A method (10) that encodes electrode locations to a mean scalp mesh for adaptation to subsequent image scans.

Systems configured to acquire temperature signals from an Abreu Brain Thermal Tunnel (ABTT), to analyze the temperatures signals, and to determine a condition of a human body from the analysis, and a method for doing the same, are described. In addition, systems for application of thermal signals to the ABTT for treatment of conditions are described.

A neurostimulation system senses electrographic signals from the brain of a patient, extracts features from the electrographic signals, and when the extracted features satisfy certain criteria, detects a neurological event type. A mapping function relates the detected neurological event type to a stimulation parameter subspace and a default stimulation parameter set where the values of the stimulation parameters define an instance of stimulation therapy for the patient. The decision whether to implement a stimulation parameter subspace or a default stimulation parameter set may be informed by integrating other information about a state of the patient. A stimulation parameter subspace or stimulation parameter set may optimized by testing it against various thresholds until certain effectiveness criteria is satisfied. The neurological event type may be one of several electrographic seizure onset types.

Success in generating or curtailing seizures is related to their onset time, with inhibition proving less effective on earlier-onset afterdischarges. To identify targets for intervention, fMRI or simultaneous fMRI-LFP is used to map the seizure network of afterdischarges initiated from the dorsal and ventral hippocampus.

Disclosed are devices, electrodes, systems, methods, and other implementations, including a subdural sound that includes an elongated body configured to be placed within a subdural space of a brain area of a patient, with the elongated body defining a receiving channel to receive a displaceable electrode to be tangentially placed at a target site in the subdural space. The subdural sound further includes a curved tip at a distal end of the elongated body, the curved tip configured for angled insertion into the subdural space of the patient to advance the elongated body to the target site in the subdural space.

A method and a system for processing an electroencephalogram (EEG) signal are provided. The method for processing the EEG signal includes: performing a spike detection on the EEG signal to obtain a spike distribution waveform, performing an instantaneous frequency oscillation energy analysis on the EEG signal to obtain multiple energy distribution waveforms; performing a complexity analysis on the EEG signal to obtain a complexity change waveform, obtaining a determination result of a specified neural waveform based on the spike distribution waveform, the energy distribution waveforms, and the complexity change waveform, and outputting the determination result.

An illustrative system includes a stimulation device configured to apply stimulation to a recipient, a sensing device configured to detect a physiological condition of the recipient, and a processing unit communicatively coupled to the stimulation device and the sensing device. The processing unit determines a stimulation strategy that is customized to the recipient and includes stimulation frames and stimulation gaps. The processing unit then directs the stimulation device to apply the stimulation to the recipient in accordance with the stimulation strategy by applying the stimulation only during time that corresponds to the stimulation frames. The processing unit also directs the sensing device to detect the physiological condition of the recipient in accordance with the stimulation strategy by detecting only during time that corresponds to the stimulation gaps. Based on the detected physiological condition, the processing unit performs an action. Corresponding systems, methods, and apparatuses are also disclosed.

A method comprising detecting an epileptic event in a patient; applying an electrical therapy to a first target area in at least one of a brain region or a cranial nerve of said patient in response to said detecting; receiving a body signal responsive to the electrical therapy, wherein said body signal is selected from an autonomic signal, a neurologic signal, a metabolic signal, an endocrine signal, or a tissue stress marker signal; determining whether said body signal indicates that said electrical therapy has an efficacious effect; and terminating the application of said electrical therapy if the response indicates that the electrical therapy has an efficacious effect. An apparatus capable of performing the method. A non-transitive, computer-readable storage device for storing data that when executed by a processor, perform the method.

Embodiments may provide multimodal diagnostic systems and methods for detecting neurological disorders, such as Alzheimer's disease (AD), Parkinson's disease (PD), depression, PTSD, schizophrenia, dementia and many others. For example, a system for monitoring brain activity may comprise a plurality of sensors, each adapted to monitor a physical or physiological parameter and output a signal representing the monitored physical or physiological parameter, wherein the plurality of sensors includes at least one sensor configured to monitor a brain activity parameter, a data collection device adapted to receive the plurality of signals from the plurality of sensors and to process the signals to form digital data representing the monitored physical or physiological parameters, and a data processing device adapted to process digital data representing the monitored physical or physiological parameters to determine presence of a neurological disorder or condition.

An approach for providing assistance to an operator of a vehicle during a medical event and/or driving impairment is disclosed. The approach includes determines driving profile of a driver, monitors the driver during a trip, identifies an occurrence of the medical event associated with the driver. The approach generates an initial action list in responsive the occurrence of the medical event. The approach executes the initial action list and determines whether the driver is cognizant. The approach generates a subsequent action list in responsive to the driver is not cognizant and executes the subsequent action list.