An evaluation device includes a display unit; a gaze point detection unit detecting a position of a gaze point of a subject; a display control unit causing the display unit to display a video for task of causing the subject to gaze at a final arrival point of a moving object; a region setting unit setting a movement route region corresponding to a movement route of the moving object according to a movement rule and a final arrival point region corresponding to the final arrival point; a determination unit determining, based on the position of the gaze point, whether the gaze point exists in the movement route region and the final arrival point region in a display period; a calculation unit calculating gaze point data in the display period based on a determination result; and an evaluation unit obtaining evaluation data of the subject based on the gaze point data.

Systems and methods for detecting a cognitive diseases and/or impairments in humans are disclosed. The method may include providing a saliva sample from a human subject, and subjecting at least a portion of the saliva sample to a spectroscopic analysis to produce a sample spectroscopic signature. The method may also include analyzing the produced sample spectroscopic signature using a predetermined statistical model. The predetermined statistical model may be based on spectroscopic signatures for a plurality modeling samples, and the spectroscopic signatures for each of the plurality of modeling samples may be associated with one of a plurality of predetermined cognitive categories. Additionally, the method may include correlating the produced sample spectroscopic signature with one of the plurality of predetermined cognitive categories based on the spectroscopic signatures for each of the plurality of modeling samples of the predetermined statistical model.

A computer-implemented method and system includes accessing neurophysiological and neurovascular data recorded during sleep. A function mapping is executed from said neurophysiological and neurovascular data to a target that is one of a glymphatic flow marker, a molecular analysis marker of neurodegeneration, or a neuroimaging marker of neurodegeneration. A target prediction model is output based on the function mapping. The target prediction model can receive new neurophysiological and neurovascular data and output a predicted marker of neurodegeneration.

Systems and methods of the present disclosure are directed to systems and methods for treating cognitive dysfunction in a subject in need thereof. The system can include eyeglasses, a photodiode positioned to detect ambient light, light sources, and an input device. The system can include a neural stimulation system that retrieves a profile and selects a light pattern having a fixed parameter and a variable parameter. The neural stimulation system can set a value of the variable parameter of the light pattern, construct an output signal, and then provide the output signal to the light sources to direct light towards the fovea.

A sensor (30) for measuring a biological potential of an individual, comprising: a measurement electrode (31) comprising a base (32), at least one leg intended to come into contact with an anatomical zone of the individual and at least one electrical connection member (38), at least one locking member (45) configured to cooperate in a reversible manner with at least one complementary locking member (25) on an external support (10) so as to removably fasten the sensor (30) to the external support (10), the locking member (45) being separate from the electrical connection member (38), a protection element (40) made from a resilient material and delimiting a recess (41) in which the leg extends.

A system is provided for tracking, in a distributed water infrastructure, water usage by category. The system may comprise at least one processor configured to receive from at least one sensor associated with the distributed water infrastructure signals indicative of water usage in the distributed water infrastructure. The system may, based on the signals indicative of water usage, construct a plurality of profiles. The system may assign each profile to one of a plurality of water usage categories. The system may collect, from the at least one sensor, signals indicative of water usage for substantially all water delivered through the distributed water infrastructure in a time period. The system may construct a plurality of water usage profiles in the aggregate, encompassing substantially all water delivered through the distributed water infrastructure in the time period. The system may assign each constructed water usage profile to one of the plurality of water usage categories. The system may output, for display, water usage for the time period for each of the plurality of water usage categories.

A cognitive function evaluation device includes: an obtainment unit configured to obtain, as gait data, at least one of first data and second data, the first data indicating a sway amount of a body of a subject during walking in a first walking section from start of walking of the subject to a predetermined number of steps, and the second data indicating a sway amount of the body of the subject during walking in a second walking section in a double task state in which the subject is walking while doing a given assignment, the second walking section being after the first walking section; a calculation unit configured to calculate a feature value based on the gait data; an evaluation unit configured to evaluate a cognitive function of the subject, based on the feature value; and an output unit configured to output a result of evaluation by the evaluation unit.

A cognitive function evaluation method in a cognitive function evaluation device that evaluates a cognitive function based on a walking motion of a subject includes: acquiring walking data related to walking of the subject; detecting, from the walking data, at least one of an angle of an ankle joint of one foot and an angle of a knee joint of one leg of the subject; and determining a cognitive function level of the subject using at least one of the angle of the ankle joint and the angle of the knee joint.

An apparatus and method for employing the macro- and micro-structure of sleep and similar states of consciousness to optimize pain-treatment are disclosed wherein an objective biomarker of pain-related sleep disturbance guides pain treatment from a sleep perspective. Furthermore, this concept can be extended to states of reduced consciousness such as coma or sedation. Additionally, it could be applied on individuals who are non-communicative due to injury, disease, language issues and/or infancy.

The present invention is directed to devices and methods for rhythmic therapy. A system streams a patient specific audio file to a patient for therapy or rehabilitation while the patient is performing an exercise, where the audio comprises a musical track selected from a library of musical tracks, and simultaneously playing a second audio file with a motivational message, for example, and further where the tempo of the track, or the selection of the tracks are changed based on data received from sensors and determining if the patient is improving or regressing.