In some examples, a device includes sensing circuitry configured to receive one or more signals from a patient and processing circuitry configured to determine a plurality of autoregulation state values associated with a plurality of blood pressure values based on the one or more signals. The processing circuitry is further configured to determine that a first autoregulation state value of the plurality of autoregulation state values is anomalous based on other autoregulation state values of the plurality of autoregulation state values. The processing circuitry is also configured to modify the first autoregulation state value in response to determining that the first autoregulation state value is anomalous and determine an autoregulation status of the patient based on the plurality of autoregulation state values including the modified first autoregulation state value.

Systems and methods for treating cancerous tumors (including glioblastoma multiforme (GBM)) with electrotherapy, such as deep brain stimulation (DBS) technology, as disclosed herein. One or more configurations can be generated based on a patients tumor characteristics. The selected configurations can be electrode configurations or settings for an electrical source coupled to the electrodes. The one or more configurations can be targeted for inhibiting cell growth process, such as to inhibit mitosis, immune suppression, or to inhibit DNA replication. Inhibition of cell growth processes can initiate death of the cancerous cells.

Magnetic field generating means (2) is disposed on a scalp (1) of a subject (P) and generates a magnetic field that is radiated from a north pole, passes through a cerebral cortex (3) of the subject (P) and returns to a south pole in a loop path. Magnetic field detecting means (5) is disposed on the scalp (1) and detects a change in the magnetic field (4) as a signal reflecting an activity status of the cerebral cortex (3).

A method for detecting evidence of a stroke in a patient may involve securing a volumetric integral phase-shift spectroscopy (VIPS) device to the patient's head, transmitting a first signal from a first transmitter of the VIPS device through a left hemisphere of the patient's brain to a receiver of the VIPS device, transmitting a second signal from a second transmitter of the VIPS device through a right hemisphere of the patient's brain to the receiver, and detecting the evidence of the stroke, with the VIPS device.

A cloud computing system is described that communicates with a virtual machine to reattach the face of a patient to brain imaging data before the brain imaging data is transmitted for display on a brain navigation system.

System for non-invasive measuring of an intracranial reserve space (ICRS) parameter of a mammalian subject, comprising a multi-frequency ultrasound probe configured, beginning at a start time, to emit and receive ultrasound waves into and from the subject's head and to produce a signal of brain tissue pulsation; an instrument configured to non-invasively partially occlude an internal jugular vein (IJV) starting at the start time and including a second ultrasound probe producing a second signal; and a computer system configured to receive the signal, the second signal and the start time, the computer system also configured, using one or more processors, to derive from the signal an intracranial brain tissue pulsation waveform and from the second signal images of the IJV, and to determine a length of time from the start time to a subsequent time at which the waveform is sufficiently compressed so as to exhibit a predefined decline in variability.

A non-invasive method of estimating intra-cranial pressure (ICP). The method including the steps of: a. non-invasively measuring pressure pulses in an upper body artery; b. determining central aortic pressure (CAP) pulses that correspond to these measured pressure pulses; c. identifying features of the ICP wave which denote cardiac ejection and wave reflection from the cranium, including Ejection Duration (ED) and Augmentation Index of Pressure (PAIx); d. non-invasively measuring flow pulses in a central artery which supplies blood to the brain within the cranium; e. identifying features of the measured cerebral flow waves which denote cardiac ejection and wave reflection from the cranium as Flow Augmentation Index (FAIx); f. calculating an ICP flow augmentation index from the measured central flow pulses; g. comparing the calculated ICP pressure augmentation index (PAIx) and flow augmentation index (FAIx) to measure (gender-specific) pressure and flow augmentation data indicative of a measured ICP to thereby estimate actual ICP; and h. noting any disparity between ED measured for pressure waves and ED measured for flow.

A system and method for assessing a patient's balancing ability in order to facilitate ascertaining the patient's current medical status. The system includes a balance plate for measuring the meter of gravity dynamic weight distribution in combination with a sensor for measuring the patient's fine motor skills.

A method and apparatus for stimulating neural activity in the brain of a user of an apparatus with a display screen by causing at least one portion of the display screen to flicker in a controlled manner and utilizing the apparatus to measure an effect on a user exposed to the flicker for a time.

The invention relates to a multi-step method with a number of processes and sub-processes that interact to allow for the selection, design and/or manufacture of a protective sports helmet for a specific player, or a recreational sports helmet for a specific person wearing the helmet. Once the desired protective sports helmet or recreational sports helmet is selected, information is collected from the individual player or wearer regarding the shape of his/her head and information about the impacts he/she has received while participating in the sport or activity. The collected information is processed to develop a bespoke energy attenuation assembly for use in the protective helmet. The energy attenuation assembly includes at least one energy attenuation member with a unique structural makeup and/or chemical composition. The energy attenuation assembly is purposely engineered to improve comfort and fit, as well as how the helmet responds when an impact or series of impacts are received by the helmet.