Systems, methods, and computer readable media for determining cognitive impairment (CI) in patients are provided herein. Various regional structural-functional parameters of the retina can serve as biomarkers for the detection of CI. The method can include forming a database including a quantification of retinal structure and retinal function of a plurality of eyes associated with a plurality of patients, providing a baseline cognitive impairment (CI) reference. The method can include determining a measure of functionality of neurons in the retina based on an electroretinogram (ERG) of a patient. The method can include determining a structural measure of the first retina based on a generalized dimension spectrum and singularity spectrum of the skeletonized retinal image, and a lacunarity parameter of the skeletonized retinal image. The method can include determining a level of cognitive impairment based on the structural and functional measures.

Systems, devices, methods, and kits for monitoring one or more physiologic and/or physical signals from a subject are disclosed. A system including a head mounted display to monitor one or more physiologic signals from the face or head of the subject is disclosed. A method for analyzing an ocular parameter of the subject to determine a sympathetic and a parasympathetic outflow thereto is disclosed.

A vibration module for applying vibrational tractions to a wearer's skin is presented. Use of the vibration module in headphones is illustrated for providing tactile sensations of low frequency for music, for massage, and for electrical recording and stimulation of the wearer. Damped, planar, electromagnetically-actuated vibration modules of the moving magnet type are presented in theory and reduced to practice, and shown to provide a substantially uniform frequency response over the range 40-200 Hz with a minimum of unwanted audio.

The present disclosure provides an apparatus including a lens housing coupled to a lens assembly, a first lens disposed in a first end of the lens housing, a lens holder disposed in a second end of the lens housing, a lens aligner coupled to the lens assembly, and an optical element. The optical element is insertable laterally into the lens assembly to adjust a transverse position of the first lens and the second lens based on a thickness of the optical element to align a first axis of the first lens and the second lens to a second axis of a third lens positioned in the lens assembly for imaging an eye.

The present disclosure provides an apparatus including a lens housing coupled to a lens assembly, a first lens disposed in a first end of the lens housing, a lens holder disposed in a second end of the lens housing, a lens aligner coupled to the lens assembly, and an optical element. The optical element is insertable laterally into the lens assembly to adjust a transverse position of the first lens and the second lens based on a thickness of the optical element to align a first axis of the first lens and the second lens to a second axis of a third lens positioned in the lens assembly for imaging an eye.

Provided is an electrode member 1 to be attached to a body surface of a user, and includes an adhesion part 2 including a through hole 23 near a center and capable of adhering to a body surface of a user, an electrode 3 inserted into the through hole of the adhesion part, and a first retention part 4A configured to retain a solution for dissolving sebum C, in which a flow channel R including a gap is formed between an inner peripheral surface of the through hole of the adhesion part and the electrode, and the solution for dissolving sebum retained in the first retention part is able to flow out from one end side of the through hole through the flow channel.

A head-mounted device may have a head-mounted housing. The head-mounted housing may have displays that overlap a user's eyes and/or speakers that provide sound to the user's ears. The head-mounted housing may have transparent lenses that overlap the eyes of the user or may have opaque structures that prevent ambient light from reaching the user's eyes. The head-mounted device may have a geographic location sensor such as a satellite navigation system sensor and may include an orientation sensor such as an inertial measurement unit. The direction of a user's gaze relative to the head mounted device may be measured using an electrooculographic sensor. Electrodes in the electrooculographic sensor may measure signals resulting from the standing potential between the retina and cornea in the eye. Facial expressions and eye blinks may affect the signals detected with the electrodes and can be monitored during operation.

A head-mounted device may have a head-mounted housing. The head-mounted housing may have displays that overlap a user's eyes and/or speakers that provide sound to the user's ears. The head-mounted housing may have transparent lenses that overlap the eyes of the user or may have opaque structures that prevent ambient light from reaching the user's eyes. The head-mounted device may have a geographic location sensor such as a satellite navigation system sensor and may include an orientation sensor such as an inertial measurement unit. The direction of a user's gaze relative to the head mounted device may be measured using an electrooculographic sensor. Electrodes in the electrooculographic sensor may measure signals resulting from the standing potential between the retina and cornea in the eye. Facial expressions and eye blinks may affect the signals detected with the electrodes and can be monitored during operation.

The present invention relates to a physiological recording electrode, and, more particularly, to an EEG (electroencephalography) recording electrode that can be used without the need for numerous steps in preparing the subject's skin and the electrode itself. The invention further relates to a surface feature or penetrator with a size and shape which that will not bend or break, which limits the depth of application, and/or anchors the electrode or other device during normal application; and a packaging system comprising a well and electrolytic fluid for maintaining a coating of said electrolytic fluid on the surface feature or penetrator.

Configurations are disclosed for a health system to be used in various healthcare applications, e.g., for patient diagnostics, monitoring, and/or therapy. The health system may comprise a light generation module to transmit light or an image to a user, one or more sensors to detect a physiological parameter of the user's body, including their eyes, and processing circuitry to analyze an input received in response to the presented images to determine one or more health conditions or defects.