An apparatus and method for employing the macro- and micro-structure of sleep and similar states of consciousness to optimize pain-treatment are disclosed wherein an objective biomarker of pain-related sleep disturbance guides pain treatment from a sleep perspective. Furthermore, this concept can be extended to states of reduced consciousness such as coma or sedation. Additionally, it could be applied on individuals who are non-communicative due to injury, disease, language issues and/or infancy.

The present invention discloses a method for determining a degree of response to a physical activity. Acquire a physical activity signal measured by a sensing unit in the physical activity. Determine first data of a first physical activity feature set based on the physical activity signal. Determine a recognition of the degree of response to the physical activity based on the first data of the first physical activity feature set by a mathematical model describing a relationship between the first physical activity feature set and the degree of response to a physical activity. A portion of a first mechanism of the mathematical model adopts at least one portion of a second mechanism of a first neural network model associated with the second physical activity feature set.

In alternative embodiments, provided are products of manufacture, including devices and integrated systems, and methods, for reducing error-related negativity (ERN) and anxiety, and for treating or ameliorating Anxiety Disorders such as Generalized Anxiety Disorder (GAD) or Social Anxiety Disorder (SAD) and obsessive-compulsive disorder (OCD).

In alternative embodiments, provided are products of manufacture, including devices and integrated systems, and methods, for reducing error-related negativity (ERN) and anxiety, and for treating or ameliorating Anxiety Disorders such as Generalized Anxiety Disorder (GAD) or Social Anxiety Disorder (SAD) and obsessive-compulsive disorder (OCD).

The present invention provides reagents and methods for modulating cone photoreceptor activity, and devices for assessment of cone photoreceptor activity.

The present invention provides reagents and methods for modulating cone photoreceptor activity, and devices for assessment of cone photoreceptor activity.

A pixel light source apparatus, system and method are disclosed for a stimulus source for visual pathway testing. A representative system includes a plurality of pixel light sources and a control and driver circuit. The pixel light sources are coupled to each other to form a partially-spherical dome, with each pixel light source arranged to emit light directed to a convergent location of the partially-spherical dome. The control and driver circuit implements a selected stimulus protocol to selectively energize each pixel light source to generate light stimulation to any arbitrary or selected portion of the retina of an eye of a human subject. A representative pixel light source comprises at least one elongated and optically opaque side wall; a rear wall; an illumination source; a first optical element defining a first light chamber; and a second optical element defining a second light chamber.

A pixel light source apparatus, system and method are disclosed for a stimulus source for visual pathway testing. A representative system includes a plurality of pixel light sources and a control and driver circuit. The pixel light sources are coupled to each other to form a partially-spherical dome, with each pixel light source arranged to emit light directed to a convergent location of the partially-spherical dome. The control and driver circuit implements a selected stimulus protocol to selectively energize each pixel light source to generate light stimulation to any arbitrary or selected portion of the retina of an eye of a human subject. A representative pixel light source comprises at least one elongated and optically opaque side wall; a rear wall; an illumination source; a first optical element defining a first light chamber; and a second optical element defining a second light chamber.

Disclosed is an electronic device including a plurality of electrodes selectively connectable to a touch sensor or one or more biometric sensors; and a processor configured to receive a user input through the plurality of electrodes in a state in which the touch sensor and the plurality of electrodes are connected; perform an operation relating to the touch sensor when where the user input satisfies a first condition; connect the plurality of electrodes to the one or more biometric sensors when where the user input satisfies a second condition; and obtain a plurality of pieces of biometric information according to a pre-determined sequence through the plurality of electrodes connected with the one or more biometric sensors.

The present specification describes methods and systems for tracking vision performance, using various techniques such as and not limited to electrooculography. A modular device is integrated with frames of eyeglasses that can be worn by a user. The device incorporates one or more biosensors such as EOG sensors. EOG recording may be used to estimate eyelid and eye motion, and eye gaze direction. The modular device may be fitted into new eyewear or retrofitted into existing eyewear for tracking eyes of the wearer. Embodiments of the present specification provide systems and methods to enable seamless integration of eye tracking into everyday life to maximize productivity and performance.