Systems and methods for treating fibrous masses associated with conditions such as Morton's neuroma, stump neuroma, plantar fibroma, plantar fibromatosis, plantar fasciitis, plantar fasciopathy, and Achilles tendinopathy. According to implementation herein, exemplary methods may comprise non-surgically delivering electromagnetic energy to such fibrous masses in various ways.

Systems, devices, and techniques are described for analyzing evoked compound action potentials (ECAP) signals to assess the effect of a delivered electrical stimulation signal. In one example, a system includes a stimulation generator configured to deliver a stimulation pulse to a patient, sensing circuitry configured to sense an evoked compound action potential (ECAP) signal evoked from the stimulation pulse, and processing circuitry. The processing circuitry may be configured to determine a maximum value of a derivative of the ECAP signal, determine a minimum value of the derivative of the ECAP signal, determine, based on the maximum value of the derivative and the minimum value of the derivative, a characteristic value of the ECAP signal, and determine, based on the characteristic value of the ECAP signal, at least one parameter value at least partially defining electrical stimulation therapy to be delivered to the patient.

The present invention provides a neurological disorders decision support system that can assist an examiner to diagnose an examinee. The neurological disorders decision support system includes a user module, a screening module, an intelligent calculation module and a diagnosis module. The user module sends an inquiry to the examinee, receives a response message from the examinee, and retrieves a physiological characteristic signal of the examinee. The screening module executes a neurological examination application program to indicate to the examinee to obtain physiological characteristic signals. The screening module outputs response messages and physiological characteristic signals for the intelligent calculation module to execute an algorithm to generate an analysis report. The analysis report assists the examiner for diagnosis, and sends a diagnosis notification to the user module through the diagnosis module. The invention also provides a neurological disorders decision support method.

Embodiments of the present disclosure provide an apparatus, method and system for physical, pre-action, extremity and related spinal cord, brain stem and neural therapies. An apparatus according to the present disclosure can include: a computing device configured to convert an input control action into a simulation instruction, wherein the input control action is provided by an input device; at least one simulated extremity operatively connected to the computing device and configured to simulate at least one modeled human anatomical movement based on the simulation instruction, wherein the at least one modeled human anatomical movement is distinct from the input control action; and a feedback device operatively connected to the computing device and configured to transmit a sensory response, wherein the sensory response is based on the modeled human anatomical movement.

A neuropathy screening and severity system can comprise a contact probe comprising a probe housing having a predetermined weight and having an electromechanical actuator operable to vibrate at a variable amplitude and a frequency. The actuator can be operable to contact with a patient at a predetermined pressure based on the predetermined weight. The system can also comprise an electronic control unit disposed in the probe housing. The electronic control unit can be operable to ramp the variable amplitude of the electromechanical actuator from a first amplitude to a second amplitude over a sensory test time.

A nerve mapping system includes an energy based dissection device, a plurality of beacons, and a processing device. The plurality of beacons are disposed in a tissue of a patient. Each beacon is adapted to transmit one or more first electrical signals within the body and receive one or more second energy signals. The processing device is adapted to determine first locations associated with the plurality of beacons, a second location associated with the energy based dissection device, and a third location associated with a nerve within the tissue, based on the one or more second signals, generate a mapping of the first locations, second location, and third location, and cause the first locations, second location, and third location to be displayed on a display device.

Provided herein are methods, devices and compositions for assessing neuromodulation efficacy based on changes in the level of one or more biomarkers in plasma or urine collected from a human subject following a renal neuromodulation procedure.

A method and system to obtain and process data indicative of muscle reflexes for screening and/or diagnosing a patient with a brain injury or spinal cord injury, and especially for obtaining and processing data indicative of reflexes from the bulbospongiosus muscle. Certain embodiments employ a novel electromechanical probe for stimulating the bulbospongiosus muscle to identify a time of the stimulation so that electrical responses from electrodes on the patient's skin can be identified for analysis.

Systems, devices and methods are provided for neuromonitoring, particularly neuromonitoring to reduce the risks of contacting or damaging nerves or causing patient discomfort during and after surgical procedures, including spinal surgeries. The neuromonitoring procedures include monitoring for the presence of or damage to sensory nerves, and optionally includes additional monitoring for motor nerves. In some systems, including systems that monitor for both sensory and motor nerves, components of the monitoring systems (e.g., stimulating electrodes and response sensors), may be combined with one or more surgical instruments. The systems, devices, and methods provide for pre-surgical assessment of neural anatomy and surgical planning, intraoperative monitoring of nerve condition, and post-operative assessment of nerve position and health.

An intraoperative nerve monitoring system for monitoring nerve activity within a trachea of a patient. The intraoperative nerve monitoring system includes an endotracheal (ET) tube assembly, which includes an ET tube partially inserted within a trachea and a surface electrode wrapped about the ET tube. The ET tube is configured to monitor nerve activity when the ET tube is partially inserted within the trachea and is contacting a target tissue and to output a nerve signal. The intraoperative nerve monitoring system also includes a pressure sensor assembly configured to sense an amount of pressure between the surface electrode and the target tissue and a console including an output device configured to output indicators based on the monitored nerve activity and the sensed amount of pressure to facilitate proper placement of the ET tube in the trachea and to indicate nerve activity.