An exemplary wearable brain interface system includes a head-mountable component and a control system. The head-mountable component includes an array of photodetectors that includes a photodetector comprising a single-photon avalanche diode (SPAD) and a fast-gating circuit configured to arm and disarm the SPAD. The control system is for controlling a current drawn by the array of photodetectors.

A photovoltaic unit that includes a biological interface for sensing an electrical signal from the biological tissue, the biological interface including a multilayered piezoelectric amplifier including a composite impulse generating layer including a matrix of a piezo polymeric material and dispersed phases including piezo nanocrystals and carbon nanotubes. The photovoltaic unit also includes a transducer structure comprising a fiber substrate having quantum dots present on a receiving end of the fiber. The receiving end of the fiber receiving the electrical signal. The quantum dots converts the electrical signal to a light signal.

A brain response measurement system includes a stimulation timing control unit calculating, based on a delay time from a brain response to first stimulation in a first brain area to a brain response to a second stimulation in the first brain area, and a delay time from a brain response to the second stimulation in the second brain area to a brain response to the first stimulation in the second brain area, start and end times of the first stimulation and start and end times of the second stimulation that cause the brain response to the first stimulation in the first brain area and the brain response to the second stimulation in the first brain area not to overlap and cause the brain response to the second stimulation in the second brain area and the brain response to the first stimulation in the second brain area not to overlap.

Techniques are disclosed for measuring the corpus callosum volume of a fetus using magnetic resonance imaging. A scanogram of a fetus is acquired, and a detection area is determined using the corpus callosum position of the fetus in the scanogram. Magnetic resonance scanning is performed on the detection area to obtain a diffusion weighted image, with a gradient direction that is orthogonal or normal to an extending direction of fiber bundles of the corpus callosum. A fetal head image is cropped in the diffusion weighted image, and a predetermined threshold is applied to obtain an image including pixels having a brightness value that is greater than the threshold. Image processing is performed on the binarized image, with the largest region therein being identified as the corpus callosum, and the sum of voxel dimensions associated with the signal of the largest region being calculated as the corpus callosum volume.

An apparatus includes a plurality of particles, wherein each particle contains a plurality of magnetizable (for example, ferromagnetic) and ferroelectric materials in fixed physical relationship (for example, physical contact) with one another. A method and apparatus measure magnetic fields arising from or within the plurality of particles.

A method and a device for label-free all-optical neural regulation and imaging are provided. The method stimulates a neural activity through an infrared laser pulse, and acquires an optical scattered signal caused by the neural activity by optical coherence tomography (OCT) to realize label-free all-optical neural regulation and imaging. The method specifically includes: aiming an infrared laser at a target brain region, injecting a certain time series of laser pulses, synchronously scanning and imaging the target brain region by OCT, analyzing a relative change of an OCT scattered signal before and after laser stimulation, and acquiring a brain function signal based on OCT to realize synchronous neural regulation and imaging. The method and the device enable synchronous neural regulation and imaging without causing crosstalk between the regulation and imaging channels, and without the need for injection of a contrast agent or viral transfection.

The present invention relates to a suction instrument, more particularly a bipolar mapping suction instrument, for surgical purposes and to a system for suctioning fluids and tissue and for monitoring nerve tissue. The suction instrument comprises a cannula unit, which comprises an electrically conductive outer cannula tube, an electrically conductive inner cannula tube, and insulation. The electrically conductive inner cannula tube is electrically connected to a first pole of the bipolar electrical connection of the second interface. The electrically conductive inner cannula tube is arranged concentrically in the outer cannula tube which optionally can be insulated from the exterior. The electrically conductive inner cannula tube is mechanically connected to the handpiece and/or the first interface. The electrically conductive outer cannula tube is electrically connected to a second pole of the bipolar electrical connection of the second interface. The insulation is concentrically arranged between the outer cannula tube and the inner cannula tube. The insulation is configured to fully electrically isolate the outer cannula tube and the inner cannula tube in relation to one another.

A method and a system for measuring intra-site heterogeneity in a tumor using magnetic resonance imaging (MRI). The method includes acquiring magnetic resonance (MR) images using MRI modality; segmenting tumor sites in the MR images; dividing each of the tumor sites into a plurality of sub-regions; deriving image biomarkers from each voxel or pixel in the plurality of sub-regions; classifying each voxel or pixel in the plurality of sub-regions into genotypes or molecular subtypes based on the extracted image biomarkers and a classifier model including associations between image biomarkers and genotypes or molecule subtypes; creating a distribution of genotypes or molecular subtypes in the each of the plurality of sub-regions based on classifications of voxels or pixels; generating spatial information of genotypes or molecular subtypes in the tumor sites based on the distribution; and measuring intra-site heterogeneity in the tumor sites.

A measurement apparatus includes a light source, a sensor including light detection cells including a first light detection cell and a second light detection cell, and an electronic circuit. The circuit causes the light source to emit a light pulse, causes the first light detection cell to detect a reflected light pulse from a target in an exposure period including at least part of a period from when an intensity of the reflected light pulse starts increasing to when it starts falling and generate a first signal, causes the second light detection cell to detect the reflected light pulse in an exposure period including at least part of a trailing period from when the intensity of the reflected light pulse starts falling to when it stops falling and generate a second signal. The circuit generates, based on the first and second signals, data representing states of the target.

A system for concussion assessment, comprises a head mounted display and a remote AI host. The head mounted display is disposed for displaying at least one test image to a user and obtain a plurality of physiological data from the user. The remote AI host communicates with the head mounted display through a first network connection, so as to obtain a concussion assessment result according to the plurality of physiological data.