Methods and systems are disclosed herein for a system configured to determine a position of a brain monitoring user device, and a brain state of a user. Based on the determined position and the determined brain state, the system provides access to a set of media guidance application operations corresponding to the determined brain state and to brain regions corresponding to the determined position of the brain monitoring user device.

A method of transcranial brain optical imaging including obtaining a Laser Speckle (LS) image of cranial blood vessels of a subject, obtaining a Dynamic Fluorescence (DF) image of the cranial blood vessels of the subject, and combining the LS image and the DF image producing a combined color image which displays both structure of the cranial blood vessels and perfusion of blood along the cranial blood vessels. Related apparatus and methods are also described.

The present invention provides a removable optical imaging device cap for use with a near infrared (NIR) light optical imaging device for detecting intracranial hematoma.

The present application provides a method and an apparatus of actively sensing a neuronal firing frequency at a functional site in a brain, the method comprising: generating a varying electromagnetic field and acting a near field of the generated electromagnetic field on a targeted brain functional site; sensing the alteration of the electromagnetic field at the targeted brain functional site; and determining a variation frequency of the alteration of the electromagnetic field at the targeted brain functional site as the neuronal firing frequency at the targeted brain functional site.

An impact control system includes a supporting structure with gravity compensation mechanism, and a supporting bed which is supported by the supporting structure and supports an impact target. Here, the supporting structure includes an elastic element, a vertical support to which one end of the elastic element is fixed, a horizontal support to which the other end of the elastic element is fixed, and which is rotatable around a rotation axis disposed at one end of the horizontal support meeting an end of the vertical support, and a weight support part which is connected to the other end of the horizontal support and supports the supporting bed while contacting a lower surface of the supporting bed.

A system and method for identifying a patient-specific neurosurgery target location is provided. The system receives brain imaging data for a patient that includes tracts and networks in the patient brain, accesses a quantitative connectome atlas comprising population-based, disease-specific structural and functional connectivity maps comprising a pattern of tracts and networks associated with an optimal target area (OTA) identified from a population of patients, and defines the patient-specific neurosurgery target location based on a comparison between a pattern of the tracts and networks from the brain imaging data for the patient and the pattern of tracts and networks associated with the OTA identified from the population of patients in the quantitative connectome atlas. The quantitative connectome atlas comprises a disease-specific, population-based quantitative connectome atlas that identifies an optimal target location for treatment associated with a maximal clinical improvement for each disease in the population of patients.

An illustrative wearable system includes a head-mountable component configured to be worn on a head of a user and a processor. The head-mountable component includes a time-to-digital converter (TDC) configured to receive, during a predetermined event detection time window that commences in response to an application of a light pulse to a target, a signal triggered by an event in which a photodetector detects a photon of the light pulse after the light pulse reflects from the target, the signal configured to enable a GRO of the TDC. The TDC is further configured to measure, using the GRO, a time interval between when the event occurred and an end of the predetermined event detection time window. The processor is configured to determine, based on the time interval and the predetermined event detection time window, an arrival time of the photon at the photodetector.

A processing device receives signals associated with nerve impulses that are transmitted to the visual cortex of a subject in response to one or more visual stimuli provided to at least one eye of the subject. The processing device processes the received signals and generates digital image data from the processed received signals that is representative of the visual perception, by the subject, of the one or more visual stimuli. In certain embodiments, the processing device processes digital image data that is representative of a scene to convert the digital image data to a sequence of nerve impulses, and provides the sequence of nerve impulses to the visual cortex of a subject such that the subject visually perceives the scene.

The present disclosure relates to immunoassays for NF-L performed on liquid samples derived from physiological fluids such as venous blood to detect the presence or absence of a physiological condition by quantifying one or a combination of NF-L determinations at concentrations indicative of the condition.

A method of monitoring a user's neuronal activity (10) includes recording a user's behavioural output with a portable electronic device, such as a mobile cellphone. The user's behavioural output (14) is compared (18) with predefined behavioural outputs associated with known event-related neuronal activations (20). The user's event-related neuronal activation (22) is determined based upon the comparison so as to provide an indication of the user's neuronal activity.