Apparatus, systems, and methods for monitoring a sensor module mounted in a sensor platform, wherein the sensor platform includes an adhesive side and a pocket, wherein the pocket is designed to receive the sensor module, to facilitate sensing by the sensor module of physiological attributes, and to allow insertion and removal of the sensor device from the pocket.

Methods for treating a human patient diagnosed with cancer with therapeutic neuromodulation and associated systems are disclosed herein. Sympathetic nerve activity can contribute to several cellular and physiological processes associated with the progression of cancer. One aspect of the present technology is directed to methods that attenuate neural traffic along target sympathetic nerves innervating tissue proximate a primary malignant tumor. Other aspects are directed to methods that at least partially inhibit sympathetic neural activity in a renal nerve of a patient diagnosed with cancer or who has a high risk of developing cancer. Targeted sympathetic nerve activity can be attenuated to improve a measurable physiological parameter corresponding to the progression of cancer in the patient. The attenuation can be achieved, for example, using an intravascularly positioned catheter carrying a therapeutic assembly, e.g., a therapeutic assembly configured to use electrically-induced, thermally-induced, and/or chemically-induced approaches to modulate the target sympathetic nerve.

A biological information measuring apparatus according to an embodiment includes a calculating unit and a measuring unit. The calculating unit is configured to calculate information related to a pulse wave of a subject, on the basis of luminance information of a picture signal of the subject. The measuring unit is configured to measure a fluctuation of blood pressure of the subject based on an increase or a decrease in the information related to the pulse wave, in accordance with a site of the subject from which the picture signal was obtained.

A cardiovascular health assessment score, representing a working tissue flow and indicating the dependence on central and peripheral control mechanisms, is generated by an evaluation system and used to support a variety of individualized medicine and health applications. One or more of the individualized medicine and health applications may be implemented as part of the evaluation system and incorporate the cardiovascular health assessment.

Apparatus for electrophysiological studies comprises: at least one output channel (206); a plurality of detection channels (210, 212, 214); and control means (202). The at least one output channel includes a stimulation channel. The control means (202) is arranged to provide a stimulation signal to the stimulation channel and to process detection signals from the detection channels thereby to identify ectopy events in the detection signals.

An orthostatic hypotension screening system using a heart rate-based machine learning algorithm includes an input unit configured to receive a variable comprising at least one of a patient's age, blood pressure, an expiration (E)-inspiration (I) difference and an E:I ratio calculated from a heart rate, and a Valsalva ratio calculated according to a Valsalva method; and a determination unit configured to determine whether the patient has orthostatic hypotension according to a machine learning algorithm that is pre-trained based on the variable received through the input unit.

An analysis system and method are provided for analyzing physical information and acquiring biological data of a user from a biological data acquisition sensor. The exemplary analysis system includes a circadian rhythm calculator that calculates an average circadian rhythm of the user; an autonomic nerve analyzer that performs autonomic nerve analysis based on a variation in the biological data; and a physical information analyzer that weights an autonomic nerve analysis result analyzed by the autonomic nerve analyzer with a weighting coefficient set based on a measurement time at which the biological data of the user is acquired and a cycle of the average circadian rhythm. The physical information analyzer also estimates a change in a circadian rhythm with respect to the average circadian rhythm based on the weighted autonomic nerve analysis result.

Devices and methods are disclosed that treat a medical condition, such as migraine headache, by electrically stimulating a nerve noninvasively, which may be a vagus nerve situated within a patient's neck. Preferred embodiments allow a patient to self-treat his or her condition. Disclosed methods assure that the device is being positioned correctly on the neck and that the amplitude and other parameters of the stimulation actually stimulate the vagus nerve with a therapeutic waveform. Those methods comprise measuring properties of the patient's larynx, pupil diameters, blood flow within an eye, electrodermal activity and/or heart rate variability.

Described herein is a method for identifying a farm animal having an impairment of regulative capacity in response to metabolic stress, the method including: a) assessing the value of the nonlinear domain heart rate variability component L.sub.MAX of a farm animal based on a heart beat interval data set obtained for the farm animal; and b) comparing the value of L.sub.MAX assessed according to (a) with a species specific threshold of L.sub.MAX, whereby a farm animal having an impairment of regulative capacity will be identified.

A phrenic nerve pacing monitor assembly for a cryogenic balloon catheter system used during a cryoablation procedure, which monitors movement of a diaphragm of a patient, includes a pacing detector and a safety system. The pacing detector directly monitors movement of the diaphragm of the patient to detect when phrenic nerve pacing is occurring. Additionally, the pacing detector generates monitor output based on the movement of the diaphragm of the patient. The safety system receives the monitor output and based at least in part on the monitor output selectively provides an alert when movement of the diaphragm of the patient is atypical. The safety system is configured to provide the alert only while at least one of (i) phrenic nerve pacing is occurring, and (ii) cryoablation is occurring.