The invention relates to a treatment apparatus for treating a gait irregularity of a person (1). The treatment apparatus (10) comprises a gait irregularity monitoring unit (11) for detecting a gait irregularity of the person, (a) cueing unit(s) (15, 16, 17), and a cueing control unit (14) for controlling the cueing unit(s) to provide, in response to the detection of the gait irregularity, a first cue set for treating the gait irregularity to the person. The gait irregularity monitoring unit monitors the effect of the providing of the first cue set to the person and determines whether the detected gait irregularity is being overcome. The cueing control unit controls the cueing unit(s) to provide a different second cue set to the person, if it has been determined that the detected gait irregularity has not been overcome. This improves the likelihood of being able to effectively treat the detected gait irregularity.

System, method and media for quantifying bulbar function of a subject. At a high level, embodiments of the invention measure and quantify bulbar function of a test subject based on video data, audio data, or other sensor data of a subject performing a test of bulbar function, such as speech, swallowing, and orofacial movements. This sensor data is then analyzed to identify key events such as syllable enunciations. Based on one or more characteristics of these key events (such as, for example, their rate, count, assessed accuracy, or trends over time), the bulbar function of the subject can accurately, reliably, and objectively be quantified.

A system for inhibiting shaking includes a plurality of parallel tracks each to join a plurality of mini gyroscopes in series, the parallel tracks joined at one or more control junctures and disposed on a flexible substrate wrap. The system also includes a plurality of mini gyroscopes spaced apart in series by each of the plurality of parallel tracks, the mini gyroscopes to spin about an axis relative to a single parallel track at a variable angular momentum. The system additionally includes a plurality of accelerometers to differentiate shaking and purposeful movement of portions of the flexible substrate wrap and provide output thereof and feedback on shaking ablation. The system further includes a controller to control the variable angular momentum and the spin axis of the mini gyroscopes to ablate shaking relative to purposeful movement of portions of the substrate wrap based on accelerometer output.

In embodiments, devices, methods and systems to analyze the different mediums of brain function in a mathematically uniform manner may be provided. These devices, methods and systems may manifest at several levels and ways relating to brain physiology, including neuronal activity, molecular chirality and frequency oscillations. For example, in an embodiment, a computer-implemented method for determining structure of living neural tissue may comprise receiving at least one signal from at least one read modality, the signal representing at least one physical condition of the living neural tissue, determining action potentials based on the signals received from the read modalities, determining frequency oscillations based on the signals received from the read modalities and the action potentials, and determining neuron network structures based on the signals received from the read modalities, the action potentials, and the frequency oscillations.

Provided herein are improved neural probes for detection and stimulation, including improved depth electrodes and cortical electrodes, along with various related improved components, devices, methods, and technologies.

A motion capture system includes a wearable device (e.g. a glove) suitable for being worn by a user and including one or more markers having respective colors. A video camera acquires a sequence of color frames of the user moving while wearing the glove, while a range camera acquires corresponding depth frames of the same scene. A processing unit processes both color frames and depth frames for reconstructing the 3D positions of the markers. In particular, the depth information provided by the depth frames are used for isolating a validity area within the color frames, and the markers are searched based on their colors, exclusively within the validity area of the color frames. The movements of the user are then captured as a sequence of positions of the markers. Combined use of color information and depth information provide a very reliable and accurate motion capture.

The present invention relates to methods for remotely and intelligently tuning movement disorder of therapy systems. The present invention still further provides methods of quantifying movement disorders for the treatment of patients who exhibit symptoms of such movement disorders including, but not limited to, Parkinson's disease and Parkinsonism, Dystonia, Chorea, and Huntington's disease, Ataxia, Tremor and Essential Tremor, Tourette syndrome, stroke, and the like. The present invention yet further relates to methods of remotely and intelligently or automatically tuning a therapy device using objective quantified movement disorder symptom data to determine the therapy setting or parameters to be transmitted and provided to the subject via his or her therapy device. The present invention also provides treatment and tuning intelligently, automatically and remotely, allowing for home monitoring of subjects.

The present disclosure relates to a neuromodulation and/or neurostimulation system comprising at least the following components: at least one sensing unit, at least control unit, at least one stimulation unit, at least one Central Nervous System (CNS) stimulation module, at least one Peripheral Nervous System (PNS) stimulation module,wherein at least one of the components of the neuromodulation and/or neurostimulation system is implantable.

An apparatus for treating neurological disorders comprising at least one electrode implantable in a patient's brain and a processing and stimulation device connected to the at least one electrode. The processing and stimulation device comprises at least one stimulation module adapted to generate a stimulation signal characterised by a plurality of parameters; at least one acquisition module adapted to acquire a signal characteristic of cerebral activity and determine its power in at least one frequency band; and at least one control module of at least one parameter of the stimulation signal as a function of the power of the signal characteristic of cerebral activity acquired, based on a transfer function having a saturating trend, wherein the transfer function is configured to set the at least one parameter of the stimulation signal differently dependent on a plurality of power ranges, by keeping the parameter within a predetermined stimulation range.

The present disclosure provides methods, devices and systems for assessing/evaluating the verbal fluency of a user by obtaining a speech (audial/acoustic signal) from a user, detecting disrupted/stuttered and fluent speech time-intervals in the speech, calculating a Disrupted-time value and Fluent-time value based on the disrupted/stuttered and fluent speech time-intervals respectively, and deriving a speech efficiency score for the user/speech based on the Disrupted-time value and Fluent-time value.