represents the results of the test.

A method and a system are disclosed for extracting important signal information. The method examines a group of signals obtained from testing of a patient's nervous system and finds a signal area of interest. Once a cluster of signals that all have the area of interest is found—the system concludes that the area of interest is located and validated. Signals that are not within the cluster are rejected and the signals within the cluster are signal-averaged to yield a signal-averaged waveform. The signal averaged waveform represents the results of the test.

Systems and methods of the present disclosure are directed to systems and methods for treating cognitive dysfunction in a subject in need thereof. The system can include eyeglasses, a photodiode positioned to detect ambient light, light sources, and an input device. The system can include a neural stimulation system that retrieves a profile and selects a light pattern having a fixed parameter and a variable parameter. The neural stimulation system can set a value of the variable parameter of the light pattern, construct an output signal, and then provide the output signal to the light sources to direct light towards the fovea.

A portable polysomnography apparatus comprises a unitary flexible structured pillow that is embedded with one or more sensors for data collection. The one or more sensors can comprise a tilt sensor that is configured to generate respiratory effort signals based on tilting of the head of the subject on the pillow. The one or more sensors can further be configured to generate ballistocardiogram signals from movement of the head of the subject caused by beating of the heart of the subject. The polysomnography apparatus can be advantageously sized and shaped to cause the sleeping subject to properly orient her head with respect to the sensors for optimal data collection while the subject is asleep.

A portable polysomnography apparatus comprises a unitary flexible structured pillow that is embedded with one or more sensors for data collection. The one or more sensors can comprise a tilt sensor that is configured to generate respiratory effort signals based on tilting of the head of the subject on the pillow. The one or more sensors can further be configured to generate ballistocardiogram signals from movement of the head of the subject caused by beating of the heart of the subject. The polysomnography apparatus can be advantageously sized and shaped to cause the sleeping subject to properly orient her head with respect to the sensors for optimal data collection while the subject is asleep.

The present invention relates to an eye movement measurement method including the steps of: (a) presenting standardized nystagmus test items and receiving am image of an eye in accordance with the standardized nystagmus test items; (b) recognizing a pupil and an iris from the image of the eye; (c) calculating amounts of horizontal and vertical changes of the pupil and an amount of torsional movement of the iris; (d) determining change values and orientations for three axis directions of the eye on the basis of the amounts of the horizontal and vertical changes of the pupil and the amount of the torsional movement of the iris; and (e) generating a diagnosis result for vertigo through deep learning modeling on the basis of the change values and orientations of the three axis directions of the eye.

According to one embodiment, an eye movement detecting device comprises first, second, third, fourth and fifth electrodes. A line connecting the first and the third electrodes passes through the right eye and a line connecting the second and the fourth electrodes passes through the left eye on at least one of a front view, a plan view or a side view. A distance between the fifth and the first electrodes is equal to a distance between the fifth and the second electrodes. A distance between the fifth and the third electrodes is equal to a distance between the fifth and the fourth electrodes. The detector respectively detects a horizontal movement of the right eye and a horizontal movement of the left eye.

According to one embodiment, an eye movement detecting device comprises first, second, third, fourth and fifth electrodes. A line connecting the first and the third electrodes passes through the right eye and a line connecting the second and the fourth electrodes passes through the left eye on at least one of a front view, a plan view or a side view. A distance between the fifth and the first electrodes is equal to a distance between the fifth and the second electrodes. A distance between the fifth and the third electrodes is equal to a distance between the fifth and the fourth electrodes. The detector respectively detects a horizontal movement of the right eye and a horizontal movement of the left eye.

A system and method for determining parameters of stimulation electrical signals for vagus nerve stimulation is discussed. Initial parameters of the signals are selected to provide reliable response to stimulation in physiological measurements of a subject. One or more physiological and neurological indices are determined based on a vagus nerve response model. For a selected vagus nerve activation, the electrical parameters of the signals are varied while monitoring changes in physiological parameters and values of the indices. The electrical parameters are varied until desired response in the physiological measurements and the values of the indices is observed. The electrical parameters are then stored as preferred parameters and can be used to activate the selected vagus nerve of the subject.

An apparatus and method for employing the macro- and micro-structure of sleep and similar states of consciousness to optimize pain-treatment are disclosed wherein an objective biomarker of pain-related sleep disturbance guides pain treatment from a sleep perspective. Furthermore, this concept can be extended to states of reduced consciousness such as coma or sedation. Additionally, it could be applied on individuals who are non-communicative due to injury, disease, language issues and/or infancy.