A system for assessing lower extremity movement quality includes one or more user sensors, at least one processor, and a movement evaluator implemented using the at least one processor. The movement evaluator is configured, by virtue of appropriate programming, for receiving movement data from the one or more user sensors during a user's performance of a movement task; extracting one or more movement features from the movement data, each movement feature characterizing a respective aspect of a movement pattern of the user's performance that is associated with lower extremity injury risk; and classifying the movement pattern into a classified risk category for lower extremity injury for the user based on the one or more movement features.

A bioelectrical signal measuring apparatus includes a mucosa contact electrode brought into contact with a nasal cavity mucosa or an oral cavity mucosa to apply a negative pressure and to measure a bioelectrical signal, an insertion tube, having one end supporting the mucosa contact electrode, inserted into a nasal cavity and bent, and a lead wire, connected to the mucosa contact electrode and connected to an amplifier disposed outside, extending in the insertion tube.

A method is provided for ophthalmic measurements, wherein the amount of a fluorophore is detected in ocular tissue and the obtained fluorescence signals are normalized by performing a ratio.

Methods and systems for determining whether brain tissue is indicative of a disorder, such as a neurodegenerative disorder, are provided. The methods and systems generally utilize data processing techniques to assess a level of congruence between measured parameters obtained from magnetic resonance imaging (MRI) data and simulated parameters obtained from computational modeling of brain tissues.

A system and kit for capturing a 3D image of a body a user includes a plurality of pillar segments being configurable between an assembled configuration and a disassembled configuration. In the assembled configuration, the pillar segments are joined to form one or more upstanding sensing pillars. A plurality of sensors operable to capture image data are distributed along the one or more sensing pillars. The plurality of sensors have fields of view that are overlapping when supported on the sensing pillars. In the disassembled configuration, transportation of the pillar segments is facilitated. The system and kit may be suitable for use at a remote location. Additional functionalities may include a power storage unit, solar charging panels, climate control subsystem, and wireless communication submodule. In operation, the sensing pillars may be enclosed within an enclosure.

Methods are provided for non-invasive early screening of a subject for a neurodegenerative disorder, by analyzing one or more parameters associated with the neurodegenerative disorder.

Provided herein is the design and synthesis of novel molecular rotor fluorophores useful for detection of amyloid or amyloid like proteins. The fluorophores are designed to exhibit enhanced fluorescence emission upon associating with amyloid or amyloid like proteins as compared to unbound compound. Also disclosed herein are methods for treating diseases associated with amyloid or amyloid like proteins.

The application generally relates to olfaction as a biomarker, more particularly as a prognostic biomarker or biological predictor, of neurosensory disease or disorder and/or of neurocognitive disease or disorder, in subjects whose nervous system has been infected by an infectious agent, such as by a neurotropic virus, bacterium, protozoan parasite, fungus or prion, more particularly by a neurotropic virus.

Stacked strain gauge sensors with increased electrical resistance are provided. In one aspect, a method of forming a stacked strain gauge sensor includes: forming multiple sensor layers, wherein the sensor layers include strain gauge sensor wires on substrates; forming holes in the substrates; stacking the sensor layers, one on top of another, to form a stack with the holes aligned in one or more locations forming through holes in the stack; and forming interconnects in the holes in one or more other locations interconnecting the strain gauges sensor wires between adjacent sensor layers to form a stacked strain gauge sensor. A stacked strain gauge sensor and method of use thereof are also provided.

In embodiments, devices, methods and systems to analyze the different mediums of brain function in a mathematically uniform manner may be provided. These devices, methods and systems may manifest at several levels and ways relating to brain physiology, including neuronal activity, molecular chirality and frequency oscillations. For example, in an embodiment, a computer-implemented method for determining structure of living neural tissue may comprise receiving at least one signal from at least one read modality, the signal representing at least one physical condition of the living neural tissue, determining action potentials based on the signals received from the read modalities, determining frequency oscillations based on the signals received from the read modalities and the action potentials, and determining neuron network structures based on the signals received from the read modalities, the action potentials, and the frequency oscillations.