Various methods and embodiments of the present technology generally relate to neural spike sorting in real-time. More specifically, some embodiments relate to a real-time neural spike sorting process using distributed nodes and edges to form clusters in the vector space to learn the neural spike data distribution adaptively for neural spike classification in real-time. The state of the brain or the onset of a neurological disorder can be determined by analyzing the neural spike firing pattern, and the first stage of the neural data analysis is to sort the recorded neural spikes to their originating neurons. Methods that can sort the recorded neural spikes in real-time with low system latency and can be implemented with resource limited digital electronic hardware, including a Field-Programming Gate Array (FPGA), an Application-Specific Integrated Circuit and an embedded microprocessor, are beneficial in understanding neuronal networks and controlling neurological disorders.

A system for computer-aided triage includes a router, a remote computing system, and a client application. A method for computer-aided triage includes receiving a data packet associated with a patient and taken at a point of care; checking for a suspected condition associated with the data packet; in an event that the suspected condition is detected, determining a recipient based on the suspected condition; and transmitting information to a device associated with the recipient.

Universal switch modules, universal switches, and methods of using the same are disclosed, including methods of preparing an individual to interface with an electronic device or software. For example, a method is disclosed that can include measuring brain-related signals of the individual to obtain a first sensed brain-related signal when the individual generates a task-irrelevant thought. The method can include transmitting the first sensed brain-related signal to a processing unit. The method can include associating the task-irrelevant thought and the first sensed brain-related signal with N input commands. The method can include compiling the task-irrelevant thought, the first sensed brain-related signal, and the N input commands to an electronic database.

A surgical access assembly and method of use is disclosed. The surgical access assembly comprises an outer sheath and an obturator. The outer sheath and obturator are configured to be delivered to an area of interest within the brain. Either the outer sheath or the obturator may be configured to operate with a navigational system to track the location of either within the brain. Once positioned at a desired location, the obturator is removed, leaving a distal end of the outer sheath adjacent an area of interest, and creating a working corridor. Interrogation of the area of interest may be performed to evaluate a disorder and/or abnormality, as well as evaluate treatment regimes. Interventional devices may also be introduced to the area of interest, as well as a variety of treatments.

A method of localizing brain regions for the purpose of guiding placement of electrodes and related implants is disclosed. The inventive method involves effecting a pulse in a patient's brain, temporally aligning readings taken from an electrode at various depths, measuring local field potentials at each depth during interstimulus intervals, performing a coherence analysis comparing the local field potential measurements of the different depths, and determining a corresponding brain region for the depths compared.

A method for prediction of a head impact event mechanism via an instrumented mouthguard device comprises receiving, as input, time series data representative of a head impact event, wherein the time series data is derived from the instrumented mouthguard device. The instrumented mouthguard device includes one or more accelerometers. The method further comprises generating an array of spatial coordinates representing points on a computer head model, and processing the time series data to determine a direction of impact and location of impact relative to the computer head model.

The present disclosure describes a method for neuromodulating a subject, comprising providing (i) a cognitively engaging content, and (ii) a gamma oscillation inducing waveform, wherein said gamma oscillation inducing waveform: comprises an intensity that renders said gamma oscillation inducing waveform imperceptible to said subject; and causes a therapeutic improvement in a cognitive function, thereby neuromodulating said subject.

Systems and methods for evaluating neurologic function of a subject are described. An odorant, auditory and/or somatosensory generator is configured to deliver a sensory stimulation to the subject, a plurality of electrodes are configured to be attached to the subject, and a handheld EEG control unit is configured to control the odorant, auditory and/or somatosensory generator, process the neural signals from the plurality of electrodes and generate an assessment of neurologic function of the subject.

A rehabilitation work support apparatus, a rehabilitation work support method, and a program capable of efficiently managing patient's actual current ability values are provided. A rehabilitation work support apparatus (1) includes a change prediction unit (2) that predicts whether or not an actual current ability value of a patient during a rehabilitation period has changed from a latest ability value of that patient stored in a storage device based on an elapsed time from a time of an evaluation of the latest ability value of the patient stored in the storage device, and a change prediction output unit (3) that performs control so as to output a result of the prediction made by the change prediction unit (2).

Systems, devices, methods, and computer-readable media may use broad-range spectrophotometric analysis and/or other sensors to generate data from bodily fluids accessed via a fluid drain. These data may be utilized to analyze therapeutic efficacy, to enable early detection of complications, and to guide the clinical management of patients being treated with a fluid drain. Advantageously, these systems, devices, methods, and computer-readable media enable clinical patient care decisions to be performed in a manner that is data-driven or quantitative in nature as opposed to qualitative—e.g., via well-defined, algorithmic-based processes and/or reliable methods. As a result, these systems, devices, methods, and computer-readable media enable improved clinical outcomes, more efficiently optimized medical care, and cost savings.