An imaging system includes a light source to emit a plurality of wavelengths of light, and a camera coupled to receive the light reflected back from tissue in a body. Also included are a database with reflectance data for a plurality of tissue types, and a controller coupled to the light source, the database, and the camera. The controller causes the imaging system to perform operations, including: generating image data with the camera; receiving the image data from the camera with the controller; comparing, with the controller, the image data to the reflectance data in the database; and determining a tissue type in the image data in response to comparing the image data to the reflectance data.

In one embodiment, the invention relates to systems, methods, and apparatus relating to the detection of a neuropathy such as a perioperative neuropathy. In one embodiment, a wristband comprising a plurality of anodes and cathodes is used. The wristband can be a component in a electrode array that includes a plurality of reference or recording electrodes. The electrode array can be configured to stimulate and collect responsive signals from an ulnar, a median, radial and posterior tibial nerve. The simulation and signal collection can be performed on a continuous basis for time periods of interest such as a given perioperative time period using a monitoring device.

Neuromuscular monitoring is described that uses a novel lead assembly and a monitor that can select the appropriate electrodes on the lead assembly and calibrate the stimulation signals applied to the patient through the lead assembly. The monitoring can also set a noise floor value to reduce the likelihood of an erroneous train of four calculations. The present system can automatically sense train of four response of a patient and reduce the likelihood of false train of four indications.

A pair of electronic shoe insoles aids an individual with peripheral neuropathy in walking without falling, despite the user having little or no sensation in her feet. Each insole uses a number of pressure sensors and provides various forms of biofeedback to the user such as auditory, haptic, and vibratory feedback which corresponds to the position of the user's foot on the ground. Vibration feedback is provided through vibration motors disposed against the soles of the user's feet at selected locations which correspond to locations of pressure sensors. This allows for direct neural stimulation of the sole of the foot at three biomechanically appropriate locations. Auditory and haptic feedback are provided through auxiliary devices that the user wears on appropriate parts of the body. Biofeedback transmitted through these mechanisms would correspond to change in foot position as detected by the pressure sensors. The shoe insoles may provide one or more of these forms of feedback, and other types of feedback may be provided by output devices as well. An embedded microcontroller wirelessly connected to a computer, tablet or phone permits an individual to monitor gait performance and to adjust numerous parameters of this biofeedback mechanism, such as time delays and strength of vibration or audio feedback. The device may also include a driving mode in which small variations of pressure on the gas pedal would be conveyed to the user through haptic and auditory feedback, thereby allowing the user to drive.

A device for measuring a neural response evoked by a stimulus. First and second sense electrodes are positioned at distinct locations along a neural pathway. A neural stimulus is applied and first and second recordings of a neural response evoked by the stimulus are obtained from the respective sense electrodes. The first recording and the second recording are compared to determine propagation properties of the evoked neural response.

A system for providing energy to a bio-implantable medical device includes an acoustic energy delivery device and a bio-implantable electroacoustical energy converter. The acoustic energy delivery device generates acoustic energy with a multi-dimensional array of transmitting electroacoustical transducers. The acoustic energy is received by one or more receiving electroacoustical transducers in the bio-implantable electroacoustical energy converter. The receiving electroacoustical transducers convert the acoustic energy to electrical energy to power the bio-implantable medical device directly or indirectly. An external alignment system provides lateral and/or angular positioning of an ultrasound energy transmitter over an ultrasound energy receiver. The acoustic energy transmitter alignment system comprises either or both x-y-z plus angular positioning components, and/or a substantially multi-dimensional array of transmitters plus position sensors in both the transmitter and receiver units.

Surgical access port stabilization systems and methods are described herein. Such systems and methods can be employed to provide ipsilateral stabilization of a surgical access port, e.g., during spinal surgeries. In one embodiment, a surgical system can include an access port configured for percutaneous insertion into a patient to define a channel to a surgical site and an anchor configured for insertion into the patient's bone. Further, the access port can be coupled to the anchor such that a longitudinal axis of the access port and a longitudinal axis of the anchor are non-coaxial. With such a system, a surgeon or other user can access a surgical site through the access port without the need for external or other stabilization of the access port, but can instead position the access port relative to an anchor already placed in the patient's body.

Adjustable-length surgical access devices are disclosed herein, which can advantageously allow an overall length of the access device to be quickly and easily changed by the user. The access devices herein can reduce or eliminate the need to maintain an inventory of many different length access devices. In some embodiments, the length of the access device can be adjusted while the access device is inserted into the patient. This can reduce or eliminate the need to swap in and out several different access devices before arriving at an optimal length access device. This can also reduce or eliminate the need to change the access device that is inserted into a patient as the depth at which a surgical step is performed changes over the course of a procedure. Rather, the length of the access device can be adjusted in situ and on-the-fly as needed or desired to accommodate different surgical depths.

Surgical visualization systems and related methods are disclosed herein, e.g., for providing visualization during surgical procedures. Systems and methods herein can be used in a wide range of surgical procedures, including spinal surgeries such as minimally-invasive fusion or discectomy procedures. Systems and methods herein can include various features for enhancing end user experience, improving clinical outcomes, or reducing the invasiveness of a surgery. Exemplary features can include access port integration, hands-free operation, active and/or passive lens cleaning, adjustable camera depth, and many others.

Embodiments of the invention are directed to a system for detecting neurotransmitters. A non-limiting example of the system includes a porous electrode. A system can also include a pH sensor attached to the porous electrode, wherein the pH sensor includes a sensing electrode and a reference electrode. The system can also include electronic circuitry in communication with the pH sensor.