Aspects of the present disclosure provide methods, apparatuses, and systems for closed-loop sleep protection and/or sleep regulation. According to an aspect, sleep disturbing noises are predicted and a biosignal parameter is measured to dynamically mask predicted disturbing environmental noises in the sleeping environment with active attenuation. Environmental noises in a sleeping environment of a subject are detected, input, or predicted based on historical data of the sleeping environment collected over a period of time. The biosignal parameter is used to determine sleep physiology of a subject. Based on the environmental noises in the sleeping environment and the determined sleep physiology, the noises are predicted to be disturbing or non-disturbing noises. For predicted disturbing noises, one or more actions are taken to regulate sleep and avoid sleep disruption by using sound masking prior to or concurrently with the occurrence of the predicted disturbing noises.

The present invention provides a method of conducting a sleep analysis by collecting physiologic and kinetic data from a subject, preferably via a wireless in-home data acquisition system, while the subject attempts to sleep at home. The sleep analysis, including clinical and research sleep studies and cardiorespiratory studies, can be used in the diagnosis of sleeping disorders and other diseases or conditions with sleep signatures, such as Parkinson's, epilepsy, chronic heart failure, chronic obstructive pulmonary disorder, or other neurological, cardiac, pulmonary, or muscular disorders. The method of the present invention can also be used to determine if environmental factors at the subject's home are preventing restorative sleep.

The present invention provides a method of conducting a sleep analysis by collecting physiologic and kinetic data from a subject, preferably via a wireless in-home data acquisition system, while the subject attempts to sleep at home. The sleep analysis, including clinical and research sleep studies and cardiorespiratory studies, can be used in the diagnosis of sleeping disorders and other diseases or conditions with sleep signatures, such as Parkinson's, epilepsy, chronic heart failure, chronic obstructive pulmonary disorder, or other neurological, cardiac, pulmonary, or muscular disorders. The method of the present invention can also be used to determine if environmental factors at the subject's home are preventing restorative sleep.

A method for picking up body signals from the head of a user comprises a) placing first and second electrodes on first and second different positions at a first side of the user's head in direct or capacitive contact with the user's head, said first side comprising a first eye of the user, the first and second electrodes being configured to pick up first and second electric potentials, respectively, from the user's body, and b) providing an Electrooculography signal representative of a corneo-retinal potential difference of said first eye of the user in dependence of said at first and second electric potentials. The first and second positions may be (substantially) located in a plane including the first eye of the user. A portable electronic device providing an Electrooculography signal, and a hearing device utilizing an Electrooculography signal is further disclosed.

An ultrasound imaging system can include first and second ultrasound transducer arrays and a processor circuit, coupled to the first and second ultrasound transducer arrays. The processor circuit can be configured to generate separate first and second volumetric ultrasound image data sets using the first and second ultrasound transducer arrays respectively and configured to combine the separate first and second volumetric ultrasound image data sets to generate an integrated volumetric image.

An ultrasound imaging system can include first and second ultrasound transducer arrays and a processor circuit, coupled to the first and second ultrasound transducer arrays. The processor circuit can be configured to generate separate first and second volumetric ultrasound image data sets using the first and second ultrasound transducer arrays respectively and configured to combine the separate first and second volumetric ultrasound image data sets to generate an integrated volumetric image.

Techniques to detect a non-alert state of a user may include receiving sensor data from an ear-worn electronic device disposed at least partially in the ear of a user, determining an alertness state of the user based on the sensor data, and providing alert data in response to the alertness state comprising a non-alert state to a user stimulation interface of the ear-worn electronic device or to an external device.

There is disclosed a method and system for predicting a likelihood that a patient is subject to one or more conditions. Retinal signal data corresponding to the patient may be received. Retinal signal features may be extracted from the retinal signal data. Descriptors may be extracted from the retinal signal features. The descriptors may be applied to a first mathematical model and a second mathematical model. The first mathematical model may correspond to a first condition. The second mathematical model may correspond to second condition. A first predicted probability for the first condition may be generated. A second predicted probability for the second condition may be generated. The first predicted probability and the second predicted probability may be output.

An example system includes an analyzer to determine a first distance between (1) a first peak in a first frequency band of first neuro-response data gathered from a subject while exposed to media and (2) a second peak in the first frequency band; determine a second distance between (1) a third peak in the first frequency band and either (2) the second peak in the first frequency band or (3) a fourth peak in the first frequency band and determine a first difference between the first distance and the second distance. The example system includes a selector to determine a modification for the media based on the first difference and a modifier to implement the modification for presentation of the media.

The present invention relates to a physiological recording electrode, and, more particularly, to an EEG (electroencephalography) recording electrode that can be used without the need for numerous steps in preparing the subject's skin and the electrode itself. The invention further relates to a surface feature or penetrator with a size and shape which that will not bend or break, which limits the depth of application, and/or anchors the electrode or other device during normal application; and a packaging system comprising a well and electrolytic fluid for maintaining a coating of said electrolytic fluid on the surface feature or penetrator.