A computing device for enhancing communications is disclosed. The computing device includes a memory configured to store data, a video camera configured to receive video input data, and a microphone configured to receive audio input data. The computing device also includes a processor that is configured to analyze the received video input data, the received audio input data, and the data stored in the memory. The computing device further includes a visual display device that is configured to output a visual display based on the processor analysis, and a speaker output device that is configured to output an audio signal based on the processor analysis.

A system for assessing the physiological state of a subject, comprising: a task delivery module configured to communicate to a subject at least two sets of information, each set of information relating to a cognitive task requiring a spoken response from the subject; a response detection module configured to record the respective spoken responses from the subject as an audio signal, the response detection module comprising a microphone; an analysis module configured to analyze the audio signals corresponding to the respective spoken responses recorded by the response detection module to determine from the respective spoken responses one or more characteristics indicative of the physiological state of the subject, compare said characteristics from the respective spoken responses, and determine the physiological state of the subject based on said comparison.

Systems and methods for generating a numerical model of the human head are provided. A numerical model may be created by generating a data array in a magnetic resonance modeling system, each cell of the array corresponding to a location in the head. The cells may be grouped into one or more regions, each group corresponding to a segment of the head. The cells of the array may be populated with values corresponding to tissue properties relevant to MR imaging. Tissue property values may be selected for each region based on one or more probability distributions. For each region and each tissue property, a value may be selected based on a corresponding probability distribution. Selected tissue property values may be input into cells in the array corresponding to the region with which the probability distribution is associated. The numerical model may be used as an input to an MRI simulator.

A system is provided for detecting abnormal consumption in one portion of a distributed water infrastructure while normal water usage occurs in another portion of the distributed water infrastructure. The system may comprise at least one processor. The system may receive from at least one sensor associated with the distributed water infrastructure indications of regular water usage. The system may determine, from a plurality of indications received over a time period, a plurality of baseline water usage profiles. The system may receive from the at least one sensor a current water usage profile. The system may compare the current water usage profile with the plurality of baseline water usage profiles. The system may determine an abnormal water consumption based on the comparison between the current water usage profile and the plurality of baseline water usage profiles. The system may generate an abnormal water consumption signal when abnormal water consumption is determined.

A system is provided for differentiating between overlapping water events in a distributed water infrastructure including a plurality of water appliances. The system may comprise at least one processor. The system may repeatedly measure at least one overall water usage indicator of the distributed water infrastructure, the at least one water usage indicator including at least one of an overall flow rate and an overall flow volume in the distributed water infrastructure. The system may detect, in the repeated measurements, a first sustained increase. The system may store in memory a first indicator of the first sustained increase. The system may attribute in memory the first sustained increase to a first water event in the distributed water infrastructure. The system may, during the first sustained increase, detect in the overall measurements a second sustained increase. The system may store in memory a second indicator of the second sustained increase. The system may attribute, in memory, the second sustained increase to a second water event in the distributed water infrastructure. The system may detect, following initiation of the first sustained increase and the second sustained increase, in the repeated measurements a decrease in the overall water usage indicator. The system may attribute to the decrease a third indicator. The system may compare the third indicator with at least one of the first indicator and the second indicator stored in memory to determine a substantial match and determine a cessation of at least one of the first water event and the second water event. The system may initiate an action based on the cessation determination.

A neuromodulation system for treatment of physiological disorders. The system includes one or more stimulators for stimulating one or more cranial nerves; one or more detectors configured for detecting a predetermined physiological state; and a control unit that controls nerve stimulation by the one or more stimulators so that it is synchronized with the at least one predetermined physiological state detected by the one or more detectors. A method of neuromodulating a patient for treatment of physiological disorder. The method includes the steps of detecting a predetermined physiological state and applying stimulation to one of the cranial nerves during the predetermined physiological state by one or more stimulators of a neuromodulation system.

Embodiments of the present disclosure provide a system and method for using facial recognition and mimicry workflows to train cognitive and emotional empathy. The system and methods comprise the use of physiological measurements (e.g., EEG, etc.) in combinations with facial recognition to detect user affect and modify one or more cognitive screening instruments to further promote a user affect. One or more specific emotions associated with one or more specific negative cognitive bias are targeted to influence affect. One or more specific psychopathology may be treated using an emotional recognition training component within a computerized cognitive-bias modification regimen. The regimen may comprise the identification, targeting, and modification of emotions and may utilize one or more facial inputs, cognitive tasks, facial recognition and facial mimicry protocols to adaptively modify one or more attributes of one or more computerized stimuli or interactions within a computerized platform or platform-product.

The digital personalized medicine system uses digital data to assess or diagnose symptoms of a subject to provide personalized or more appropriate therapeutic interventions and improved diagnoses. The use of prioritized questions and answers with associated feature importance can be used to assess mental function and allow a subject to be diagnosed with fewer questions, such that diagnosis can be repeated more often and allow the dosage to be adjusted more frequently. Pharmacokinetics of the subject can be estimated based on demographic data and biomarkers or measured, in order to determine a treatment plan for the subject. Also, biomarkers can be used to determine when the patient may be at risk for experiencing undesirable side effects and the treatment plan adjusted accordingly.

A plurality of individually addressable electrodes is supported by a housing. The individually addressable electrodes are for at least one of applying stimulation electrical signals to skin of a user and detecting biometric electrical signals from the skin of the user. At least one of a signal detector is provided for detecting the biometric electrical signals and a signal generator is provided for generating the stimulation electrical signals. An electrode multiplex circuit is provided for addressing the plurality of individually addressable electrodes by at least one of routing the biometric electrical signals from the skin of the user through more than one of the plurality of individually addressable electrodes to the signal detector and routing the stimulation electrical signals from the signal generator through more than one of the plurality of individually addressable electrode to the skin of the user. A microprocessor is provided for controlling at least one of the signal detector, the signal generator, the electrode multiplex circuit.

Techniques for generating and administering an oculo-cognitive addition test. Some aspects include identifying, by a system, a set of numbers that are to be displayed to a user during a trial of a cognitive test. The set of numbers includes at least two numbers. The system can administer the trial of the cognitive test, including, for each number in the set of numbers: displaying the number at a particular position of a display environment; tracking, by the system and using one or more optical sensors, eye movement of the user seeking the number in the display environment; and receiving, by the system and after having displayed the number for a time, a command that is to advance or end the cognitive test.