A system and method are provided that allow a practitioner to rotate a human subject's head in three-dimensional space using a robotic arm with a head mount attached to one end, while the subject is focused on a visual target. The robotic arm is controlled by a computer system operatively coupled to the various sensors and drive motors embedded with the robotic arm.

According to an aspect of the present inventive concept there is provided a method for eye tracking, comprising: capturing a sequence of digital images of an eye of a user; outputting data including said sequence of images to an image processing unit; processing said data by the image processing unit to determine a sequence of positions of the eye, each position being indicative of a gaze direction, acquiring biosignal data representing an activity of the eye; and in response to detecting closing of the eye based on the acquired biosignal data, pausing at least one of said capturing, said outputting and said processing. A system for implementing the method is also disclosed.

In some embodiments, a display system comprising a head-mountable, augmented reality display is configured to perform a neurological analysis and to provide a perception aid based on an environmental trigger associated with the neurological condition. Performing the neurological analysis may include determining a reaction to a stimulus by receiving data from the one or more inwardly-directed sensors; and identifying a neurological condition associated with the reaction. In some embodiments, the perception aid may include a reminder, an alert, or virtual content that changes a property, e.g. a color, of a real object. The augmented reality display may be configured to display virtual content by outputting light with variable wavefront divergence, and to provide an accommodation-vergence mismatch of less than 0.5 diopters, including less than 0.25 diopters.

Wearable apparatus for monitoring various physiological and environmental factors are provided. Real-time, noninvasive health and environmental monitors include a plurality of compact sensors integrated within small, low-profile devices, such as earpiece modules. Physiological and environmental data is collected and wirelessly transmitted into a wireless network, where the data is stored and/or processed.

Embodiments in accordance with the present disclosure are directed to methods and apparatuses used for slow wave activity (SWA) optimization. An example method includes receiving one or more bio-signals from a user and classifying sleep stages by processing the bio-signals. The method further include determining dominant peripheral nervous system (PNS) oscillations based on the bio-signals and as a function of time and stage of sleep, and characterizing at least one property of the dominant PNS oscillations, including a phase, a phase shift, an amplitude, and/or frequency. The method further include providing an indication of an optimal window for maximizing SWA generation based on the phase, the phase shift, the amplitude, or the frequency. The indication is provided to stimulation circuitry that delivers stimulation to the user within the optimal window. Feedback is provided responsive to the stimulation based on an EEG signal of the user.

Disclosed is a layered body comprising a polymer comprising repeating units having the general structure CH.sub.2CHR.sup.1COOR.sup.2 as defined herein, to a process for producing such a layered body, to a layered body produced by that process and to the use of a layered body for electrophysical measurements.

Systems and methods of the present disclosure are directed to systems and methods for treating cognitive dysfunction in a subject in need thereof. The system can include a light source and a speaker. A visual neural stimulation system provides, via the light source, visual stimulation having a first value of a first parameter. An auditory neural stimulation system provides, via the speaker, audio stimulation having a second value of the second parameter. A stimuli orchestration component selects, for a first time interval, one of the visual stimulation or the audio stimulation to vary based on a policy, selects, for the first time interval, the other of the visual stimulation or the audio stimulation to keep constant based on the policy, and provides causes the one of the visual neural stimulation system or the auditory neural stimulation system to vary the one of the visual stimulation or the audio stimulation.

Methods and systems are provided to monitor bio-signals associated with one or more physiological structures of a subject, process the bio-signals to determine neural information, determine a current state of the subject based on the neural information, determine feedback to be provided to the subject based on the current neural state and a desired neural state, and/or to provide the feedback to the subject in order to modify the subject's current neural state to the desired neural state. The neural information may include validated neural indices relating to dynamic regulation of the monitored physiological structures via identifiable neural pathways and/or neural metrics quantified from such neural indices.

The invention relates to a self-contained device (1) for stimulating slow brain waves, capable of being worn by a person (P), in particular during a period of time when said person is sleeping. The device (1) comprises a supporting element (2), capable of surrounding the head of a person, and on which electrodes (3) are mounted in contact with the person in order to acquire a measurement signal that represents a physiological electrical signal of the person; an acoustic transducer (4) for emitting an acoustic signal (A) stimulating the inner ear of the person; and on-board conditioning and control electronics (5) for, in flexible real time, receiving the measurement signal and controlling the emission of an acoustic signal (A) synchronised with a predefined slow brain wave time pattern.

A method for providing electrical stimulation to a user as a user performs a set of tasks during a time window, the method comprising: providing an electrical stimulation treatment, characterized by a stimulation parameter and a set of portions, to a brain region of the user in association with the time window; for each task of the set of tasks: receiving a signal stream characterizing a neurological state of the user; from the signal stream, identifying a neurological signature characterizing the neurological state associated with the task; and modulating the electrical stimulation treatment provided to the brain region of the user based upon the neurological signature, wherein modulating comprises delivering a portion of the set of portions of the electrical stimulation treatment to the brain region of the user, while maintaining an aggregate amount of the stimulation parameter of the treatment provided during the time window below a maximum limit.