Closed cavity adjustable sensor mount systems and methods are disclosed. The sensor mount systems include a sealed, closed cavity enclosing a sensor and forming a closed cavity sensor assembly. The closed cavity sensor assembly may be tilted and/or translated relative to a platform in order to adjust the orientation of the sensor to align it with an imaging optical axis. Following alignment, the closed cavity sensor assembly may be permanently or reversibly fixed in place. The closed cavity adjustable sensor mount systems may be part of medical imaging systems such as endoscopic imaging systems and/or open field imaging systems.

A monitoring apparatus includes a wearable electronic device having an audio port and a headset having at least one earbud, at least one physiological and/or environmental sensor, and circuitry that processes signals produced by the at least one physiological and/or environmental sensor and transmits the processed signals to the electronic device via the audio port. The headset may include a microphone in audio communication with the electronic device via the audio port, and the circuitry modulates audio signals produced by the microphone and signals produced by the at least one physiological and/or environmental sensor for transmission to the electronic device via the audio port. The circuitry may power the at least one physiological and/or environmental sensor via power supplied by the electronic device through the audio port and may include a processor that coordinates collection, modulation, and/or transmission of signals produced by the at least one physiological and/or environmental sensor.

A method for detecting cancerous status of a suspected lymph node (LN) to be cancerous. The method includes measuring fatty acid oxidation (FAO) in the suspected LN by measuring a charge transfer resistance (R.sub.CT) associated with the suspected LN, and detecting, utilizing one or more processors, a cancerous status of the suspected LN. Detecting the cancerous status of the suspected LN includes detecting the suspected LN is cancer involved if the measured R.sub.CT is less than a reference R.sub.CT value, or detecting the suspected LN is healthy if the measured R.sub.CT is more than the reference R.sub.CT value.

In a method and magnetic resonance apparatus for acquiring a high-resolution magnetic resonance image dataset of at least one limited body region having at least one anatomical structure of a patient, an overview image dataset is first acquired, using which an item of position information of the at least one anatomical structure is ascertained, the item of position information designating an exact position of the at least one anatomical structure and/or a relative position of the at least one anatomical structure relative to the reference body region. A high-resolution magnetic resonance image dataset of the anatomical structure is then created using the position information and the high-resolution magnetic resonance image dataset is evaluated. The evaluated high-resolution image data is then made available in electronic form.

A piece of medical information, e.g., a medical image of tissue, may be received for processing and analysis on a computing device or system. A region of the medical image may be analyzed to determine a presence of one or more contours in the region. One or more properties of the one or more contours may be extracted, where the one or more properties are inputted into a first algorithm to determine an indication of cancer for the region. The indication of cancer may be inputted into a second algorithm to generate a cancer score for the region.

A lesion tracking system (10) includes a data interface (12), a computation engine (18), and a visualization engine (26). The data interface (12) is configured to receive an identification (44) and measurements (56) of at least one target lesion (42), which includes at least one undetermined target lesion (52) according to a plurality of determined categories (54), and each undetermined target lesion (52) is quantified differently according to each of the plurality of determined categories (54). The computation engine (18) is configured to compute a range of quantified measurements according to each determined category for each undetermined target lesion (52), and to compute a quantified total range (70) for the at least one target lesion based on a quantified measurement (62) for each determined target lesion and the computed range for each of the at least one undetermined target lesion. The visualization engine (26) is configured to generate a human readable display of the computed quantified total range (70) for the at least one target lesion.

Apparatus and systems are described that include physical media related to accepting at least one attribute associated with an individual from a licensed health care provider and/or presenting an output of an artificial sensory experience associated with a request to measure at least one effect of a bioactive agent on the attribute associated with individual.

The present disclosure relates to compounds that are useful as near-infrared fluorescence probes, wherein the compounds include i) a pteroyl ligand that binds to a target receptor protein, ii) a dye molecule, and iii) a linker molecule that comprises an amino acid or derivative thereof. The disclosure further describes methods and compositions for incorporating the compounds as used for the targeted imaging of non-small cell lung cancer (NSCLC) in human subjects. Conjugation of the amino acid linking groups increase specificity and detection of the compound. Methods and compositions for use thereof in diagnostic imaging are contemplated.

Aspects of the invention include methods for visualizing lymphatic tissue in an ocular region, e.g., the cornea, of a living subject, such as a mouse or human. In certain embodiments, the methods include contacting the region with a fluorescently-labeled lymphatic tissue-specific dye, e.g., FITC or rhodamine labeled dextran, and detecting the labeled dye to visualize lymphatic tissue in the region, where the visualization may vary, from an image obtained at a single time to a video over a period of time. The invention finds use in a variety of different applications, including research and therapeutic applications.

BioMEMS/NEMS appliance biologically monitors an individual, using biosensors to detect cellular components. Data is simulated or analyzed using systems-biology software, which provides diagnostic or therapeutic guidance.