According to one embodiment, an eye movement detecting device comprises first, second, third, fourth and fifth electrodes. A line connecting the first and the third electrodes passes through the right eye and a line connecting the second and the fourth electrodes passes through the left eye on at least one of a front view, a plan view or a side view. A distance between the fifth and the first electrodes is equal to a distance between the fifth and the second electrodes. A distance between the fifth and the third electrodes is equal to a distance between the fifth and the fourth electrodes. The detector respectively detects a horizontal movement of the right eye and a horizontal movement of the left eye.

Injectable biophotonic sensors, systems relating to biophotonic sensors, and methods of using the injectable biophotonic sensors and systems are described. Methods and devices for delivering injectable biophotonic sensors to a subject are described. In an embodiment, an injectable biophotonic sensor comprises a printed circuit board (PCB); a light source; a first sensing element; a second sensing element; a receiver device or a induction coil; and an outer casing, wherein the first sensing element, the second sensing element, and the receiver device or the receiver induction coil are coupled to the PCB.

The present invention provides a method of conducting a sleep analysis by collecting physiologic and kinetic data from a subject, preferably via a wireless in-home data acquisition system, while the subject attempts to sleep at home. The sleep analysis, including clinical and research sleep studies and cardiorespiratory studies, can be used in the diagnosis of sleeping disorders and other diseases or conditions with sleep signatures, such as Parkinson's, epilepsy, chronic heart failure, chronic obstructive pulmonary disorder, or other neurological, cardiac, pulmonary, or muscular disorders. The method of the present invention can also be used to determine if environmental factors at the subject's home are preventing restorative sleep.

The present invention provides a method of conducting a sleep analysis by collecting physiologic and kinetic data from a subject, preferably via a wireless in-home data acquisition system, while the subject attempts to sleep at home. The sleep analysis, including clinical and research sleep studies and cardiorespiratory studies, can be used in the diagnosis of sleeping disorders and other diseases or conditions with sleep signatures, such as Parkinson's, epilepsy, chronic heart failure, chronic obstructive pulmonary disorder, or other neurological, cardiac, pulmonary, or muscular disorders. The method of the present invention can also be used to determine if environmental factors at the subject's home are preventing restorative sleep.

An illustrative system includes a stimulation device configured to apply stimulation to a recipient, a sensing device configured to detect a physiological condition of the recipient, and a processing unit communicatively coupled to the stimulation device and the sensing device. The processing unit determines a stimulation strategy that is customized to the recipient and includes stimulation frames and stimulation gaps. The processing unit then directs the stimulation device to apply the stimulation to the recipient in accordance with the stimulation strategy by applying the stimulation only during time that corresponds to the stimulation frames. The processing unit also directs the sensing device to detect the physiological condition of the recipient in accordance with the stimulation strategy by detecting only during time that corresponds to the stimulation gaps. Based on the detected physiological condition, the processing unit performs an action. Corresponding systems, methods, and apparatuses are also disclosed.

An illustrative system includes a stimulation device configured to apply stimulation to a recipient, a sensing device configured to detect a physiological condition of the recipient, and a processing unit communicatively coupled to the stimulation device and the sensing device. The processing unit determines a stimulation strategy that is customized to the recipient and includes stimulation frames and stimulation gaps. The processing unit then directs the stimulation device to apply the stimulation to the recipient in accordance with the stimulation strategy by applying the stimulation only during time that corresponds to the stimulation frames. The processing unit also directs the sensing device to detect the physiological condition of the recipient in accordance with the stimulation strategy by detecting only during time that corresponds to the stimulation gaps. Based on the detected physiological condition, the processing unit performs an action. Corresponding systems, methods, and apparatuses are also disclosed.

A system and method for determining parameters of stimulation electrical signals for vagus nerve stimulation is discussed. Initial parameters of the signals are selected to provide reliable response to stimulation in physiological measurements of a subject. One or more physiological and neurological indices are determined based on a vagus nerve response model. For a selected vagus nerve activation, the electrical parameters of the signals are varied while monitoring changes in physiological parameters and values of the indices. The electrical parameters are varied until desired response in the physiological measurements and the values of the indices is observed. The electrical parameters are then stored as preferred parameters and can be used to activate the selected vagus nerve of the subject.

A sleep-aiding audio signal updating method and apparatus in the artificial intelligence (AI) field is provided. The method includes: obtaining a first biological signal collected when a first audio signal in a sleep-aiding audio library is played, where the first biological signal is a biological signal of a first user; determining a sleep quality of the first user based on the first biological signal; and updating the sleep-aiding audio library based on the sleep quality of the first user, so that a sleep-aiding audio signal can be updated, to provide a proper sleep-aiding audio signal for a user, and ensure a sleep-aiding effect.

The present specification relates to a contact lens having an integrated light source for electroretinography and a method for preparing same, the contact lens, having an integrated light source for electroretinography, comprising: a light source; a scattering material for scattering light from the light source; and an electrode for measuring changes in the electroretinogram due to the stimulation from the light source.

The present specification relates to a contact lens having an integrated light source for electroretinography and a method for preparing same, the contact lens, having an integrated light source for electroretinography, comprising: a light source; a scattering material for scattering light from the light source; and an electrode for measuring changes in the electroretinogram due to the stimulation from the light source.